遗传 ›› 2011, Vol. 33 ›› Issue (2): 109-116.doi: 10.3724/SP.J.1005.2011.00109
何彩云, 袁媛
收稿日期:2010-05-15
修回日期:2010-07-26
出版日期:2011-02-20
发布日期:2011-02-25
通讯作者:
袁媛
E-mail:yyuan@mail.cmu.edu.cn
基金资助:国家重点基础研究发展规划(973计划)项目(编号：2010CB529304)和辽宁省高校重点实验室项目(编号：LS2010167)资助
HE Cai-Yun, YUAN Yuan
Received:2010-05-15
Revised:2010-07-26
Online:2011-02-20
Published:2011-02-25
Contact:
YUAN Yuan
E-mail:yyuan@mail.cmu.edu.cn
摘要： 幽门螺杆菌相关胃癌是一种由遗传、环境、生活方式等因素共同作用所致的特殊类型胃癌。它的发病过程至少包括炎症、萎缩和癌变3个主要阶段。宿主基因单核苷酸多态性(SNP)包括炎症反应、胃酸抑制、免疫识别等相关基因SNP, 可能特异性参与了幽门螺杆菌相关胃癌发生发展过程中的不同阶段。文章综述与幽门螺杆菌相关胃癌发病3个主要病理阶段相关的宿主基因SNP及其与胃癌发病风险关系的研究进展。
何彩云，袁媛. 宿主基因单核苷酸多态性与幽门螺杆菌相关胃癌[J]. 遗传, 2011, 33(2): 109-116.
HE Cai-Yun, YUAN Yuan. Single nucleotide polymorphisms and helicobacter pylori-related gastric cancer[J]. HEREDITAS, 2011, 33(2): 109-116.
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