骨形成蛋白15基因的研究进展

遗传 ›› 2003, Vol. 25 ›› Issue (6): 725-728.

骨形成蛋白15基因的研究进展

侯振平;蒋思文 HOU Zheng-Ping;JIANG Si-Wen

华中农业大学农业部猪遗传育种重点开放实验室，武汉 430070 Agricultural Ministry Key Laboratory of Pig Genetics and Breeding,Huazhong Agricultural University,Wuhan 430070,China

收稿日期:1900-01-01 出版日期:2003-12-10 发布日期:2003-12-10

Advance in Bone Morphogenetic Protein-15 Gene

Received:1900-01-01 Online:2003-12-10 Published:2003-12-10

摘要/Abstract

摘要： 骨形成蛋白是属于转移生长因子-β超家族生长因子的一种分泌型信号分子。迄今为止，已有30多个骨形成蛋白被确定，骨形成蛋白15基因在卵母细胞中表达，具有推动卵泡生长，阻止黄体早熟的作用。本文综述了骨形成蛋白15基因的研究现状。
Abstract:Bone morphogenetic proteins (BMPs) are secreted signalling molecules belonging to the transforming growth factor-β (TGF-β) surperfamily.Up to date,more than 30 members of BMPs are identified.Bone morphogenetic protein-15 is only expressed in oocytes.Oocyte-specific BMP-15 might promote follicle growth in vivo,while preventing premature luteinization.This paper biefly discusses the progress in the research area of BMP-15 gene being as a candidate gene for litter size.

关键词: 骨形成蛋白, 转移生长因子-β, bone morphogenetic proteins, transforming growth factor-β, 骨形成蛋白15基因
Key words

侯振平，蒋思文. 骨形成蛋白15基因的研究进展[J]. 遗传, 2003, 25(6): 725-728.

HOU Zheng-Ping, JIANG Si-Wen. Advance in Bone Morphogenetic Protein-15 Gene[J]. HEREDITAS, 2003, 25(6): 725-728.

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