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拟南芥SUMO底物的研究进展

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  • 中国农业科学院作物科学研究所, 农业部北京大豆生物学重点实验室, 农作物基因资源与遗传改良国家重大科学工程, 北京100081

收稿日期: 2012-10-15

  修回日期: 2013-02-20

  网络出版日期: 2013-06-25

基金资助

国家自然科学基金项目(编号:30670189)资助

Advances on SUMO substrates in Arabidopsis

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  • Ministry of Agriculture Key Lab of Soybean Biology (Beijing), National Key Facility of Crop Gene Resource and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China

Received date: 2012-10-15

  Revised date: 2013-02-20

  Online published: 2013-06-25

摘要

SUMO(Small ubiquitin-related modifier)化修饰是普遍存在于真核生物中的一种翻译后修饰, 在很多细胞过程中发挥重要作用。文章阐述了拟南芥中SUMO底物的最新研究进展。首先介绍SUMO化修饰过程, SUMO底物的鉴定, 包括鉴定方法的进展和鉴定成果。然后依据底物的亚细胞定位、生理功能和参与的生理生化过程对其进行分类和分析, 以期更好地理解蛋白质SUMO化修饰方式在植物生长发育中的功能。

本文引用格式

郭敏霞 傅永福 . 拟南芥SUMO底物的研究进展[J]. 遗传, 2013 , 35(6) : 727 -734 . DOI: 10.3724/SP.J.1005.2013.00727

Abstract

SUMO (Small ubiquitin-related modifier) modification, one of the essential posttranslational modifications in eukaryotes, plays an important role in various cellular processes. This review summarized the recent progresses on SUMO substrates in Arabidopsis. We firstly described the pathway of SUMO conjugation, and then focused on screening for SUMO substrates, including the methods of identification and SUMO substrates identified. Finally, we classified these substrates on the basis of their subcellular localization, functions, and biological processes. It is expected to provide the basis for better un-derstanding the roles of sumoylation of proteins in plants.

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