动物隐花色素研究进展

doi:10.3724/SP.J.1005.2014.0864

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HEREDITAS(Beijing) ›› 2014, Vol. 36 ›› Issue (9): 864-870.doi: 10.3724/SP.J.1005.2014.0864

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Research progresses in animal cryptochromes

Yuancheng Lu, Xiaohui Wu

State Key Laboratory of Genetic Engineering and National Center for International Research of Development and Disease, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai 200433, China

Received:2014-05-23 Online:2014-09-20 Published:2014-09-20

Abstract

Abstract: Animal cryptochromes are widely known to regulate circadian clock and can be divided into two types. Type I cryptochromes receive light to initiate the degradation of transcriptional inhibitors, whereas type II cryptochromes directly act as light-irresponsive transcriptional inhibitors. Recent studies reveal that animal cryptochromes also have functions in immune response and carbohydrate metabolism, and are required in light-induced chemical magnetoreception in animals like Drosophila. The further researches on animal cryptochromes will improve our understanding of magnetoreception and aid development of therapeutic treatment of diseases such as diabetes. In this review, we summarize the research progresses of animal cryptochromes, with an emphasis on its cloning, expression, and structural and functional studies.

Key words: animal, cryptochrome, circadian clock, chemical magnetoreception

Yuancheng Lu, Xiaohui Wu. Research progresses in animal cryptochromes[J]. HEREDITAS(Beijing), 2014, 36(9): 864-870.

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Research progresses in animal cryptochromes

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