转录因子CCAAT增强子结合蛋白&beta;(C/EBP &beta;)的研究进展

高运臻，潘玉春

doi:10.3724/SP.J.1005.2011.00198

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2011 , Vol. 33 >Issue 3: 198 - 206

DOI: https://doi.org/10.3724/SP.J.1005.2011.00198

综述

转录因子CCAAT增强子结合蛋白β(C/EBP β)的研究进展

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1. 上海交通大学农业与生物学院, 上海 200240 2. 上海市兽医生物技术重点实验室, 上海 200240

收稿日期: 2010-05-21

修回日期: 2010-09-04

网络出版日期: 2011-02-25

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Progress of transcription factor CCAAT enhancer binding protein β

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1. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China 2. The Key Laboratory of Veterinary Biotechnology, Shanghai 200240, China

Received date: 2010-05-21

Revised date: 2010-09-04

Online published: 2011-02-25

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摘要

CCAAT增强子结合蛋白β(CCAAT enhancer binding protein, C/EBP β)是CCAAT增强子结合蛋白家族的一员。该家族是碱性亮氨酸拉链大家族的一个亚家族, 在细胞分化、能量代谢、生长发育等多个进程中发挥作用。文章就C/EBP β的结构、表达调控和生物学功能做一综述, 并对研究应用进行了展望。

关键词： CCAAT增强子结合蛋白; 结构; 表达调控; 生物学功能

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高运臻，潘玉春 . 转录因子CCAAT增强子结合蛋白β(C/EBP β)的研究进展[J]. 遗传, 2011 , 33(3) : 198 -206 . DOI: 10.3724/SP.J.1005.2011.00198

Abstract

CCAAT enhancer binding protein β (C/EBP β) belongs to CCAAT enhancer binding protein (C/EBP) family, which is a subfamily of basic leucine zipper (bZIP) protein family. C/EBP family plays important roles in many processes such as cell differentiation, metabolism, and development. In this paper, the structure, expression regulation, and function of C/EBP β were reviewed.

Key words： CCAAT enhancer protein; structure; regulation of expression; function

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