遗传 ›› 2002, Vol. 24 ›› Issue (2): 200-202.

• 论文 • 上一篇    下一篇

双链RNA干涉技术(RNAi)在不同生物中应用的研究进展

韩蓓1;王秀敏1;顾学范1;2 HAN Bei1;WANG Xiu-min1;GU Xue-fan1;2   

  1. 1.上海第二医科大学附属新华医院分子医学实验室,上海 200092; 2.上海市儿科医学研究所,上海 200092 1.Molecular Biology Laboratory of Xinhua Hospital Shanghai 200092,China; 2.Pediatric Institute for Research of Shanghai Shanghai 200092,China
  • 收稿日期:1900-01-01 出版日期:2002-04-10 发布日期:2002-04-10

Double Stranded RNA (RNA inteference RNAi) in Different Creatures

  • Received:1900-01-01 Online:2002-04-10 Published:2002-04-10

摘要: 双链RNA(double~stranded RNA dsRNA )干涉技术可通过降解靶基因的mRNA进行基因干涉,是研究多种生物基因功能的有效手段,目前已在拟南芥、秀丽新小杆线虫、黑腹果蝇、斑马鱼和小鼠等生物中应用,本文拟就其应用特点进行综述。
Abstract:Doublestranded RNA could degrade mRNA of target gene.It is a useful way for studying gene function.It is used widely in different creatures,such as Arabidopsis thaliana,Caenorhabditis elegans,Drosophila melanogaster,Zebrafish,Mouse.This review is mainly related to the application of dsRNA in recent years

关键词: doublestranded RNA, gene inteference, 基因功能
Key words,
双链RNA, 基因干涉