遗传 ›› 2002, Vol. 24 ›› Issue (5): 537-538.

• 论文 • 上一篇    下一篇

中国瑶族人群(广西)9个STR基因多态性研究

高放1;毕世华2;赖江华1;李生斌1;2   

  1. 1.西安交通大学部级法医学重点实验室,西安,710061; 2.中国科学院遗传与发育生物学研究所人类基因组中心,北京 100101
  • 收稿日期:1900-01-01 出版日期:2002-10-10 发布日期:2002-10-10

  • Received:1900-01-01 Online:2002-10-10 Published:2002-10-10

摘要: 采用STR基因扫描技术选择D3S1358,vWA,FGA,THO1,TPOX,CSF1P0,D5S818,
D13S317 和 D7S820 9种STR基因座,研究我国瑶族人群STR遗传多态性。在瑶族群体中9个STR基因座共检出61个等位基因,其频率分布在0.0054~0.5924,平均杂合度为0.7357,多态信息量为0.6887,累积个体识别率为2.02×10-10,非父排除率为0.9999。结果表明,在人类遗传学、法学科等领域建立本民族本地区遗传学资料是十分重要和必不可少的。

Study on 9 STR Loci Polymorphism from Chinese Yao Ethnic Group(Guangxi)
GAO Fang1,BI Shi-hua2,LAI Jiang-hua1,LI Sheng-bin1,2
1.National Laboratory of Forensic Sciences,Xian Jiaotong University,Xi'an 710061;
2.Human Genome Genter,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101 China
Abstract:Genetic polymorphism of nine STR loci was investigated from a Chinese Yao population based on STR Genescan.Sixty one alleles was determined for 9 loci,such as D3S1358,vWA,FGA,THO1,TPOX,CSF1P0,D5S818,D13S317 and D7S820 with their frequencies 0.0054~0.5924.The average heterozygosity(H) was 0.7357,polymorphism information content(PIC) was 0.6887,the accumulative discrimination power(DP) was 2.02×10-10 and the probability of paternity exclusion(PPE) was 0.9999.These results suggested that the nine STR loci are very useful for human identification,such as analyzing forensic casework,establishing DNA databases,processing paternity test and studying gene natural resources.
Key words:STR;genescan;Yao ethnic group;individual identification

关键词: STR, 基因扫描, 瑶族人群, 个体识别