藏猪繁殖性状多基因效应分析
收稿日期: 2009-09-07
修回日期: 2009-11-30
网络出版日期: 2010-05-15
基金资助
国家科技支撑项目(编号：2008BADB2B01)和西藏自治区科技计划项目资助
Effects of multi-genes for reproductive traits in Tibet pig
Received date: 2009-09-07
Revised date: 2009-11-30
Online published: 2010-05-15
藏猪是我国特有的高原型地方猪种, 具有适应高海拔恶劣气候环境、抗病、耐粗、肉质鲜美等特点, 但繁殖力低。文章以促卵泡素b亚基(FSHb)、雌激素受体(ESR)、促乳素受体(PRLR)和视黄醛结合蛋白4(RBP4)等基因作为繁殖性状主要候选基因, 测定76头藏猪的基因型, 分析单基因和多基因合并对繁殖性状的影响效应。结果说明, 在藏猪群体中, FSHb、ESR和PRLR基因不同基因型繁殖性状差异显著, 优良基因型分别为BB、BB和AA。藏猪RBP4基因只有2种基因型, 对繁殖性状影响不显著。FSHb-ESR-PRLR基因的合并优良基因型为BB-BB-AA, 多基因聚合效应高于单基因效应。
刘轩，强巴央宗，王强，凌遥，辜雪冬，吴克亮，张浩 . 藏猪繁殖性状多基因效应分析[J]. 遗传, 2010 , 32(5) : 480 -485 . DOI: 10.3724/SP.J.1005.2010.00480
Tibet pig is a unique native breed in the plateau of China, which has good adaptation to the harsh climate of high land and resistance to diseases and crude feeding. However, its reproductive rate is low. The objectives of this study were to search for the polymorphisms of estrogen receptor (ESR), follicle-stimulating hormone (FSHb), prolactin receptor (PRLR), and retinol binding protein 4 (RBP4) in Tibet pig and to analyze the effects of these variants and their combination genotypes on reproductive traits. The results showed that the effects of FSHb, ESR, and PRLR genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively. There were two genotypes for RBP4 gene in Tibet pig, which did not have significant effect on the reproductive traits. The optical genotype of FSHb-ESR-PRLR is BB-BB-AA, which is more effective on reproductive traits than any single gene in Tibet pig.
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