细胞外囊泡的研究进展

doi:10.16288/j.yczz.24-371

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Hereditas(Beijing) ›› 2025, Vol. 47 ›› Issue (10): 1078-1098.doi: 10.16288/j.yczz.24-371

• Review • Previous Articles Next Articles

Progress on extracellular vesicles

Jiaqiang Chen¹^,²(), Mei Ding¹^,²()

1. Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
2. University of Chinese Academy of Sciences, Beijing 100093, China

Received:2025-04-11 Revised:2025-06-11 Online:2025-10-20 Published:2025-10-17
Contact: Mei Ding E-mail:jiaqiang.chen@genetics.ac.cn;mding@genetics.ac.cn
Supported by:
National Natural Science Foundation of China(31921002)

Abstract

Abstract:

Extracellular vesicles are membrane-enclosed structures released by cells into the extracellular space, containing various biomolecules such as proteins, nucleic acids, and lipids. Extracellular vesicles exhibit broad cellular origins, diverse types, and high heterogeneity. They are involved in intercellular material transport, mediate intercellular communication, and play important roles in various cellular biological processes, including cell proliferation, apoptosis, and migration. This review summarizes recent advances in research on the isolation and identification, biogenesis mechanisms, and fate of extracellular vesicles, aiming to provide a reference for advancing research in this field.

Key words: extracellular vesicles, characteristics, biogenesis, fate

Jiaqiang Chen, Mei Ding. Progress on extracellular vesicles[J]. Hereditas(Beijing), 2025, 47(10): 1078-1098.

Figures/Tables 4

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