羊慢病毒及其抗性基因研究进展

doi:10.3724/SP.J.1005.2014.1204

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HEREDITAS(Beijing) ›› 2014, Vol. 36 ›› Issue (12): 1204-1210.doi: 10.3724/SP.J.1005.2014.1204

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Progress on ovine lentivirus and its resistant genes

Feng Guan¹, Guoqing Shi², Jin Zhao¹, Yimin Wang³

1. College of Life Sciences, China Jiliang University, Hangzhou 310018, China;
2. The Key Sheep Breeding and Reproduction Biotechnology Laboratory of Xinjiang Production and Construction Group, Shihezi 832000, China;
3. Hangzhou Caiyang Animal Husbandry Co., Ltd. Hangzhou 310000, China

Received:2014-05-09 Online:2014-12-20 Published:2014-12-20

Abstract

Abstract: Ovine lentivirus, also termed as small ruminant lentiviruses (SRLVs), includesmaedi-visna virus (MVV) and caprine arthritis encephalitis virus (CAEV), which can infect sheep and goats. SRLVs are wide spread throughout the world causing serious economic implications for animal industry. Breed differences in susceptibility to MVV had suggested a strong genetic diversity in sheep. Genome wide association study (GWAS) indicated that a SNP (E35K) in ovine transmemebrane protein 154 (TMEM154) gene was significantly associated with sheep resistance to MVV and can be used as a molecular marker in sheep resistant selection breeding. Here, we review the progress of E35K mutation in sheep TMEM154 gene and its effects on resistance to MVV, and other lentivirusresistant genes including zinc finger cluster, chemokine reveptor 5 (CCR5), tripartite motif-containing 5 alpha (TRIM5α), apolipoprotein B mRNA-editing catalytic polypetide like 3 (APOBEC3), developmental pluripotencyassociated 2 (DPPA2) and DPPA4. Furthermore, SRLVs and the epidemic status are introduced. We hope to provide some guidance for sheep re-sistant breeding.

Key words: ovine lentivirus, maedi-visna virus, TMEM154 gene, mutation, resistance

Feng Guan, Guoqing Shi, Jin Zhao, Yimin Wang. Progress on ovine lentivirus and its resistant genes[J]. HEREDITAS(Beijing), 2014, 36(12): 1204-1210.

References

[1] Ramírez H, Reina R, Amorena B, de Andrés D, Martínez HA. Small ruminant lentiviruses: genetic variability, tropism and diagnosis. Viruses, 2013, 5(4): 1175–1207.
[2] Larruskain A, Jugo BM. Retroviral infections in sheep and goats: small ruminant lentiviruses and host interaction. Viruses, 2013, 5(8): 2043–2061.
[3] 曲娟娟, 刘慧敏, 相文华, 沈荣显. 山羊关节炎–脑炎的研究现状. 中国预防兽医学报, 2005, 27(4): 431–434.
[4] Blacklaws BA. Small ruminant lentiviruses: immuno-pathogenesis of visna-maedi and caprine arthritis and en-cephalitis virus. Comp Immunol Microbiol Infect Dis, 2012, 35(3): 259–269.
[5] Shah C, Huder JB, B?ni J, Sch?nmann M, Mühlherr J, Lutz H, Schüpbach J. Direct evidence for natural transmission of small-ruminant lentiviruses of subtype A4 from goats to sheep and vice versa. J Virol, 2004, 78(14): 7518–7522.
[6] Minardi da Cruz JC, Singh DK, Lamara A, Chebloune Y. Small ruminant lentiviruses (SRLVs) break the species barrier to acquire new host range. Viruses, 2013, 5(7): 1867–1884.
[7] Smith JB, Jenks JA, Grovenburg TW, Klaver RW. Disease and Predation: Sorting out Causes of a Bighorn Sheep (Ovis canadensis) Decline. PLoS ONE, 2014, 9(2): e88271.
[8] White SN, Knowles DP. Expanding possibilities for inter-vention against small ruminant lentiviruses through genetic marker-assisted selective breeding. Viruses, 2013, 5(6): 1466–1499.
[9] Leymaster KA, Chitko-McKown CG, Clawson ML, Harhay GP, Heaton MP. Effects of TMEM154 haplotypes 1 and 3 on susceptibility to ovine progressive pneumonia virus following natural exposure in sheep. J Anim Sci, 2013, 91(11): 5114–5121.
[10] Leroux C, Cruz JC, Mornex JF. SRLVs: a genetic continuum of lentiviral species in sheep and goats with cumulative evidence of cross species transmission. Curr HIV Res, 2010, 8(1): 94–100.
[11] White SN, Mousel MR, Reynolds JO, Herrmann-Hoesing LM, Knowles DP. Deletion variant near ZNF389 is asso-ciated with control of ovine lentivirus in multiple sheep flocks. Anim Genet, 2014, 45(2): 297–300.
[12] Thormar H. The origin of lentivirus research: Maedi-visna virus. Curr HIV Res, 2013, 11(1): 2–9.
[13] Sider LH, Heaton MP, Chitko-McKown CG, Harhay GP, Smith TP, Leymaster KA, Laegreid WW, Clawson ML. Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes. Vet Res, 2013, 44: 64.
[14] Crawford TB, Adams DS, Cheevers WP, Cork LC. Chronic arthritis in goats caused by a retrovirus. Science, 1980, 207(4434): 997–999.
[15] Li Y, Zhou FJ, Li X, Wang JH, Zhao XP, Huang JH. De-velopment of TaqMan-based qPCR method for detection of caprine arthritis-encephalitis virus (CAEV) infection. Arch Virol, 2013, 158(10): 2135–2141.
[16] 夏炉明, 陈琦, 孙泉云. 梅迪–维斯纳病概述. 上海畜牧兽医通讯, 2011, (4): 56–57.
[17] Heaton MP, Clawson ML, Chitko-Mckown CG, Leymaster KA, Smith TPL, Harhay GP, White SN, Herrmann-Hoesing LM, Mousel MR, Lewis GS, Kalbfleisch TS, Keen JE, Laegreid WW. Reduced lentivirus susceptibility in sheep with TMEM154 mutations. PLoS Genet, 2012, 8(1): e1002467.
[18] Keen JE, Hungerford LL, Littledike ET, Wittum TE, Kwang J. Effect of ewe ovine lentivirus infection on ewe and lamb productivity. Prev Vet Med, 1997, 30(2): 155–169.
[19] White SN, Mousel MR, Herrmann-Hoesing LM, Reynolds JO, Leymaster KA, Neibergs HL, Lewis GS, Knowles DP. Genome-wide association identifies multiple genomic re-gions associated with susceptibility to and control of ovine lentivirus. PLoS ONE, 2012, 7(10): e47829.
[20] Benavides J, Fuertes M, García-Pariente C, Otaola J, Del-gado L, Giraldez J, García Marín JF, Carmen Ferreras M, Pérez V. Impact of maedi-visna in intensively managed dairy sheep. Vet J, 2013, 197(3): 607–612.
[21] Sigurdsson B, Grimsson H, Palsson PA. Maedi, a chronic, progressive infection of sheep's lungs. J Infect Dis, 1952, 90(3): 233–241.
[22] 邓普辉, 简子健, 刘君明, 阿合买提?买买提, 周自富, 朱飞兵. 绵羊进行性肺炎在世界的流行及控制. 新疆农业科学, 1992, (4): 189–192.
[23] Gudnadóttir M, Demosthe

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Progress on ovine lentivirus and its resistant genes

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