精子功能相关的蛋白质调控受精过程的研究进展

doi:10.3724/SP.J.1005.2014.0747

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HEREDITAS(Beijing) ›› 2014, Vol. 36 ›› Issue (8): 747-755.doi: 10.3724/SP.J.1005.2014.0747

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The progress of sperm functional proteins regulating the process of fertilization

Zhilin Chen¹, Meiying Feng¹, Yuming Chen¹, Hengxi Wei¹, Li Li¹, Tongshan Wu², Shouquan Zhang¹

1. National Engineering Research Center For Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China;
2. Dongguan Institute of Animal Science, Dongguan 523086, China

Received:2014-03-22 Online:2014-08-20 Published:2013-07-19

Abstract

Abstract: The process of mammalian fertilization involves a series of sperm functional activities, including the sperm transportation, hyperactivation and capacitation, acrosome reaction and sperm-egg fusion, etc. The semen proteins play indispensable roles in these processes, and they are closely associated with the fecundity of males. So these proteins can be biomarkers to evaluate the fertilization capacity of mammalian semen. In this review, we mainly introduce some semen proteins relevant to spermatozoa functions and illustrate their important regulatory roles on the fertilization processes, involving spermatozoa motility, capacitation, acrosome reaction, penetrating the zona pellucida and sperm-egg fusion, etc. Moreover, their potential applications in the evaluation of heredity in livestock are also summarized.

Key words: fertilization, spermatozoa, protein, biomarkers, fecundity

Zhilin Chen, Meiying Feng, Yuming Chen, Hengxi Wei, Li Li, Tongshan Wu, Shouquan Zhang. The progress of sperm functional proteins regulating the process of fertilization[J]. HEREDITAS(Beijing), 2014, 36(8): 747-755.

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