综述

植物Hippo信号通路研究进展

展开
  • 南开大学生命科学学院,天津市蛋白质科学重点实验室,天津 300071
张平平,硕士研究生,专业方向:植物生理与分子生物学。E-mail: zhangppsmile@163.com|龚清秋,博士,副教授,研究方向:胞内运输与植物发育。E-mail: gongq@nankai.edu.cn

收稿日期: 2017-02-28

  修回日期: 2017-04-28

  网络出版日期: 2017-05-08

基金资助

国家自然科学基金项目(31671419);南开大学中央高校基本科研业务费(63161201)

The emerging Hippo signaling pathway in plants

Expand
  • Tianjin Key Laboratory of Protein Sciences, College of Life Sciences, Nankai University, Tianjin 300071, China

Received date: 2017-02-28

  Revised date: 2017-04-28

  Online published: 2017-05-08

Supported by

the National Natural Science Foundation of China(31671419);the Fundamental Research Funds of the Central Universities(63161201)

摘要

植物器官大小如何决定是发育生物学的基本问题之一。Hippo信号通路是动物中最重要的负调控器官大小的信号通路。近期研究表明,植物中可能也存在Hippo信号通路。本文回顾了植物中已经发现的两个Hippo信号通路的核心蛋白——Ste20/Hippo同源蛋白SIK1与MOB1/Mats同源蛋白MOB1,着重论述了SIK1和MOB1在调控植物生长发育中的作用,并对未来建立一条完整的植物Hippo信号通路进行了展望。

本文引用格式

张平平,佟鑫,张天乐,黎子琛,龚清秋 . 植物Hippo信号通路研究进展[J]. 遗传, 2017 , 39(7) : 568 -575 . DOI: 10.16288/j.yczz.17-067

Abstract

How the organ size is determined is a fundamental question in developmental biology. The metazoan Hippo signaling pathway is well established to negatively regulate organ sizes. Recent studies in plants have started to shape an emerging Hippo signaling pathway. In this review, we summarize the studies in the past decade on the two known components of plant Hippo signaling pathway, the Ste20/Hippo homolog SIK1, and the MOB1/Mats homolog MOB1, with a focus on their developmental functions. Then we envision future discoveries that may shape a complete Hippo signaling pathway in plants.

参考文献

[1] Vanhaeren H, Inzé D, Gonzalez N. Plant growth beyond limits. Trends Plant Sci, 2016, 21(2): 102-109.
[2] Gonzalez N, Vanhaeren H, Inzé D. Leaf size control: complex coordination of cell division and expansion. Trend Plant Sci, 2012, 17(6): 332-340.
[3] Tsukaya H. Leaf development. Arabidopsis Book, 2013, 11: e0163.
[4] Andriankaja M, Dhondt S, De Bodt S, Vanhaeren H, Coppens F, De Milde L, Mühlenbock P, Skirycz A, Gonzalez N, Beemster GTS, Inzé D. Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so- gradual process. Dev Cell, 2012, 22(1): 64-78.
[5] Massonnet C, Tisne S, Radziejwoski A, Vile D, De Veylder L, Dauzat M, Granier C. New insights into the control of endoreduplication: endoreduplication could be driven by organ growth in Arabidopsis leaves. Plant Physiol, 2011, 157(4): 2044-2055.
[6] Hepworth J, Lenhard M. Regulation of plant lateral-organ growth by modulating cell number and size. Curr Opin Plant Biol, 2014, 17: 36-42.
[7] González N, Inzé D. Molecular systems governing leaf growth: from genes to networks. J Exp Bot, 2015, 66(4): 1045-1054.
[8] Li N, Li YH. Signaling pathways of seed size control in plants. Curr Opin Plant Biol, 2016, 33: 23-32.
[9] Wang HF, Wang HW, Yang SX, He YK. Research progress of regulators of organ size in plants. Plant Physiol J, 2013, 49(5): 437-444.
[9] 王洪峰, 王宏伟, 杨素欣, 何玉科. 植物器官大小调控因子研究进展. 植物生理学报, 2013, 49(5): 437-444.
[10] Horváth BM, Magyar Z, Zhang YX, Hamburger AW, Bakó L, Visser RGF, Bachem CWB, B?gre L. EBP1 regulates organ size through cell growth and proliferation in plants. EMBO J, 2006, 25(20): 4909-4920.
[11] Hu YX, Xie Q, Chua NH. The Arabidopsis auxin- inducible gene ARGOS controls lateral organ size. Plant Cell, 2003, 15(9): 1951-1961.
[12] Feng GP, Qin ZX, Yan JZ, Zhang XR, Hu YX. Arabidopsis ORGAN SIZE RELATED1 regulates organ growth and final organ size in orchestration with ARGOS and ARL. New Phytologist, 2011, 191(3): 635-646.
[13] Hu Y X, Poh H M, Chua N H. The Arabidopsis ARGOS- LIKE gene regulates cell expansion during organ growth. Plant J, 2006, 47(1): 1-9.
[14] Qin ZX, Zhang XR, Zhang X, Xin W, Li J, Hu YX. The Arabidopsis transcription factor IIB-related protein BRP4 is involved in the regulation of mitotic cell-cycle progression during male gametogenesis. J Exp Bot, 2014, 65(9): 2521-2531.
[15] Okushima Y, Overvoorde PJ, Arima K, Alonso JM, Chan A, Chang C, Ecker JR, Hughes B, Lui A, Nguyen D, Onodera C, Quach
文章导航

/