遗传 ›› 2020, Vol. 42 ›› Issue (2): 145-152.doi: 10.16288/j.yczz.19-253

• 综述 • 上一篇    下一篇

基因组选择在猪杂交育种中的应用

杨岸奇1,2,3(), 陈斌1,3(), 冉茂良1,3(), 杨广民2, 曾诚2   

  1. 1. 湖南农业大学动物科学技术学院,长沙 410128
    2. 湖南美可达生物资源股份有限公司,长沙 410331
    3. 畜禽遗传改良湖南省重点实验室,长沙 410128
  • 收稿日期:2019-08-28 修回日期:2020-02-08 出版日期:2020-02-17 发布日期:2020-02-19
  • 基金资助:
    国家重点研发计划项目(2017YFD0501504);国家重点研发计划项目(2016YFD0501308);国家现代农业产业技术体系建设专项资金(CARS-36)

The application of genomic selection in pig cross breeding

Yang Anqi1,2,3(), Chen Bin1,3(), Ran Maoliang1,3(), Yang Guangmin2, Zeng Cheng2   

  1. 1. College of Animal Science & Technology, Hunan Agricultural University, Changsha 410128, China
    2. Hunan Micolta Bioresource Inc, Changsha 410331, China
    3. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China
  • Received:2019-08-28 Revised:2020-02-08 Online:2020-02-17 Published:2020-02-19
  • Supported by:
    the National Key Research and Development(2017YFD0501504);the National Key Research and Development(2016YFD0501308);Special Fund for the Industrial Technology System Construction of Modern Agriculture(CARS-36)

摘要:

基因组选择是指在全基因组范围内通过基因组中大量的标记信息估计出个体全基因组范围的育种值,可进一步提升育种效率和准确性,目前在猪纯繁育种中得到广泛应用。但有研究表明,现有的基因组选择方法在猪杂交育种上的应用效果并不理想,在跨群体条件下预测准确性极低。杂交作为养猪业中最为广泛的育种手段之一,通过结合基因组选择理论进一步提升猪的生产性能,具有重要的经济和研究价值。本文综述了基因组选择的发展及其在猪育种中的应用现状,并结合国内外猪杂交育种的方式,分析了目前基因组选择方法在猪杂交育种应用方面的不足,旨在为未来基因组选择在猪杂交育种中的合理应用提供参考。

关键词: 基因组选择, 猪, 杂交育种, 统计模型

Abstract:

Genomic selection is a form of marker-assisted selection in which genetic markers covering the entire genome are used so that all quantitative trait loci are in linkage disequilibrium with at least one marker. Genomic selection improves the efficiency and accuracy of breeding and it is widely used in purebred breeding across many animal species. However, some studies indicate that the accuracy of genome selection in cross breeding needs to be improved,especially in cross population. As one of the most extensive breeding methods employed in the swine industry, cross breeding has significant, potential research and economic value to further improve its performance by combining with genomic selection. In this review, we summarize the application of genomic selection in pigs, and elucidate the genomic selection deficiencies in breeding hybrid pigs. This review will also provide valuable insights for the future application and improvement of genomic selection in pig cross breeding.

Key words: genomic selection, swine, cross breeding, statistical genetics