遗传 ›› 2006, Vol. 28 ›› Issue (7): 893-898.

• 专论与综述 • 上一篇    下一篇

鸡MHC与传染性疾病遗传抗性的相关性研究进展

李国勤;卢立志;王得前;沈军达;陶争荣;赵爱珍;原爱平   

  1. 浙江省农业科学院畜牧兽医研究所,杭州310021
  • 收稿日期:2005-07-01 修回日期:2005-10-08 出版日期:2006-07-10 发布日期:2006-07-10
  • 通讯作者: 卢立志

Advance in Association of Major Histocompatibility Complex(MHC) Gene Polymorphisms with Resistance Character to Infectious Disease in Chicks

LI Guo-Qin, LU Li-Zhi, WANG De-Qian, SHEN Jun-Da, TAO Zheng-Rong,
ZHAO Ai-Zhen, YUAN Ai-Ping   

  1. Institute of Animal Science and Veterinary Medicine, Zhejiang Academy of Agricultural Science, Hangzhou 310021, China
  • Received:2005-07-01 Revised:2005-10-08 Online:2006-07-10 Published:2006-07-10
  • Contact: LU Li-Zhi

摘要: 鸡是我国主要的家禽品种,抗病分子育种在鸡的疾病尤其是传染病控制中有着重要地位,抗性基因选择是其技术关键。鸡主要组织相容性复合体(MHC)基因具有高度多态性,与多种传染性疾病抗性紧密相关,受到家禽育种专家的高度关注。文章介绍国外有关鸡MHC与传染性疾病抗性的相关性及抗性基因研究进展,并展望其在鸡抗病育种中的应用前景。

关键词: 鸡, 主要组织相容性复合体(MHC), 抗病性状

Abstract: Chick is a main farming breed in China. With the development of intensive feeding in chick, resistance molecular breeding plays a more and more important role in the control of diseases, especial infectious diseases. The choice of genes for disease resistance is the key technology of resistance molecular breeding. The MHC is of great interest to poultry breeding scientist for the extraordinary polymorphism and close relation with resistance character to infectious disease. The article gives a detail introduction about the association of the MHC gene polymorphisms with resistance characters to infectious diseases in chicken and prospects the future of application of the MHC in resistance molecular breeding of chicken.

Key words: major histocompatibility complex(MHC), chicken, disease resistance character

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