X连锁精神发育迟滞相关基因JARID1C研究进展
收稿日期: 2009-06-27
修回日期: 2009-10-30
网络出版日期: 2010-03-15
基金资助
陕西省科技研究发展计划项目(编号：2007K01-25)资助
Progress on X-linked mental retardation related gene JARID1C
Received date: 2009-06-27
Revised date: 2009-10-30
Online published: 2010-03-15
雷徐，高晓彩，张富昌 . X连锁精神发育迟滞相关基因JARID1C研究进展[J]. 遗传, 2010 , 32(3) : 205 -210 . DOI: 10.3724/SP.J.1005.2010.00205
JARID1C is one of the genes related to X-linked mental retardation. Its express product influences transcription and expression of the related genes in brain nervous system, and may be associated with human cognitive ability. Study on the functions of JARID1C not only helps to understand its molecular role in mental retardation and human cognitive ability, but also provides references for clinical diagnosis and prevention of mental retardation. This article reviews the progresses on JARID1C in location, isolation, physiological functions, and cognitive functions of its encoding product. The future re-search work of JARID1C is also discussed.
Key words： JARID1C gene; mental retardation; cognitive ability; gene mutation
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