时间生物学—2017年诺贝尔生理或医学奖解读
收稿日期: 2017-12-04
修回日期: 2017-12-22
网络出版日期: 2017-12-27
基金资助
国家自然科学基金(编号：31570285),教育部新世纪优秀人才支持计划(编号：NCET-13-0771),河北省教育厅研究生创新资助项目(编号：CXZZBS2017093)和河北师范大学大学生创新创业计划(编号：201710094011)资助
Chronobiology—2017 Nobel Prize in Physiology or Medicine
Received date: 2017-12-04
Revised date: 2017-12-22
Online published: 2017-12-27
Supported by
[Supported by the National Natural Science Foundation of China (No. 31570285), Program for New Century Excellent Talents in University (No. NCET-13-0771), Graduate Student Innovation Fund of Hebei Province (No. CXZZBS2017093), and Hebei Normal University Undergraduate Student Training Grant (No. 201710094011)]
袁力, 李艺柔, 徐小冬 . 时间生物学—2017年诺贝尔生理或医学奖解读[J]. 遗传, 2018 , 40(1) : 1 -11 . DOI: 10.16288/j.yczz.17-397
Chronobiology is a field of biology that examines the generation of biological rhythms in various creatures and in many parts of body, and their adaptive fitness to solar- and lunar-related periodic phenomena. The synchronization of internal circadian clocks with external timing signals confers accurate phase response and tissue homeostasis. Herein we state a series of studies on circadian rhythms and introduce the brief history of chronobiology. We also present a detailed timeline of the discoveries on molecular mechanisms controlling circadian rhythm in Drosophila, which was awarded the 2017 Nobel Prize in Physiology or Medicine. The latest findings and new perspectives are further summarized to indicate the significance of circadian research.
Key words： chronobiology; biological clock; circadian rhythms; tissue homeostasis; fitness
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