基于转录组学分析秀丽线虫对乙酸钙不动杆菌的摄食偏好行为

doi:10.16288/j.yczz.24-364

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Hereditas(Beijing) ›› 2025, Vol. 47 ›› Issue (7): 786-796.doi: 10.16288/j.yczz.24-364

• Research Article • Previous Articles Next Articles

Analysis of food preference behavior of C. elegans to Acinetobacter calcoaceticus based on transcriptomics

Jiaojiao Liu¹^,²(), Xinhe Lu¹^,²(), Hongyan Yin³, Hailong Zhou²(), Hanzeng Li¹(), Shunqing Xu¹()

1. School of Environmental Science and Engineering, Hainan University, Haikou 570228, China
2. School of Life Health, Hainan University, Haikou 570228, China
3. School of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China

Received:2024-12-02 Revised:2025-01-15 Online:2025-07-20 Published:2025-03-13
Contact: Hailong Zhou, Hanzeng Li, Shunqing Xu E-mail:jjiaoliu@hainanu.edu.cn;22210710000043@hainanu.edu.cn;hlongzhou@163.com;hanzeng.li@hainanu.edu.cn;Xus@hainanu.edu.cn
Supported by:
Hainan Province Key Research and Development Project(ZDYF2022SHFZ321);Natural Science Foundation of Hainan Province(823QN230)

Abstract

Abstract:

C. elegans is one of the most important model organisms in biological research, exhibiting distinct preferences for bacterial food sources in natural environments. Acinetobacter calcoaceticus(Ac) is a widely distributed Gram-negative bacterium commonly found in moist habitats. This study investigates the feeding preferences, pharyngeal pumping rates, body fat content, lifespan, and gene expression differences of C. elegans when fed different bacterial food sources. The results reveal that feeding on Ac induces lipid metabolism changes, leading to altered feeding preferences. Transcriptomic analysis was performed to compare the gene expression profiles of C. elegans fed on Escherichia coli OP50 and Ac, offers a novel perspective on the mechanisms underlying C. elegans microbe interactions.

Key words: C. elegans, Acinetobacter calcoaceticus, food preferences, transcriptome

Jiaojiao Liu, Xinhe Lu, Hongyan Yin, Hailong Zhou, Hanzeng Li, Shunqing Xu. Analysis of food preference behavior of C. elegans to Acinetobacter calcoaceticus based on transcriptomics[J]. Hereditas(Beijing), 2025, 47(7): 786-796.

Figures/Tables 5

References 29

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Analysis of food preference behavior of C. elegans to Acinetobacter calcoaceticus based on transcriptomics

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