遗传学视角下东亚人群的起源和演化

doi:10.16288/j.yczz.18-202

遗传 ›› 2018, Vol. 40 ›› Issue (10): 814-824.doi: 10.16288/j.yczz.18-202

遗传学视角下东亚人群的起源和演化

田娇阳(),李玉春,孔庆鹏(),张亚平

中国科学院昆明动物研究所,遗传资源与进化国家重点实验室,昆明 650223

收稿日期:2018-07-16 修回日期:2018-09-25 出版日期:2018-10-20 发布日期:2018-09-26
作者简介:田娇阳,博士,助理研究员,研究方向：东亚人群源流历史。E-mail: tianjiaoyang@yeah.net
基金资助:
国家自然科学基金项目(31601017);云南省应用基础研究计划项目(2017FB044);中国科学院“西部之光”人才培养引进计划项目和国家重点研发计划项目(2016YFC1201704)

The origin and evolution history of East Asian populations from genetic perspectives

Jiaoyang Tian(), Yuchun Li, Qingpeng Kong(), Yaping Zhang

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China

Received:2018-07-16 Revised:2018-09-25 Published:2018-10-20 Online:2018-09-26
Supported by:
[the National Natural Science Foundation of China(31601017);Yunnan Applied Basic Research Project(2017FB044);CAS “Light of West China” Program and National Key Research and Development Program of China(2016YFC1201704)

摘要/Abstract

摘要：

东亚是研究解剖学意义上现代人迁徙和演化的重要地带之一,该地区现代人群的起源及形成问题一直都是人类学领域广泛关注的焦点。遗传学研究为重建东亚人群历史提供了新的视角和见解。越来越多的遗传学证据表明,现代人约20万年前起源于非洲的晚期智人,并于10万年前走出非洲,大约在5~6万年前沿海岸线快速到达东亚南部,进而扩散到整个东亚地区。早期智人可能对走出非洲的现代人有一定程度的遗传贡献。早期定居、文化同化、人群迁徙以及基因交流等,对东亚人群的起源和演化起着至关重要的作用。前期的研究对东亚人群的源流历史进行了细致的分析,很大程度上解决了考古学、历史学等领域长期以来存在的分歧,然而这还需通过全基因组学和古DNA研究的进一步验证。本文从遗传学视角梳理和总结了东亚人群起源、迁徙和演化的历史,完善了对东亚人群演变的系统认识,并对未来东亚人群源流历史研究的发展方向做了展望。

关键词: mtDNA, Y染色体, 全基因组, 古DNA, 东亚人群

Abstract:

East Asia is widely concerned as one of the important places for the dispersal and evolution of the Anatomically Modern Human (AMH). How the diverse ethnic groups in East Asia originated and diversified is also widely focused by different disciplines of Anthropology. The adoption of genetic data had provided new clues for reconstructing the genetic history of East Asian populations. Genetic studies supported the hypothesis that the AMHs originated from Africa’s Homo sapiens at about 200 kilo years ago (kya) and then migrated out of Africa at ~100 kya, followed by expansions into the whole East Asia since their arrival in Southern East Asia at 5~6 kya along the coastal route. Early Homo Sapiens might have genetic contribution to the non-African AMHs. Early settlement, cultural assimilation, population migration and genetic exchanges are crucial in the origination and evolution of East Asia populations. Previous studies made detailed analysis for the genetic history of East Asian populations, which largely resolved the longstanding divergence between archaeology and history. However, this needs further verification by whole-genome sequencing and ancient DNA studies. Here we briefly reviewed the progresses of genetic studies in exploring the population origin, dispersal and diversification in East Asia, which improved understanding of the evolution of East Asian populations. We also prospected the future of genetic studies in revealing the prehistory of East Asians.

Key words: mitochondrial DNA, Y chromosome, nuclear genome, ancient DNA, East Asians

田娇阳, 李玉春, 孔庆鹏, 张亚平. 遗传学视角下东亚人群的起源和演化[J]. 遗传, 2018, 40(10): 814-824.

