遗传 ›› 2014, Vol. 36 ›› Issue (12): 1269-1273.doi: 10.3724/SP.J.1005.2014.1269

• 遗传学教学 • 上一篇    下一篇

以CRISPR/Cas9专利为例的知识产权教育

樊祥宇1, 2, 廖国建3, 谢建平1   

  1. 1. 西南大学生命科学学院, 三峡库区生态环境与生物资源省部共建国家重点实验室培育基地, 三峡库区生态环境教育部重点实验室, 现代生物医药研究所, 重庆北碚 400715;
    2. 济南大学生物科学与技术学院, 济南 250022;
    3. 西南大学药学院, 现代生物医药研究所, 重庆北碚 400715
  • 收稿日期:2014-09-03 出版日期:2014-12-20 发布日期:2014-12-20
  • 通讯作者: 谢建平, 博士, 研究员, 研究方向:人类重要致病菌的致病耐药机理和新干预措施研发。Tel: 86-23-68367108; E-mail: georgex@swu.edu.cn E-mail:fxysnd@126.com
  • 作者简介:樊祥宇, 博士, 讲师, 研究方向:分枝杆菌噬菌体功能基因组学。
  • 基金资助:
    重庆市教委研究生教改项目“全球视野高层次人才培养的区域性跨院校支撑平台”(编号:YJG123104), 重庆市教委研究生优质课程《高级微生物学》, 西南大学本科生教改项目(编号:2013JY201), 教育部新世纪优秀人才资助计划(编号:NCET-11-0703), 国家自然科学基金(编号:81371851, 81071316, 81271882, 81301394)和中央高校基本科研业务费(编号:XDJK2011D006, XDJK2012D011, XDJK2012D007, XDJK2013D003, XDJK2014D040)资助。

Intellectual property education exemplified by the patents on the CRISPR/Cas9 system

Xiangyu Fan1, 2, Guojian Liao3, Jianping Xie1   

  1. 1. Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University, Beibei, Chongqing 400715, China;
    2. School of Biological science and technology, University of Jinan, Jinan 250022, China;
    3. Institute of Modern Biopharmaceuticals, School of Pharmaceutical Sciences, Southwest University, Beibei, Chongqing 400715, China
  • Received:2014-09-03 Online:2014-12-20 Published:2014-12-20

摘要: 随着世界经济全球化步伐的加快, 知识产权的重要性凸显。高校是知识产权意识和能力教育的主战场。我国现有知识产权教育与专业的密切程度急需提高。文章结合全球首个CRISPR/Cas9专利权的授权公布和作者授课经历, 提出了一种新的知识产权普及教育模式, 将知识产权教育分为启蒙教育和深入研修两个阶段。第一阶段将知识产权教育与专业课课程无缝整合, 后一阶段主要针对有志于发展成为知识产权专业人才的学生。我们认为这种教学模式的推广将解决现有知识产权教育中教材的欠缺以及教师的不足, 有利于知识产权意识在生物医学等理工科学生的普及。遗传学在生物医学中具有特别重要的地位, 因此, 文章以遗传学最近的热点技术之一——基于CRISPR/Cas的基因组编辑新工具为例进行阐述。CRISPR/Cas从最初的微生物遗传学发现到成为基因组编辑的重要工具, 贯穿了基础研究转化为关键技术的全过程, 可以很好体现生物医学相关的知识产权教育的精髓。

关键词: 知识产权教学, 生物医学教育, CRISPR/Cas系统

Abstract: With the accelerated globalization of the world economies, the role of intellectual property in the the competition is increasingly important. The universities are important base to instill the intellectual property awareness to the young generation. However, current model of intellectual property education cannot meet the needs of undergraduates. In this paper, we take the first patent issued for CRISPR/Cas9 system as a teaching example, and together with personal teaching experience in biomedicine related intellectual property, we propose a new way for intellectual property education which consists of two stages: enlightenment stage and in-depth training stage. In the former stage, we integrate the intellectual property education with the basic major courses. In the latter stage, students are encouraged to devote into intellectual property related career. This model can somehow solve the the current shortage of qualified teachers for biotechnology related intellectual property education and will facilitate the popularization of intellectual property in college students. Since genetics plays a pivotal role in biomedicine, this effort is illustrated by the novel genome editing technology based on the CRISPR/Cas9 system, which is one hotspot of recent studies. The trajectory of CRISPR/Cas9 from basic microbial genetics discovery to major tools for genome editing exeplified the essence of biomedicine related intellectual property education.

Key words: intellectual property, biomedical education, the CRISPR-Cas system