基因及其顺式调控元件在动物表型进化中的作用
收稿日期: 2013-10-07
修回日期: 2013-12-06
网络出版日期: 2014-05-28
基金资助
四川农业大学“双支”计划基金(编号2920200)和四川省教育厅“科研创新团队”基金资助
Role of genes and their cis-regulatory elements during animal morphological evolution
Received date: 2013-10-07
Revised date: 2013-12-06
Online published: 2014-05-28
孙博渊, 涂剑波, 李英, 杨明耀 . 基因及其顺式调控元件在动物表型进化中的作用[J]. 遗传, 2014 , 36(6) : 525 -535 . DOI: 10.3724/SP.J.1005.2014.0525
Cis-regulatory hypothesis is one of the most important theories in evolutionary developmental biology (evo-devo), which claims that evolution of cis-regulatory elements (CREs) plays a key role during evolution of morphology. However, an increasing number of experimental results show that cis-regulatory hypothesis alone is not far enough to explain the complexity of evo-devo processes. Other modifications, including mutations of protein coding, gene and genome duplications, and flexibility of homeodomains and CREs, also cause the morphological changes in animals. In this review, we retrospect the recent results of evolution of CREs and genes associated with CREs and discuss new methods and trends for research in evo-devo.
Key words： evo-devo; -regulatory element; gene; morphology
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