X连锁精神发育迟滞相关基因JARID1C研究进展

doi:10.3724/SP.J.1005.2010.00205

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HEREDITAS ›› 2010, Vol. 32 ›› Issue (3): 205-210.doi: 10.3724/SP.J.1005.2010.00205

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Progress on X-linked mental retardation related gene JARID1C

LEI Xu, GAO Xiao-Cai, ZHANG Fu-Chang

Institute of Population and Health, College of Life Science, Northwest University, Xi’an 710069, China

Received:2009-06-27 Revised:2009-10-30 Online:2010-03-20 Published:2010-03-15
Contact: GAO Xiao-Cai;fuchang zhang E-mail:gaoxc@nwu.edu.cn;zhfch@nwu.edu.cn

Abstract

Abstract:

JARID1C is one of the genes related to X-linked mental retardation. Its express product influences transcription and expression of the related genes in brain nervous system, and may be associated with human cognitive ability. Study on the functions of JARID1C not only helps to understand its molecular role in mental retardation and human cognitive ability, but also provides references for clinical diagnosis and prevention of mental retardation. This article reviews the progresses on JARID1C in location, isolation, physiological functions, and cognitive functions of its encoding product. The future re-search work of JARID1C is also discussed.

Key words: JARID1C gene, mental retardation, cognitive ability, gene mutation

LEI Xu, GAO Xiao-Cai, ZHANG Fu-Chang. Progress on X-linked mental retardation related gene JARID1C[J]. HEREDITAS, 2010, 32(3): 205-210.

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Progress on X-linked mental retardation related gene JARID1C

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