猪乳头性状生理学和遗传学研究进展

周李生, 赵为民, 涂枫, 吴云鹤, 任守文, 方晓敏

doi:10.16288/j.yczz.18-336

遗传 >

2019 , Vol. 41 >Issue 5: 384 - 390

DOI: https://doi.org/10.16288/j.yczz.18-336

综述

猪乳头性状生理学和遗传学研究进展

展开

江苏省农业科学院畜牧研究所,江苏省农业种质资源保护与利用平台,南京 210014

周李生,博士,助理研究员,研究方向：猪数量性状遗传解析。E-mail: zls123668@qq.com

收稿日期: 2018-12-12

修回日期: 2019-04-22

网络出版日期: 2019-05-11

基金资助

国家生猪现代产业技术体系南京综合试验站项目(CARS-35);江苏省农业重大新品种创制项目(PZCZ201733);江苏省农业科学院科研专项(ZX(18)7006);江苏省博士后科研资助计划(2018K059B)

收起

Physiology and genetics research progress of teat traits in pigs

Expand

Jiangsu Germplasm Resources Protection and Utilization Platform, Institute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China

Received date: 2018-12-12

Revised date: 2019-04-22

Online published: 2019-05-11

Supported by

National Pig Industrial Technology System Nanjing Experimental Station(CARS-35);Jiangsu Agricultural Major New Breed Creation Project(PZCZ201733);Special Scientific Research Fund of Jiangsu Academy of Agricultural Sciences(ZX(18)7006);Jiangsu Post-doctoral research Funding(2018K059B)

Fold

摘要

猪乳头性状属于繁殖性状,直接影响母猪哺乳率和仔猪成活率,是种猪遗传改良的重要指标,揭示其遗传机理对提高种猪繁殖性能具有重要意义。猪乳头性状复杂多样,包括乳头数、乳头类型、乳头位置分布和波动不对称性现象等,但其遗传机制尚不清晰。本文对猪乳头及乳腺的形成与发育过程、猪乳头性状调控基因数量性状位点(quantitative trait locus, QTL)定位和候选基因等生理学和遗传学方面的研究进展进行了综述,旨在为今后鉴别影响猪乳头性状的因果突变和主效基因,揭示猪乳头在胚胎发育过程中产生数目、类型和位置差异的复杂遗传机制提供新的视角。

关键词： 猪; 乳头性状; 遗传研究

本文引用格式

周李生, 赵为民, 涂枫, 吴云鹤, 任守文, 方晓敏 . 猪乳头性状生理学和遗传学研究进展[J]. 遗传, 2019 , 41(5) : 384 -390 . DOI: 10.16288/j.yczz.18-336

Abstract

The pig teat traits are important indices of genetic improvement in pig breeding, which belong to reproductive traits and can directly affect the sows lactation rate and piglet survival rate. Understanding the genetic mechanism underlying the variation of teat traits is of immense value for the improvement of pig reproductive performance. However, the genetic mechanism underlying teat traits (including teat number, type, location distribution, and fluctuating asymmetry) remains elusive. In this review, we summarize the studies on physiology and genetics of teat traits in pigs, including the development process of the mammary gland, the QTL mapping, and candidate gene researches. This review aims to provide a new perspective for the identification of causal mutations and major genes affecting the teat traits and revealing the complex genetic mechanism of the differences in teat number, type and location distribution during embryonic development in pigs.

Key words： pig; teat traits; genetic research

参考文献

[1]

Verardo LL, Silva FF, Lopes MS, Madsen O, Bastiaansen JW, Knol EF, Kelly M, Varona L, Lopes PS, Guimar?es SE . Revealing new candidate genes for reproductive traits in pigs: combining bayesian GWAS and functional pathways. Genet Sel Evol, 2016,48:9.

[2]

Felleki M, Lundeheim N . Genetic heteroscedasticity of teat count in pigs. J Anim Breed Genet, 2015,132(5):392-398.

[3]

Robinson GW . Cooperation of signalling pathways in embryonic mammary gland development. Nat Rev Genet, 2007,8(12):963-972.

[4]

Roarty K, Serra R . Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth. Development, 2007,134(21):3929-3939.

[5]

Eblaghie MC, Song SJ, Kim JY, Akita K, Tickle C, Jung HS . Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos. J Anat, 2004,205(1):1-13.

[6]

Veltmaat JM, Relaix F, Le LT, Kratochwil K, Sala FG, van Veelen W, Rice R, Spencer-Dene B, Mailleux AA, Rice DP . Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes. Development, 2006,133(12):2325-2335.

[7]

Mailleux AA, Savona-Baron B, Ndiaye D, Savona-Baron C, Itoh N, Kato S, Dickson C, Thiery JP, Bellusci S . Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development, 2002,129(1):53-60.

[8]

Howard B, Panchal H, McCarthy A, Ashworth A . Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification. Genes Dev, 2005,19(17):2078-2090.

[9]

Buono KD, Robinson GW, Martin C, Shi S, Stanley P, Tanigaki K, Honjo T, Hennighausen L . The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy. Dev Biol, 2006,293(2):565-580.

[10]

Heckman BM, Chakravarty G, Vargo-Gogola T, Gonzales- Rimbau M, Hadsell DL, Lee AV, Settleman J, Rosen JM . Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol, 2007,309(1):137-149.

[11]

Yang ZC, Zhou ZX, Li Z, Dong YZ . Anatomical and histological characteristics of in-verted papilla of pig. Acta Vet Et Zootech Sin, 1999,30(6):519-524.

[11]

杨志春, 周忠孝, 李照, 董玉珍 . 猪翻乳头的解剖组织学特征的研究与探讨. 畜牧兽医学报, 1999,30(6):519-524.

[12]

Nikitin SV, Kniazev SP, Ermolaev VI . Model of genetic control of the number and location of nipples in domestic pig. Genetika, 2012,48(11):1128-1140.

[13]

Fernández A, Toro M, Rodríguez C, Silió L . Heterosis and epistasis for teat number and fluctuating asymmetry in crosses between Jiaxing and Iberian pigs. Heredity

Options

文章导航

〈

〉

www.chinagene.cn
备案号：京ICP备09063187号-4
总访问:,今日访问:,当前在线:

模态框（Modal）标题

摘要

本文引用格式

Abstract

参考文献