植物NBS类抗病基因的进化
收稿日期: 2014-06-19
网络出版日期: 2014-12-20
基金资助
国家自然科学基金项目(编号：31360050)资助
Evolution of plant NBS encoding disease resistance genes
Received date: 2014-06-19
Online published: 2014-12-20
NBS(Nucleotide-binding site)类抗病基因是植物中最重要的一类抗病基因, 其进化模式、结构特点和功能调控一直是抗病基因研究领域的热点。这类基因具有保守的结构域, 广泛存在于植物基因组中, 在不同植物基因组中数目差异较大且具有较低的表达量。此外, 同源NBS类抗病基因之间通过频繁的序列交换产生广泛的序列多样性, 且抗病基因位点具有较差的线性。依据基因之间序列交换的频率, 抗病基因可分为TypeⅠ和TypeⅡ两类。文章从抗病基因的结构、数量、分布、序列多样性、进化模式以及表达调控等方面进行了综述, 旨在为后续NBS类抗病基因的相关研究提供参考。
罗莎 . 植物NBS类抗病基因的进化[J]. 遗传, 2014 , 36(12) : 1219 -1225 . DOI: 10.3724/SP.J.1005.2014.1219
NBS (nucleotide-binding site) genes are a major class of disease resistance (R) genes in plants. Studies on their evolutionary pattern, structure characteristics and functional regulation have been always paid much attentions. NBS genes exist in a various plants by different copy numbers and low expression levels. They encode pro-teins containing conserved NBS domain and C-terminal leucine-rich repeats (LRRs). The NBS genes have frequent sequence exchanges among homologs and consequently show extensive diversity and poor synteny. Two types of NBS genes are distinguished based on their frequency of sequence exchanges. In this review, we summarize the latest progress of plant NBS encoding genes in terms of structure, number, evolutionary pattern, sequence diversity and distribution in genome, providing some insights into the further research on NBS genes in plant.
Key words： NBS encoding gene; evolutionary pattern; sequence diversity; synteny
[1] Hulbert SH, Webb CA, Smith SM, Sun Q. Resistance gene complexes: Evolution and utilization. Annu Rev Phytopathol, 2001, 39: 285–312.
[2] 庄军, 刘志昕. 植物抗病基因的进化. 遗传, 2004, 26(6): 962–968.
[3] Flor HH. Current status of the gene-for-gene concept. Annu Rev Phytopathol, 1971, 9: 275–296.
[4] Kuang H, Woo SS, Meyers BC, Nevo E, Michelmore RW. Multiple genetic processes result in heterogeneous rates of evolution within the major cluster disease resistance genes in lettuce. Plant Cell, 2004, 16(11): 2870–2894.
[5] Hammond-Kosack KE, Jones JDG. Plant disease resis¬tance genes. Annu Rev Plant Physiol Plant Mol Biol, 1997, 48: 575–607.
[6] Bai JF, Pennill LA, Ning JC, Lee SW, Ramalingam J, Webb CA, Zhao BY, Sun Q, Nelson JC, Leach JE, Hulbert SH. Diversity in nucleotide binding site-leucine-rich repeat genes in cereals. Genome Res, 2002, 12(12): 1871– 1884.
[7] Yue JX, Meyers BC, Chen JQ, Tian DC, Yang SH. Tracing the origin and evolutionary history of plant nucleo-tide-binding site-leucine-rich repeat (nbs-lrr) genes. New Phytol, 2012, 193(4): 1049–1063.
[8] Ameline-Torregrosa C, Wang BB, O'Bleness MS, Desh-pande S, Zhu H, Roe B, Young ND, Cannon SB. Identifi-cation and characterization of nucleotide-binding site-leucine- rich repeat genes in the model plant Medicago truncatula. Plant Physiol, 2008, 146(1): 5–21.
[9] Meyers BC, Kozik A, Griego A, Kuang H, Michelmore RW. Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis. Plant Cell, 2003, 15(4): 809–834.
[10] Yang SH, Zhang XH, Yue JX, Tian DC, Chen JQ. Recent duplications dominate NBS-encoding gene expansion in two woody species. Mol Genet Genomics, 2008, 280(3): 187–198.
[11] Lin X, Zhang Y, Kuang H, Chen JJ. Frequent loss of lineages and deficient duplications accounted for low copy number of disease resistance genes in Cucurbitaceae. BMC Genomics, 2013, 14: 335.
[12] Xu X, Pan SK, Cheng SF, Zhang B, Mu DS, Ni PX, Zhang GU, Yang S, Li RQ, Wang J, Orjeda G, Guzman F, Torres M, Lozano R, Ponce O, Martinez D, De la Cruz G, Chakrabarti SK, Patil VU, Skryabin KG, Kuznetsov BB, Ravin NV, Kolganova TV, Beletsky AV, Mardanov AV, Di Genova A, Bolser DM, Martin DMA, Li GC, Yang Y, Kuang H, Hu Q, Xiong XY, Bishop GJ, Sagredo B, Mejía N, Zagorski W, Gromadka R, Gawor J, Szczesny P, Huang S, Zhang ZH, Liang CB, He J, Li Y, He Y, Xu JF, Zhang YJ, Xie BY, Du YC, Qu DY, Bonierbale M, Ghislain M, Herrera Mdel R, Giuliano G, Pietrella M, Perrotta G, Facella P, O'Brien K, Feingold SE, Barreiro LE, Massa GA, Diambra L, Whitty BR, Vaillancourt B, Lin H, Massa AN, Geoffroy M, Lundback S, DellaPenna D, Buell CR, Sharma SK, Marshall DF, Waugh R, Bryan GJ, Destefanis M, Nagy I, Milbourne D, Thomson SJ, Fiers M, Jacobs JM, Nielsen KL, Sønderkaer M, Iovene M, Torres GA, Jiang JM, Veilleux RE, Bachem CWB, de Boer J, Borm T, Kloosterman B, van Eck H, Datema E, Hekkert BL, Goverse A, van Ham RCHJ, Visser RGF. Genome sequence and analysis of the tuber crop potato. Nature, 2011, 475(7355): 189–195.
[13] Xu Q, Chen LL, Ruan XA, Chen DJ, Zhu DA, Chen CL, Bertrand D, Jiao WB, Hao BH, Lyon MP, Chen JJ, Gao S, Xing F, Lan H, Chang JW, Ge XH, Lei Y, Hu Q, Miao Y, Wang L, Xiao SX, Biswas MK, Zeng WF, Guo F, Cao HB, Yang XM, Xu XW, Cheng YJ, Xu J, Liu JH, Luo OJ, Tang ZH, Guo WW, Kuang H, Zhang HY, Roose ML, Nagarajan N, Deng XX, Ruan YJ. The draft genome of sweet orange (citrus sinensis). Nat Genet, 2013, 45(1): 59–66.
[14] Kohler A, Rinaldi C, Duplessis S, Baucher M, Geelen D, Duchaussoy F, Meyers BC, Boerjan W, Martin F. Genome-wide identification of nbs resistance genes in Populus trichocarpa. Plant Mol Biol, 2008, 66(6): 619–636.
[15] Li J, Ding J, Zhang W, Zhang YL, Tang P, Chen JQ, Tian DC, Yang SH. Unique evolutionary pattern of numbers of gramineous NBS-LRR genes. Mol Genet Genomics, 2010, 283(5): 427–438.
[16] L
/
| 〈 |
|
〉 |
www.chinagene.cn
备案号：京ICP备09063187号-4
总访问:,今日访问:,当前在线:
