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HEREDITAS(Beijing) ›› 2015, Vol. 37 ›› Issue (6): 528-534.doi: 10.16288/j.yczz.14-440

• Reviews • Previous Articles     Next Articles

The transcriptome research progresses of skin hair follicle development

Wei Jiang, Yixing Fan, Xian Qiao, Yanjun Zhang, Zhihong Liu, Yanhong Zhao, Ruijun Wang, Zhixin Wang, Wenguang Zhang, Rui Su, Jinquan Li   

  1. Inner Mongolia Key Laboratory of Animal Genetics, Breeding and Reproduction, Inner Mongolia Agricultural University, Hohhot 010018, China
  • Received:2014-12-12 Revised:2015-04-15 Online:2015-06-20 Published:2015-05-07

Abstract: Recently, transcriptome sequencing technology has achieved significant progresses in gene network regulation of important economic traits in animals. As the derivative of mammalian skin, hair follicle is capable of self-renew. Its proliferation and differentiation result in hair formation. Researches have revealed that many growth factors and receptors coordinate genes and environment, as well as play an extremely important role during hair growth. In this review, we summarize the progresses that transcriptome sequencing technologies have achieved in researches of hair follicle development and renegeration in a variety of species, such as humans, mice, goats. We aim to provide theoretical mechanisms for the artificial interference of villus growth cycle, and new ideas for therapeutic treatment of skin hair follicle- related diseases.

Key words: hair follicle, transcriptome, human, mice, goat