遗传 ›› 2001, Vol. 23 ›› Issue (2): 153-244.

• 论文 • 上一篇    下一篇

基于生物信息学的SNP候选位点搜寻方法

陈炜;张戈; 张思仲 CHEN Wei;ZHANG Ge;ZHANG Si-zhong   

  1. 华西医科大学附属第一医院医学遗传研究室,成都 610041 Department of Medical Genetics,The First Affiliated Hospital,West China University of Medical Sciences,Chengdu 610041, China
  • 收稿日期:1900-01-01 出版日期:2001-04-10 发布日期:2001-04-10

Discovery of Candidate SNP by Bioinformatic Methods

  • Received:1900-01-01 Online:2001-04-10 Published:2001-04-10

摘要: 单核苷酸多态性(Single Nucleotide Polymorphism,SNP)是人类基因组中最常见的遗传多态,在遗传学研究的很多方面具有重要的作用。它的搜寻正受到广泛关注。近年来,国际上出现了一种基于生物信息学的发掘SNP新方法。本文对该方法的两种策略及其各自所存在的问题作一介绍。
Abstract:Single Nucleotide Polymorphism (SNP), the most common form of human genetic variation, represents a valuable resources for a variety of genetic research. There is considerable interest in the discovery of it. Recently, a new method based on bioinfomatics has been developed for the discovery of SNP. In this paper, the two strategy of this method and their respective problem are discussed.

关键词: 生物信息学 Keywords, Single Nucleotide Polymorphism (SNP) bioinformatics, SNP), 单核苷酸多态性(Single Nucleotide Polymorphism