多肽配体技术在植物功能基因组学中的应用前景
收稿日期: 2009-10-29
修回日期: 2009-12-31
网络出版日期: 2010-05-24
基金资助
国家转基因生物新品种培育科技重大专项(编号：2009ZX08009-011B)资助
Peptide aptamer: a powerful potential tool in plant functional genomics
Received date: 2009-10-29
Revised date: 2009-12-31
Online published: 2010-05-24
公丕昌，王丽，贺超英 . 多肽配体技术在植物功能基因组学中的应用前景[J]. 遗传, 2010 , 32(6) : 548 -554 . DOI: 10.3724/SP.J.1005.2010.00548
Aptamer is a newly invented tool for gene interference in vivo with highly specificity. An aptamer is designed to specifically target a protein and inhibit its biochemical roles for ascertaining its biological functions. Here, we briefly review the major progress of peptide aptamer in validating gene function, and emphasize its promising application in both plant functional genomics and peptide-mediated broad-spectrum plant resistance to diverse phytoviruses. The strategies to overcome the potential risks are covered as well.
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