[1] |
Chen LG, Chen XW, Huang X, Song BL, Wang Y, Wang YG . Regulation of glucose and lipid metabolism in health and disease. Sci China Life Sci, 2019,62(11):1420-1458.
doi: 10.1007/s11427-019-1563-3
pmid: 31686320
|
[2] |
Luo J, Yang HY, Song BL . Mechanisms and regulation of cholesterol homeostasis. Nat Rev Mol Cell Biol, 2020,21(4):225-245.
doi: 10.1038/s41580-019-0190-7
pmid: 31848472
|
[3] |
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao XL, Luo J, Qi W, Song BL . Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis. Nature, 2020, doi: 10.1038/s41586-020-2928-y.
pmid: 33208969
|
[4] |
Song BL, Sever N, DeBose-Boyd RA. Gp78, a membrane- anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase. Mol Cell, 2005,19(6):829-840.
pmid: 16168377
|
[5] |
Altmann SW, Davis Jr HR, Zhu LL, Yao XR, Hoos LM, Tetzloff G, Iyer SPN, Maguire M, Golovko A, Zeng M, Wang LQ, Murgolo N, Graziano MP . Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science, 2004,303(5661):1201-1204.
pmid: 14976318
|
[6] |
Zhang YY, Fu ZY, Wei J, Qi W, Baituola G, Luo J, Meng YJ, Guo SY, Yin HY, Jiang SY, Li YF, Miao HH, Liu Y, Wang Y, Li BL, Ma YT, Song BL . A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption. Science, 2018,360(6393):1087-1092.
pmid: 29880681
|
[7] |
Garcia CK, Wilund K, Arca M, Zuliani G, Fellin R, Maioli M, Calandra S, Bertolini S, Cossu F, Grishin N, Barnes R, Cohen JC, Hobbs HH . Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. Science, 2001,292(5520):1394-1398.
doi: 10.1126/science.1060458
pmid: 11326085
|
[8] |
Abifadel M, Varret M, Rabès JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, Derré A, Villéger L, Farnier M, Beucler I, Bruckert E, Chambaz J, Chanu B, Lecerf JM, Luc G, Moulin P, Weissenbach J, Prat A, Krempf M, Junien C, Seidah NG, Boileau C . Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet, 2003,34(2):154-156.
pmid: 12730697
|
[9] |
Brown MS, Goldstein JL . A receptor-mediated pathway for cholesterol homeostasis. Science, 1986,232(4746):34-47.
pmid: 3513311
|
[10] |
Yu HJ, Rimbert A, Palmer AE, Toyohara T, Xia YL, Xia F, Ferreira LMR, Chen ZF, Chen T, Loaiza N, Horwitz NB, Kacergis MC, Zhao LP, Consortium B, Soukas AA, Kuivenhoven JA, Kathiresan S, Cowan CA. GPR146 deficiency protects against hypercholesterolemia and atherosclerosis. Cell, 2019, 179(6): 1276-1288.e1214.
|
[11] |
Han FF, Liu X, Chen CF, Liu YN, Du MK, Zhou Y, Liu Y, Song BL, He HH, Wang Y . Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice. Cell Res, 2020,30(4):363-365.
pmid: 32203133
|
[12] |
Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH . Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science, 2000,290(5497):1771-1775.
pmid: 11099417
|
[13] |
Ge L, Wang J, Qi W, Miao HH, Cao J, Qu YX, Li BL, Song BL . The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. Cell Metab, 2008,7(6):508-519.
pmid: 18522832
|
[14] |
Robinson JG, Farnier M, Krempf M, Bergeron J, Luc G, Averna M, Stroes ES, Langslet G, Raal FJ, Shahawy ME, Koren MJ, Lepor NE, Lorenzato C, Pordy R, Chaudhari U, Kastelein JJP . Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. N Engl J Med, 2015,372(16):1489-1499.
|
[15] |
Sabatine MS, Giugliano RP, Wiviott SD, Raal FJ, Blom DJ, Robinson J, Ballantyne CM, Somaratne R, Legg J, Wasserman SM, Scott R, Koren MJ, Stein EA . Efficacy and safety of evolocumab in reducing lipids and cardiovascular events. N Engl J Med, 2015,372(16):1500-1509.
|
[16] |
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the scandinavian simvastatin survival study(4S). in 4444 patients with coronary heart disease: the scandinavian simvastatin survival study (4S). Lancet, 1994,344(8934):1383-1389.
|