遗传 ›› 2006, Vol. 28 ›› Issue (8): 927-932.

• 研究报告 • 上一篇    下一篇

不同生长时期基因调控对南阳牛生长发育的影响

高 雪 1 ,徐秀容2 ,任红艳1 ,张英汉2 ,许尚忠1   

  1. 1. 中国农业科学院畜牧研究所 北京 100094;2. 西北农林科技大学动物科技学院 杨凌 712100

  • 收稿日期:2005-07-28 修回日期:2005-10-22 出版日期:2006-08-10 发布日期:2006-08-10
  • 通讯作者: 高雪

The modulation and control on growth and development traits of Nanyang Cattle in different phase

  1. 1.The Institute of Animal Science, Chinese Academic Agriculture Science, Beijing 100094,China;
    2.Northwest Sci-tech University of Agriculture and Forestry, Yangling 712100,China

  • Received:2005-07-28 Revised:2005-10-22 Online:2006-08-10 Published:2006-08-10

摘要: 以南阳牛为试验动物,利用PCR-SSCP和PCR-RFLP技术研究了南阳牛生长激素(GH)基因,IGF-I基因以及IGF-IBP3基因的遗传多态,并分析了遗传多态位点对南阳牛0月龄、6月龄、12月龄、18月龄、24月龄以及36月龄不同生长时期生长发育性状的影响。结果表明: 在6月龄~18月龄,GH基因的GH-P5位点的BB基因型对南阳牛的体长、体高显著的正效应;在生长的后期(24月龄~36月龄),IGF-IBP3-P5基因位点对南阳牛的后躯发育起主要调控作用,BB基因型个体的尻宽显著高于AA型。这表明基因的正效应不是在所有的生长周期表现,而是在特定的时期表现对南阳牛生长发育的显著影响。

关键词: 不同生长期, 南阳牛, 生长性状, GH和IGF-I基因

Abstract: This study was conducted to identify polymorphisms of the Nangyang cattle’s growth hormone (GH) and insulin-like growth factor-I (IGF-I) and insulin-like growth factor-I binding protein 3 gene by the single nucleotide Polymorphisms and Polymerase chain reaction-based restriction fragment length polymorphism and to study association of polymorphisms identified in these genes with growth traits of the birth, 6 month, 12 month, 18 month, 24 month and 36 month. Results from the analysis showed a significant association of the BB genotype in the promoter of GH gene (GH-P5) with higher body length and body height during from 6month to 18month. From 24month to 36 month, the IGF-I-BP3 locus has a dominance modulation and control effect on backbody in Nanyang Cattle, and the BB genotype with higher Rump width than AA.

中图分类号: