[1] Wyatt GR, Cohen SS. A new pyrimidine base from bacteriophage nucleic acids. Nature, 1952, 170(4338): 1072-1073.
[2] Penn NW, Suwalski R, O'Riley C, Bojanowski K, Yura R. The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochem J, 1972, 126(4): 781-790.
[3] Kothari RM, Shankar V. 5-Methylcytosine content in the vertebrate deoxyribonucleic acids: species specificity. J Mol Evol, 1976, 7(4): 325-329.
[4] Tahiliani M, Koh KP, Shen YH, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science, 2009, 324(5929): 930-935.
[5] Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 2009, 324(5929): 929-930.
[6] Liutkevi?iūt? Z, Lukinavi?ius G, Masevi?ius V, Daujotyt? D, Klimašauskas S. Cytosine-5-methyltransferases add aldehydes to DNA. Nat Chem Biol, 2009, 5(6): 400-402.
[7] Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron, 2007, 53(6): 857-869.
[8] Popp C, Dean W, Feng SH, Cokus SJ, Andrews S, Pellegrini M, Jacobsen SE, Reik W. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature, 2010, 463(7284): 1101-1105.
[9] Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science, 2001, 293(5532): 1089-1093.
[10] Zhu JK. Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet, 2009, 43: 143-166.
[11] Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature, 2010, 466(7310): 1129-1133.
[12] Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature, 2010, 468(7325): 839-843.
[13] Mohr F, Döhner K, Buske C, Rawat VPS. TET genes: new players in DNA demethylation and important determinants for stemness. Exp Hematol, 2011, 39(3): 272-281.
[14] Cokol M, Nair R, Rost B. Finding nuclear localization signals. EMBO Rep, 2000, 1(5): 411-415.
[15] Zhang HK, Zhang X, Clark E, Mulcahey M, Huang S, Shi YG. TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine. Cell Res, 2010, 20(12): 1390-1393.
[16] Globisch D, Münzel M, Müller M, Michalakis S, Wagner M, Koch S, Brückl T, Biel M, Carell T. Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One, 2010, 5(12): e15367.
[17] Szwagierczak A, Bultmann S, Schmidt CS, Spada F, Leonhardt H. Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res, 2010, 38(19): e181.
[18] Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell, 2011, 8(2): 200-213.
[19] Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing JR. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia, 2003, 17(3): 637-641.
[20] Holmfeldt L, Mullighan CG. The role of TET2 in hematologic neoplasms. Cancer Cell, 2011, 20(1): 1-2.
[21] Li WW, Liu M. Distribution of 5-hydroxymethylcytosine in different human tissues. J Nucleic Acids, 2011, 2011: 870726.
