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miRNA参与调控植物应答干旱、盐胁迫的研究进展

李皓栋1,2,孟佳欣2,王滑1,董宁光2   

  1. 1. 华中农业大学园艺林学学院,果蔬园艺作物种质创新与利用全国重点实验室,武汉 430070

    2. 北京市农林科学院林业果树研究所,农业农村部华北地区园艺作物生物学与种质创制重点实验室,北京市落叶果树工程技术研究中心,北京 100093
  • 出版日期:2025-11-18 发布日期:2025-11-18
  • 基金资助:
    国家自然科学基金项目(编号:32401631)和北京市农林科学院科技创新能力专项(编号:KJCX20251401)资助

Progress on miRNAs involved in regulating plant responses to drought and salt stresses

Haodong Li1,2, Jiaxin Meng2, Hua Wang1, Ningguang Dong2   

  1. 1. National Key Laboratory for Germplasm Innovation and Utilization of Horticultural Crops, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan 430070, China

    2. Beijing Engineering Research Center for Deciduous Fruit Trees, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China), Ministry of Agriculture and Rural Affairs, Institute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100093, China
  • Published:2025-11-18 Online:2025-11-18

摘要: 干旱与盐胁迫是制约植物生长发育与繁殖的常见非生物胁迫。为此,植物进化出了复杂的分子调控网络,使其能够敏锐感知外界胁迫并快速启动应答。其中,microRNA(miRNA)在这一过程中扮演关键角色。植物miRNA是一类长约20~24 nt的非编码小分子RNA,通过转录后水平切割靶基因或抑制其翻译,从而参与调控植物应答逆境胁迫。近年来,随着高通量测序技术的快速发展与广泛应用,大量参与干旱与盐胁迫应答的miRNA被鉴定,其功能及作用机制也逐渐被揭示。本文系统综述了miRNA参与调控植物干旱、盐胁迫的分子机制,全面展示了miRNA调控植物抗旱耐盐的共性及特异性机制,并总结归纳了可作为生物育种潜在靶点的miRNA,旨在为植物miRNA的深入研究提供参考,也为植物抗旱耐盐遗传改良中的实际应用提供理论依据与前沿视角。

关键词: 植物, micoRNA, 干旱胁迫, 盐胁迫

Abstract: Drought and salt stress are common abiotic constraints that limit plant growth, development, and reproduction. In response, plants have evolved complex molecular regulatory networks enabling them to perceive external stresses acutely and initiate rapid responses. Among these, microRNAs (miRNAs) play a pivotal role. Plant miRNAs are a class of non-coding small RNAs approximately 20-24 nucleotides in length, which exert their stress-responsive functions by cleaving target genes at the post-transcriptional level or inhibiting their translation. In recent years, with the rapid development and widespread application of high-throughput sequencing technology, a large number of miRNAs involved in drought and salt stress responses have been identified, and their functions and mechanisms of action have been gradually elucidated. In this review, we systematically summarize the molecular mechanisms by which miRNAs participate in regulating plant responses to drought and salt stress, comprehensively illustrating the common and specific mechanisms of miRNA-mediated drought resistance and salt tolerance in plants. We also compile and discuss the miRNAs that could serve as potential targets for biological breeding. The aim is to provide a reference for in-depth research on plant miRNAs, as well as a theoretical basis and forward-looking perspectives for their practical application in the genetic improvement of drought resistance and salt tolerance in plants.

Key words: plants; microRNA, drought stress, salt stress