遗传 ›› 2021, Vol. 43 ›› Issue (10): 930-937.doi: 10.16288/j.yczz.21-215

• 综述 • 上一篇    下一篇

组学大数据和医学人工智能

王昕玥1,2,3(), 渠鸿竹1,2,3(), 方向东1,2,3()   

  1. 1. 中国科学院北京基因组研究所(国家生物信息中心),中国科学院基因组科学与信息重点实验室,北京 100101
    2. 中国科学院大学,北京 100049
    3. 中国科学院北京基因组研究所(国家生物信息中心),基因组与精准医学检测技术北京市重点实验室,北京 100101;
  • 收稿日期:2021-06-18 修回日期:2021-08-31 出版日期:2021-10-20 发布日期:2021-10-08
  • 通讯作者: 渠鸿竹,方向东 E-mail:wangxinyue2019d@big.ac.cn;quhongzhu@big.ac.cn;fangxd@big.ac.cn
  • 作者简介:王昕玥,在读博士研究生,研究方向:基因组学。E-mail: wangxinyue2019d@big.ac.cn
  • 基金资助:
    科技部重点研发计划资助编号(2020YFC2003405);科技部重点研发计划资助编号(2016YFC0901700);科技部重点研发计划资助编号(2018YFC0910700)

Omics big data and medical artificial intelligence

Xinyue Wang1,2,3(), Hongzhu Qu1,2,3(), Xiangdong Fang1,2,3()   

  1. 1. CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences/China National Center for Bioinformation, Beijing 100101, China
    2. University of Chinese Academy of Sciences, Beijing 100049, China
    3. Beijing Key Laboratory of Genome and Precision Medicine Technologies, Beijing Institute of Genomics, Chinese Academy of Sciences/China National Center for Bioinformation, Beijing 100101, China
  • Received:2021-06-18 Revised:2021-08-31 Online:2021-10-20 Published:2021-10-08
  • Contact: Qu Hongzhu,Fang Xiangdong E-mail:wangxinyue2019d@big.ac.cn;quhongzhu@big.ac.cn;fangxd@big.ac.cn
  • Supported by:
    Supported by the National Key Research and Development Project of the Ministry of Science and Technology of the People’s Republic of China Nos(2020YFC2003405);Supported by the National Key Research and Development Project of the Ministry of Science and Technology of the People’s Republic of China Nos(2016YFC0901700);Supported by the National Key Research and Development Project of the Ministry of Science and Technology of the People’s Republic of China Nos(2018YFC0910700)

摘要:

随着高通量测序技术和计算机科学的飞速发展,组学数据量指数倍增长,多组学分析优势逐渐显现,人工智能应用也愈加广泛。本文介绍了近年来多组学数据分析和人工智能各自在医学领域的应用进展,同时也介绍了两者相结合应用的案例以及优势,最后简单阐述多组学分析和人工智能在现阶段面临的挑战,旨在为医学行业提供新的研究思路,助推精准医学发展应用。

关键词: 多组学, 人工智能, 医学, 精准医学

Abstract:

With the rapid development of high-throughput sequencing technology and computer science, the amount of large omics data has increased exponentially, the advantages of multi-omics analysis have gradually emerged, and the application of artificial intelligence has become more and more extensive. In this review, we introduce the application progress of multi-omics data analysis and artificial intelligence in the medical field in recent years, and also show the cases and advantages of their combined application. Finally, we briefly explain the current challenges of multi-omics analysis and artificial intelligence in order to provide new research ideas for the medical industry and to promote the development and application of precision medicine.

Key words: multi-omics, artificial intelligence, medicine, precision medicine