Jiaoyang Tian, Yuchun Li, Qingpeng Kong, Yaping Zhang. The origin and evolution history of East Asian populations from genetic perspectives[J]. Hereditas(Beijing), 2018, 40(10): 814-824.

参考文献

[1]	Cann RL, Stoneking M, Wilson AC . Mitochondrial DNA and human evolution. Nature, 1987,325(6099):31-36.
[2]	Yao YG, Lü XM, Luo HR, Li WH, Zhang YP . Gene admixture in the silk road region of China: evidence from mtDNA and melanocortin 1 receptor polymorphism. Genes Genet Syst, 2000,75(4):173-178.
[3]	Yao YG, Kong QP, Bandelt HJ, Kivisild T, Zhang YP . Phylogeographic differentiation of mitochondrial DNA in Han Chinese. Am J Hum Genet, 2002,70(3):635-651.
[4]	Kong Q, Yao Y, Sun C, Bandelt H, Zhu C, Zhang Y . Phylogeny of east asian mitochondrial DNA lineages inferred from complete sequences. Am J Hum Genet, 2003,73(3):671-676.
[5]	Kong QP, Bandelt H-J, Sun C, Yao YG, Salas A, Achilli A, Wang C-Y, Zhong L, Zhu CL, Wu SF . Updating the east asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations. Hum Mol Genet, 2006,15(13):2076-2086.
[6]	Kong QP, Salas A, Sun C, Fuku N, Tanaka M, Zhong L, Wang CY, Yao YG, Bandelt HJ . Distilling artificial recombinants from large sets of complete mtDNA genomes. PLoS One, 2008,3(8):e3016.
[7]	Su B, Xiao J, Underhill P, Deka R, Zhang W, Akey J, Huang W, Shen D, Lu D, Luo J, Chu J, Tan J, Shen P, Davis R, Cavalli-Sforza L, Chakraborty R, Xiong M, Du R, Oefner P, Chen Z, Jin L . Y-Chromosome evidence for a northward migration of modern humans into eastern asia during the Last Ice Age. Am J Hum Genet, 1999,65(6):1718-1724.
[8]	Jin L, Su B . Natives or immigrants: modern human origin in East Asia. Nat Rev Genet, 1(2):126-133.
[9]	Ke Y, Su B, Song X, Lu D, Chen L, Li H, Qi C, Marzuki S, Deka R, Underhill P . African origin of modern humans in east asia: a tale of 12,000 Y chromosomes. Science, 2000,292(5519):1151-1153.
[10]	Yan S, Wang CC, Zheng HX, Wang W, Qin ZD, Wei LH, Wang Y, Pan XD, Fu WQ, He YG . Y chromosomes of 40% chinese descend from three neolithic super-grandfathers. PLoS One, 2004,9(8):e105691.
[11]	Kong QP, Sun C, Wang HW, Zhao M, Wang WZ, Zhong L, Hao XD, Pan H, Wang S-Y, Cheng YT . Large-scale mtDNA screening reveals a surprising matrilineal complexity in East Asia and its implications to the peopling of the region. Mol Biol Evol, 2001,28(1):513-522.
[12]	Peng MS, He JD, Fan L, Liu J, Adeola AC, Wu SF, Murphy RW, Yao YG, Zhang YP . Retrieving Y chromosomal haplogroup trees using GWAS data. Eur J Hum Genet, 2004,22(8):1046-1050.
[13]	Van OM, Van GA, Kayser M, Decorte R, Larmuseau MH . Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome. Hum Mutat, 2014,35(2):187-191.
[14]	Li H, Durbin R . Inference of human population history from individual whole-genome sequences. N

编辑推荐

Metrics

www.chinagene.cn
备案号：京ICP备09063187号-4
总访问:,今日访问:,当前在线:

遗传学视角下东亚人群的起源和演化

The origin and evolution history of East Asian populations from genetic perspectives

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics