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Hereditas(Beijing) ›› 2017, Vol. 39 ›› Issue (11): 1033-1045.doi: 10.16288/j.yczz.17-286

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Application of genomic selection in farm animal breeding

Cheng Tan1,2,3(),Cheng Bian1,Da Yang4,Ning Li1,Zhenfang Wu2,3(),Xiaoxiang Hu1()   

  1. 1. State Key Laboratory of Agricultural Biotechnology, China Agricultural University, Beijing 100193, China
    2. National Engineering Research Center for Breeding Swine Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China
    3. Guangdong Wens Foodstuff Group Co., Ltd., Yunfu 527400, China
    4. Department of Animal Science, University of Minnesota, Saint Paul MN 55108, USA
  • Received:2017-08-29 Revised:2017-10-20 Online:2017-11-20 Published:2017-12-20
  • Supported by:
    the 948 Program of the Ministry of Agriculture of China(2012-G1(4));the National High-Tech Research and Development Program of China (863 Program)(2011AA100301)

Abstract:

Genomic selection (GS) has become a widely accepted method in animal breeding to genetically improve economic traits. With the declining costs of high-density SNP chips and next-generation sequencing, GS has been applied in dairy cattle, swine, poultry and other animals and gained varying degrees of success. Currently, major challenges in GS studies include further reducing the cost of genome-wide SNP genotyping and improving the predictive accuracy of genomic estimated breeding value (GEBV). In this review, we summarize various methods for genome-wide SNP genotyping and GEBV prediction, and give a brief introduction of GS in livestock and poultry breeding. This review will provide a reference for further implementation of GS in farm animal breeding.

Key words: genome selection, animal breeding, genotyping, next-generation sequencing