H-FABP、MC4R、ADD1基因多态性在3个猪群中分布及其与肌内脂肪和背膘的相关研究

遗传 ›› 2006, Vol. 28 ›› Issue (2): 159-164.

H-FABP、MC4R、ADD1基因多态性在3个猪群中分布及其与肌内脂肪和背膘的相关研究

李长龙^1;3;潘玉春¹

1. 上海交通大学农业与生物学院，上海 201101；2. 苏州市苏太猪育种中心，苏州 215000；3. 华东理工大学药学院，上海 200237

收稿日期:2005-04-17 修回日期:2005-11-04 出版日期:2006-02-10 发布日期:2006-02-10
通讯作者: 潘玉春

Distributions of Polymorphism of ADD1, MC4R, H-FABP Gene, Associated with IMF and BF in 3 Populations in Pig

LI Chang-Long^{1, 3}, PAN Yu-Chun¹^①, MENG He¹, WANG Zi-Lin²,

HUANG Xue-Gen²

1.Department of Animal Science, Shanghai Jiaotong University, shanghai 201101, China;
2.Center of Sutai Pig Breeding, Suzhou 215000, China;3.School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Received:2005-04-17 Revised:2005-11-04 Online:2006-02-10 Published:2006-02-10
Contact: PAN Yu-Chun

摘要/Abstract

摘要：

具有不同遗传特性的猪种具有不同的肉质性状。尤其是地方品种和引进品种间在肉质性状存在极大的差异。在已有的研究中H-FABP，MC4R，ADD1基因同肌内脂肪或背膘相关。利用梅山猪、苏太猪和杜×长×大猪为试验动物，研究上述3个基因的多态性分布和多态性同肌内脂肪和背膘的相关性。结果表明：3个基因的多态性分布在不同猪种间存在极显著的差异，这种差异可能是肌内脂肪（IMF）或背膘（BF）不同的主要原因之一。连锁分析表明：H-FABP和ADD1基因多态性同IMF有显著的相关，但是同BF没有显著的相关；MC4R基因的多态性同IMF和BF都有显著相关性。说明：H-FABP和ADD1基因多态性有可能应用到提高IMF，同时不影响BF的育种实践中。

关键词: H-FABP, MC4R, ADD1, 肌内脂肪, 背膘

Abstract:

Different breeds of pigs varied in traits of meat quality, especially between local abroad varieties. Intramuscular fat content (IMF) and back fat thickness (BF) have extra difference between Chinese breeds and foreign breeds. We have known that polymorphism of H-FABP, MC4R and ADD1 gene associated relation with IMF or BF in recent research. The Meishan, Sutai and Duroc×Landrace×Yorkshair become experimental animal in this research. Result show three breeds have different IMF and BF because different distributions of polymorphism three genes. Meishan has particular genetic background, so it should be protected. The results of associated analysis show that the polymorphism of three genes was associated traits of IMF and BF, polymorphism of MC4R gene was not associated traits BF. The molecular marker can apply to pig breeding by molecular marker-assisted selection （MAS）.

中图分类号:

S828

李长龙，潘玉春. H-FABP、MC4R、ADD1基因多态性在3个猪群中分布及其与肌内脂肪和背膘的相关研究

[J]. 遗传, 2006, 28(2): 159-164.

LI Chang-Long, PAN Yu-Chun, MENG He, WANG Zi-Lin, HUANG Xue-Gen. Distributions of Polymorphism of ADD1, MC4R, H-FABP Gene, Associated with IMF and BF in 3 Populations in Pig[J]. HEREDITAS, 2006, 28(2): 159-164.

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