二脂酰甘油酰基转移酶2 (Acyl CoA: Diacylgycerol Acyltransferase 2, DGAT2)是生物体内的一种非常重要的酶, 其主要机制是使二酰甘油加上脂肪酸酰基辅酶A以共价健结合形成三酰甘油。编码该酶的基因有DGAT2和DGAT1。文章综述了DGAT2基因的发现、定位、结构、生物学效应及其遗传多态性与生产性能的关系, 并对其应用前景进行了展望。

Diacylgycerol acyltransferase2 (DGAT2) is an important enzyme in many organisms. DGAT2 catalyzes the final step of triacylglycerol (TAG) biosynthesis by converting diacylgycerol (DAG) and fatty acyl-coenzyme A (CoA) into TAG. This enzyme is encoded by both DGAT2 and DGAT1 genes. This paper reviews the discovery of the DGAT2 gene, its structure, chromosomal location and biological effect. The relationship between its genetic polymorphisms and animal performance traits is also discussed. The review ends with future prospects.