遗传 ›› 2006, Vol. 28 ›› Issue (8): 1043-1050.

• 专论与综述 • 上一篇    下一篇

大豆过敏蛋白与品种改良

方旭前1,2,朱友林1,邱丽娟2,3   

  1. 1.南昌大学生命科学学院分子生物学与基因工程实验室,南昌330047;2. 中国农业科学院作物科学研究所,国家农作物基因资源与遗传改良重大科学工程,农业部作物种质资源与生物技术重点开放实验室,北京100081

  • 收稿日期:2005-07-30 修回日期:2006-04-04 出版日期:2006-08-10 发布日期:2006-08-10
  • 通讯作者: 邱丽娟

Soybean allergens and cultivar improvement

FANG Xu-Qian 1,2, ZHU You-Lin 1 , QIU Li-Juan 2

  

  1. 1. Laboratory of Molecular Biology and Gene Engineering, College of Life Science, Nanchang University, Nanchang 330047; 2. National Key Facility of Gene Resources and Genetic Improvement / Key Lab of Crop Germplasm Resources & Biotechnology , the Ministry of Agriculture , Institute of Crop Science , CAAS , Beijing 100081, China

  • Received:2005-07-30 Revised:2006-04-04 Online:2006-08-10 Published:2006-08-10
  • Contact: QIU Li-Juan

摘要: 食物过敏是一个全世界关注的公共卫生问题。大豆蛋白在食品加工业的广泛应用,对大豆敏感人群带来了潜在的威胁。如何降低大豆过敏原含量提升大豆食品安全已成为日益关注的问题。大豆种子过敏蛋白包括种子贮存蛋白、结构蛋白和防御相关蛋白,其中7S 伴球蛋白的多肽片段Gly m Bd 28K, Gly m Bd 30K和Gly m Bd 60K是三种主要的过敏原。目前通过对过敏蛋白的理化性质、过敏原性和基因结构的认识,运用食品加工工艺、传统育种及基因工程技术等方法,在减少大豆和大豆产品的过敏原性方面已取得一定的进展。本文拟从大豆过敏原的分类、主要过敏原Gly m Bd 28K和Gly m Bd 30K的理化性质及基因结构、大豆过敏蛋白在遗传改良中的应用对大豆过敏蛋白进行综述。

关键词: Gly m Bd 60K, Gly m Bd 30K, 大豆过敏原, Gly m Bd 28K

Abstract: Food hypersensitivity is a public sanitary problem drawing a worldwide attention. The increasing use of soybean (Glycine max) products in processed foods poses a potential threat to soybean-sensitive food-allergic individuals. How to decrease the content of allergens, and upgrade the food security has becoming an increasingly interested problem. Soybean allergens in seeds are compose of storage proteins, structure proteins, disease-related proteins. Among them the fragments of 7S Conglycinin Gly m Bd 28K, Gly m Bd 30K and Gly m Bd 60K are three major allergens. By recognizing allergens’ physicochemical property, hypersensitivity and gene structure, at present, it has got a certain progress to reduce the content of allergens in soybean and soybean product through food process, traditional breeding and gene engineering techniques. This paper will review the sort of soybean allergens, the physicochemical property of two Immunodominant Allergens Gly m Bd 28K Gly m Bd 30K and their gene structures respectively, and indicates attempts to develop hypoallergenic breeds.

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