遗传 ›› 2002, Vol. 24 ›› Issue (2): 223-226.
• 论文 • 上一篇
蒋思文;彭健;熊远著 JINAG Si-wen;PENG Jian;XIONG Yuan-zhu
摘要: 黑素皮质素受体是G-蛋白耦联受体超家族成员。5个黑素皮质素受体基因已经被克隆和鉴定,并有不同的组织分布和生物学功能。本文综述了黑素皮质素受体3和受体4基因调控采食量和能量稳态的研究进展。
Abstract:The melanocortin receptors are members of the super-family of G-protein coupled receptors.To date,five melanocortin receptor genes (MC1R-MC5R) have been cloned and characterized.These receptorsdiffer in their tissue distributions and physiological roles.This review focuses on the roles of MC3R and MC4R in regulation of food intake and energy homeostasis.