李美婷, 曹林林, 杨洋 . 表观遗传修饰在糖脂代谢中的作用[J]. 遗传, 2014 , 36(3) : 200 -207 . DOI: 10.3724/SP.J.1005.2014.0200

[1] Gopalakrishnan S, Van Emburgh BO, Robertson KD. DNA methylation in development and human disease. Mutat Res, 2008, 647(1-2): 30-38. <\p>

[2] Auclair G, Weber M. Mechanisms of DNA methylation and demethylation in mammals. Biochimie, 2012, 94(11): 2202-2211. <\p>

[3] Watt F, Molloy PL. Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev, 1988, 2(9): 1136-1143. <\p>

[4] Zhu WG, Srinivasan K, Dai ZY, Duan WR, Druhan LJ, Ding HM, Yee L, Villalona-Calero MA, Plass C, Otterson GA. Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter. Mol Cell Biol, 2003, 23(12): 4056-4065. <\p>

[5] Strahl BD, Allis CD. The language of covalent histone modifications. Nature, 2000, 403(6765): 41-45. <\p>

[6] Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatin-binding modules interpret histone modi-fications: lessons from professional pocket pickers. Nat Struct Mol Biol, 2007, 14(11): 1025-1040. <\p>

[7] Shi Y, Whetstine JR. Dynamic regulation of histone lysine methylation by demethylases. Mol Cell, 2007, 25(1): 1-14. <\p>

[8] Martin C, Zhang Y. The diverse functions of histone ly-sine methylation. Nat Rev Mol Cell Biol, 2005, 6(11): 838-849. <\p>

[9] Kouzarides T. Chromatin modifications and their function. Cell, 2007, 128(4): 693-705. <\p>

[10] Skreka K, Schafferer S, Nat IR, Zywicki M, Salti A, Apostolova G, Griehl M, Rederstorff M, Dechant G, Hüt-tenhofer A. Identification of differentially expressed non-coding RNAs in embryonic stem cell neural differen-tiation. Nucleic Acids Res, 2012, 40(13): 6001-6015. <\p>

[11] Kaikkonen MU, Lam MTY, Glass CK. Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res, 2011, 90(3): 430-440. <\p>

[12] Mattick JS, Makunin IV. Non-coding RNA. Hum Mol Genet, 2006, 15(Suppl 1): R17-R29. <\p>

[13] Tuddenham L, Wheeler G, Ntounia-Fousara S, Waters J, Hajihosseini MK, Clark I, Dalmay T. The cartilage spe-cific microRNA-140 targets histone deacetylase 4 in mouse cells. Febs Lett, 2006, 580(17): 4214-4217. <\p>

[14] Fabbri M, Garzon R, Cimmino A, Liu ZF, Zanesi N, Cal-legari E, Liu SJ, Alder H, Costinean S, Fernan-dez-Cymering C, Volinia S, Guler G, Morrison CD, Chan KK, Marcucci G, Calin GA, Huebner K, Croce CM. Mi-croRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA, 2007, 104(40): 15805-15810. <\p>

[15] Kawasaki H, Taira K. Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature, 2004, 431(7005): 211-217. <\p>

[16] Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K, Hannon GJ. Developmentally regulated piRNA clusters implicate MILI in transposon control. Science, 2007, 316(5825): 744-747. <\p>

[17] Yang PK, Kuroda MI. Noncoding RNAs and intranuclear positioning in monoallelic gene expression. Cell, 2007, 128(4): 777-786. <\p>

[18] Volkmar M, Dedeurwaerder S, Cunha DA, Ndlovu MN, Defrance M, Deplus R, Calonne E, Volkmar U, Igoillo- Esteve M, Naamane N, Del Guerra S, Masini M, Bugliani M, Marchetti P, Cnop M, Eizirik DL, Fuks F. DNA me-thylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients. Embo J, 2012, 31(6): 1405-1426. <\p>

[19] Kuroda A, Rauch TA, Todorov I, Ku HT, Al-Abdullah IH, Kandeel F, Mullen Y, Pfeifer GP, Ferreri K. Insulin gene expression is regulated by DNA methylation. PloS ONE, 2009, 4(9): e6953. <\p>

[20] Yang BT, Dayeh TA, Kirkpatrick CL, Taneera J, Kumar R, Groop L, Wollheim CB, Nitert MD, Ling C. Insulin pro-moter DNA methylation correlates negatively with insulin gene exp