遗传 ›› 2014, Vol. 36 ›› Issue (12): 1219-1225.doi: 10.3724/SP.J.1005.2014.1219

• 综述 • 上一篇    下一篇

植物NBS类抗病基因的进化

罗莎   

  1. 江西农业大学农学院园艺系, 南昌 330045
  • 收稿日期:2014-06-19 出版日期:2014-12-20 发布日期:2014-12-20
  • 作者简介:罗莎, 博士, 讲师, 研究方向:植物抗病基因进化。
  • 基金资助:

    国家自然科学基金项目(编号:31360050)资助

Evolution of plant NBS encoding disease resistance genes

Luo Sha   

  1. Department of Horticulture, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China
  • Received:2014-06-19 Online:2014-12-20 Published:2014-12-20

摘要:

NBS(Nucleotide-binding site)类抗病基因是植物中最重要的一类抗病基因, 其进化模式、结构特点和功能调控一直是抗病基因研究领域的热点。这类基因具有保守的结构域, 广泛存在于植物基因组中, 在不同植物基因组中数目差异较大且具有较低的表达量。此外, 同源NBS类抗病基因之间通过频繁的序列交换产生广泛的序列多样性, 且抗病基因位点具有较差的线性。依据基因之间序列交换的频率, 抗病基因可分为TypeⅠ和TypeⅡ两类。文章从抗病基因的结构、数量、分布、序列多样性、进化模式以及表达调控等方面进行了综述, 旨在为后续NBS类抗病基因的相关研究提供参考。

关键词: NBS类抗病基因, 进化模式, 序列多样性, 线性关系

Abstract:

NBS (nucleotide-binding site) genes are a major class of disease resistance (R) genes in plants. Studies on their evolutionary pattern, structure characteristics and functional regulation have been always paid much attentions. NBS genes exist in a various plants by different copy numbers and low expression levels. They encode pro-teins containing conserved NBS domain and C-terminal leucine-rich repeats (LRRs). The NBS genes have frequent sequence exchanges among homologs and consequently show extensive diversity and poor synteny. Two types of NBS genes are distinguished based on their frequency of sequence exchanges. In this review, we summarize the latest progress of plant NBS encoding genes in terms of structure, number, evolutionary pattern, sequence diversity and distribution in genome, providing some insights into the further research on NBS genes in plant.

Key words: NBS encoding gene, evolutionary pattern, sequence diversity, synteny