人体游离循环DNA的研究进展

胡影，倪虹

doi:10.3724/SP.J.1005.2008.00815

遗传 >

2008 , Vol. 30 >Issue 7: 815 - 820

DOI: https://doi.org/10.3724/SP.J.1005.2008.00815

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人体游离循环DNA的研究进展

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1. 南开大学生命科学学院, 天津 300071;
2. 南开大学医学院, 天津 300071

收稿日期: 2007-11-29

修回日期: 2008-03-17

网络出版日期: 2008-07-10

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Advance in human free circulating DNA

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1. College of Life Science, Nankai University, Tianjin 300071, China;
2. Medical College, Nankai University, Tianjin 300071, China

Received date: 2007-11-29

Revised date: 2008-03-17

Online published: 2008-07-10

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摘要

游离循环DNA是一种细胞外游离状态的DNA, 在动植物及人的体液中都检测到了它的存在。对游离循环DNA的检测已经应用在疾病的监控、胎儿的产前诊断及肿瘤的研究中。文章介绍了循环DNA的生物学特征, 并对近年来游离循环DNA的研究和应用进展做了简单的回顾。

关键词： 肿瘤; 产前诊断; 疾病诊断; 游离循环DNA

本文引用格式

胡影，倪虹 . 人体游离循环DNA的研究进展[J]. 遗传, 2008 , 30(7) : 815 -820 . DOI: 10.3724/SP.J.1005.2008.00815

Abstract

Free circulating DNA is one kind of extracellular free DNA, which was examined in the zoology, botany and the human’s body fluid. The detection of free circulating DNA had already been applied in monitoring the disease, embryo’s pre-natal diagnosis, tumor research. This article reviewed some biology characteristics of free circulating DNA, the recent researches of free circulating DNA and its application.

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