贵州苗族新生儿HbF中Gγ/Aγ比值测定与AγT基因频率分析

遗传 ›› 1993, Vol. 15 ›› Issue (3): 1-3.

• 论文 • 下一篇

贵州苗族新生儿HbF中Gγ/Aγ比值测定与AγT基因频率分析

易志勤1;南国华1;陈松林2;梁植权2;姚源黎3;杨文鸿3;王立荣3;丁桂华3 YI Zhi-Qin1;NAN Guo-Hua1;CHEN Song-Sen2;LIANG Zhi-Quan2;YAO Yuan-Li3;YANG Wen-Hong3;WANG Li-Rong3;DING Gui-Hua3

1.江西省赣南医学院生物化学教研室，赣州 341000；江西医学院生物化学教研室，南昌330006 1.Department of Biochemistry,Jiangxi Gannan Medical College,Ganzhou 341000;Department of Biochemistry,Jiangxi Medical College,Nanchang 330006 2.中国医学科学院基础医学研究所，北京 100005 2.Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Beijing 100005 3.贵州省凯里市妇幼保健院，凯里 556000 3.The Women and Children’s Health Hospital of Kaili City in Guizhou Province,556000

收稿日期:1900-01-01 出版日期:1993-06-10 发布日期:1993-06-10

Ratios of Gγ and Aγ Chains,and AγT Gene Frequency in Miao Nationality Newbornsi in Guizhou Province

Received:1900-01-01 Online:1993-06-10 Published:1993-06-10

摘要/Abstract

摘要： 用含Triton X-100的酸性尿素聚丙烯酰胺凝胶电泳(PAGE)法测定了贵州省108例苗族新生儿脐带血胎儿血红蛋白(HbF)中Gγ/Aγ值.显示107例(占99.07%)新生儿的Gγ值在55-78%之间,均值与标准差为70.42±3.45;高Gγ值者1例(占0.925%);低Gγ值者未发现。用Large-pore Vydac C4柱反相高效液相层析法对108例样本进行了AγT基因频率（fAγT）分析，fAγT为0.0648。
The ratio of Gγ to Aγ of fetal hemoglobin inn 108 cord blood samples of Miao nationality newborns in Guizhou province was determined by the polyacrylamide gel electrophoresis(PAGE).The result showed that one case had high Gγ value(0.925%) and 107 babies the normal Gγ values of 55 to 78%(70.42+3.45)。The AγT gene frequency(fAγT) analysis in 108 samples was done by high pressure liquid chromatography using a large pore Vydac C4 column,the fAγT was 0.0648.

关键词: AγT基因频率, 苗族
Key words, Fetal hemoglobin, Gγ/Aγ值, 血红蛋白F

易志勤，南国华，陈松林，梁植权，姚源黎，杨文鸿，王立荣，丁桂华. 贵州苗族新生儿HbF中Gγ/Aγ比值测定与AγT基因频率分析[J]. 遗传, 1993, 15(3): 1-3.

YI Zhi-Qin, NAN Guo-Hua, CHEN Song-Sen, LIANG Zhi-Quan, YAO Yuan-Li, YANG Wen-Hong, WANG Li-Rong, DING Gui-Hua. Ratios of Gγ and Aγ Chains,and AγT Gene Frequency in Miao Nationality Newbornsi in Guizhou Province[J]. HEREDITAS, 1993, 15(3): 1-3.

贵州苗族新生儿HbF中Gγ/Aγ比值测定与AγT基因频率分析

Ratios of Gγ and Aγ Chains,and AγT Gene Frequency in Miao Nationality Newbornsi in Guizhou Province

PDF (PC)

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics