遗传 ›› 2017, Vol. 39 ›› Issue (10): 908-917.doi: 10.16288/j.yczz.17-079

• 综述 • 上一篇    下一篇

PEX基因在过氧化物酶体形成及真菌致病性中的作用

高飞雁1,2(),李玲2,3,王教瑜2(),王艳丽2,孙国昌2()   

  1. 1. 浙江师范大学化学与生命科学学院,金华 321004
    2. 浙江省农业科学院植物保护与微生物研究所,省部共建国家重点实验室培育基地浙江省植物有害生物防控重点实验室,杭州 310021
    3. 浙江农林大学农业与食品科学学院,临安 311300
  • 收稿日期:2017-03-06 修回日期:2017-04-11 出版日期:2017-10-20 发布日期:2017-06-19
  • 作者简介:高飞雁,硕士研究生,专业方向:生物化学。E-mail: 1353423503@qq.com|王教瑜,博士,副研究员,研究方向:真菌功能基因组学。E-mail: wangjiaoyu78@sina.com|孙国昌,博士,研究员,研究方向:植物病原真菌学。E-mail: sungc01@sina.com
  • 基金资助:
    国家自然科学基金(31470249);中国博士后基金(2016M592018)

The functions of PEX genes in peroxisome biogenesis and pathogenicity in phytopathogenic fungi

Gao Feiyan1,2(),Li Ling2,3,Wang Jiaoyu2(),Wang Yanli2,Sun Guochang2()   

  1. 1. School of Chemistry and Life Science Zhejiang Normal University, Jinhua 321004, China
    2. State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Plant Protection Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China
    3. School of Agricultural and Food Sciences, Zhejiang Agriculture and Forest University, Lin’an 311300, China;
  • Received:2017-03-06 Revised:2017-04-11 Online:2017-10-20 Published:2017-06-19
  • Supported by:
    the Natural Science Foundation of China(31470249);the China Postdoctoral Science Foundation(2016M592018)

摘要:

过氧化物酶体(peroxisomes)是一类真核生物中普遍存在的细胞器,参与β-氧化、乙醛酸循环等多种重要的生化代谢。研究表明,过氧化物酶体在植物病原真菌侵染寄主过程中具有着举足轻重的作用。参与过氧化物酶体形成与增殖的基因,通常称为PEX基因。近年来,越来越多的PEX基因在植物病原真菌中得到鉴定,真菌过氧化物酶体的形成机制及其在植物病原真菌生长发育和致病过程中的作用越来越受到研究者的关注。本文围绕PEX 基因在过氧化物酶体形成中的作用、对过氧化物酶体相关生化代谢的影响,以及与植物病原真菌生长发育和致病性的关系进行了综述,以期为植物病原真菌致病机理研究和病害防控提供借鉴和参考。

关键词: 过氧化物酶体, PEX基因, 植物病原真菌, 致病性

Abstract:

Peroxisomes are cellular organelles present ubiquitously in eukaryotic cells and are involved in β-oxidation, glyoxylate cycle and a variety of biochemical metabolisms. Recently peroxisomes have been demonstrated to play vital roles in the host infection processes by plant fungal pathogens. The biogenesis of peroxisomes requires a category of proteins named peroxins, which are encoded by the PEX genes. So far, more than 10 PEX genes were isolated in phytopathogenic fungi, and significant research efforts are focused on the mechanism of peroxisome formation and the roles of peroxisome in the development and pathogenicity of fungal pathogens. In this review, we summarize the latest advances in peroxisome biogenesis and functions in pathogenic fungi, including the roles of PEXs in life cycle of peroxisome, peroxisome related metabolisms, and fungal development, infection and pathogenicity, in order to provide references for future studies in plant pathogenic fungi and the control of disease.

Key words: peroxisomes, PEX genes, phytopathogenic fungi, pathogenicity