遗传 ›› 2003, Vol. 25 ›› Issue (1): 107-112.

• 论文 • 上一篇    下一篇

植物生物反应器生产药物蛋白的前景

肖乃仲1;白云峰1;刘锦秀2;王兴智1   

  1. 1.东北师范大学遗传与细胞研究所,长春 130024;2.北京华大基因研究中心,北京 101300
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2003-02-10 发布日期:2003-02-10

Plants as Bioreactor for the Production of Pharmaceutical Proteins

XIAO Nai-Zhong1;BAI Yun-Feng1;LIU Jin-Xiu2;WANG Xing-Zhi1   

  1. 1.Institute of Genetics & Cytology,Northeast Normal University,Changchun 130024,China;
    2.Beijing Genomics Institute,Genomics & Bioinformatics Center,Chinese Academy of Science,Beijing 101300,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2003-02-10 Published:2003-02-10

摘要: 转基因植物作为生物反应器生产重要的药用蛋白,如抗体、血液替代品和疫苗,为健康保健和科学研究提供充足的生物药物,满足人们日益增长的需要。本文综述了这一领域的研究进展以及商业化前景。

关键词: 转基因植物, 生物反应器, 重组蛋白, 生物药物

Abstract: Transgenic plant as bioreactor has been used to produce recombinant proteins for medicinal purposes,including mammalian antibodies,blood substitutes and vaccines.As the demand for biopharmaceuticals is expected to increase,transgenic plants have the potential to provide virtually unlimited quantities of proteins for use as tools in both human health care and the bioscience.This paper reviews the recent developments in this field and the prospect of commercial applications.