中国北方汉族人群81个常染色体STR基因座多态性研究及突变调查

doi:10.16288/j.yczz.25-172

遗传 ›› 2026, Vol. 48 ›› Issue (5): 483-505.doi: 10.16288/j.yczz.25-172

中国北方汉族人群81个常染色体STR基因座多态性研究及突变调查

贺航¹(), 张金佩¹(), 张楚楚²(), 姜成涛³, 税薇薇¹, 郝世诚¹, 来宜雯¹, 缪磊¹, 王秋娟⁴, 郭小森⁴, 袁丽¹()

¹ 证据科学教育部重点实验室(中国政法大学)，司法文明协同创新中心，北京 100088
² 广东南天司法鉴定所，深圳 518045
³ 北京天平司法鉴定中心，北京 100025
⁴ 深圳华大法医科技有限公司，深圳 518083

收稿日期:2025-08-13 修回日期:2025-10-28 出版日期:2026-05-20 发布日期:2025-11-14
通讯作者: 袁丽，博士，教授，主任法医师，研究方向：法医物证学鉴定、教学和研究。E-mail: yuanliwcy@126.com
作者简介:贺航，硕士研究生，专业方向：法医物证学。E-mail: 806690390@qq.com;
张金佩，博士研究生，专业方向：法医物证学。E-mail: zhangjinpei1992@163.com;
张楚楚，硕士，主检法医师，研究方向：法医物证学。E-mail: zhchuch@mail3.sysu.edu.cn。
第一联系人：
贺航、张金佩和张楚楚并列第一作者。
基金资助:
中国政法大学科研创新项目(24KYGH017);中央高校基本科研业务费专项资金;广东省证据材料司法鉴定(南天)工程技术研究中心开放课题基金(ETRC202401)

Genetic polymorphism and mutation analysis of 81 autosomal STR loci in the Northern Han Chinese population

Hang He¹(), Jinpei Zhang¹(), Chuchu Zhang²(), Chengtao Jiang³, Weiwei Shui¹, Shicheng Hao¹, Yiwen Lai¹, Lei Miao¹, Qiujuan Wang⁴, Xiaoseng Guo⁴, Li Yuan¹()

¹ Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, China & Collaborative Innovation Center of Judicial Civilization, Beijing 100088, China
² Guangdong Nantian Institute of Forensic Science, Shenzhen 518045, China
³ Beijing Tianping Judicial Expert Center, Beijing 100025, China
⁴ BGI Forensic, Shenzhen 518083, China

Received:2025-08-13 Revised:2025-10-28 Published:2026-05-20 Online:2025-11-14
Supported by:
Research and Innovation Project of China University of Political Science and Law(24KYGH017);Fundamental Research Funds for the Central Universities;Opening Project of Guangdong Provincial Forensic Science of Evidence Materials (Nantian) Engineering Technology Research Center(ETRC202401)

摘要/Abstract

摘要：

在涉及突变、近亲和亲缘关系鉴定中，需要检验更多的短串联重复序列(short tandem repeat, STR)。然而既往群体研究几乎限于40个以内STR，为此本研究调查了81个常染色体STR基因座在中国北方汉族人群中的遗传多态性、连锁不平衡和突变率情况，确认了STR基因座的核心重复结构，并重点评价了《法庭科学 DNA数据库选用的基因座及其数据结构》(GB/T 41009-2021)中C类和该标准外新增21个STR基因座法医学应用价值。首先，采集400份中国北方汉族健康无关个体血样以及157个家系中父母与孩子血样，利用GSTAR ^TM25以及新研制的GSTAR ^TM31FS和GSTAR ^TM29HS试剂盒进行检测，对81个常染色体STR基因座分型数据进行遗传学分析。本研究对新增的15个STR基因座经测序明确核心序列结构。结果显示，81个常染色体STR基因座经Bonferroni校正之后均符合Hardy-Weinberg平衡，杂合度观测值在0.4375~0.9075之间，个体识别率在0.6332~0.9845之间(LPL基因座最低)，多态性信息含量在0.3938~0.9092之间，三联体非父排除率在0.1384~0.8108之间，二联体非父排除率在0.0955~0.7069之间，D5S2500与D5S2800基因座之间存在连锁不平衡，在不统计D5S2800基因座情形下，80个常染色体STR基因座的累积个体识别率为1-2.293×10^-89，三联体累积非父排除率为1-5.074×10^-31，二联体累积非父排除率为1-1.400×10^-19。观察157个家系中508次减数分裂，在10个STR基因座上有13次突变，D5S818、D11S2368和D18S51基因座突变率为0.004，D6S1043、D7S1517、D11S4463、D13S325、D14S1434、D20S482和D20S85基因座突变率为0.002。结果表明，本研究使用的81个STR基因座多态性为良好或中等，适用于个体识别、亲子鉴定和亲缘关系鉴定。鉴于D5S2500与D5S2800基因座之间存在连锁不平衡，在毛细管电泳平台同时检验时建议仅用D5S2500基因座的检验结果进行统计学分析。本研究提供了大数量STR的等位基因频率数据、突变率，且明确了STR的核心序列，为DNA证据力评估提供重要的数据基础。

关键词: 法医遗传学, 短串联重复片段, 遗传多态性, 北方汉族

Abstract:

Examining a greater number of short tandem repeats (STRs) is essential for cases involving mutations, consanguinity, and complex kinship testing. However, previous population studies were mostly limited to fewer than 40 STRs. Therefore, this study investigated the genetic polymorphism, linkage disequilibrium, and mutation rates of 81 autosomal STR loci in the Han Chinese population of northern China. We confirmed the core repeat structure of STR loci, and focused on evaluating the forensic application value of the Category C and 21 additional STR loci not included in the standard “Forensic science-Data structures of selected loci from the DNA database” (GB/T 41009-2021). Blood samples from 400 unrelated healthy Northern Han Chinese individuals and parent-child blood samples from 157 families were detected using GSTAR ^TM25, GSTAR ^TM31FS, and GSTAR ^TM29HS kits. Genetic analysis was performed on genotyping data of 81 autosomal STR loci. The core sequence structures of newly added 15 STR loci were confirmed by sequencing the allelic ladder. After applying Bonferroni correction, all 81 autosomal STR loci conformed to Hardy-Weinberg equilibrium. The observed heterozygosity ranged from 0.4375 to 0.9075, discrimination power from 0.6332 to 0.9845 (lowest at LPL), polymorphism information content from 0.3938 to 0.9092, probability of exclusion for trios from 0.1384 to 0.8108, and for duos from 0.0955 to 0.7069. Significantly, linkage disequilibrium was observed between D5S2500 and D5S2800 loci. When excluding the D5S2800 locus, the cumulative discrimination power (CDP) of remaining 80 autosomal STR loci was 1-2.293×10^-89, cumulative probability of exclusion (CPE) of trios was 1-5.074×10^-31, and cumulative exclusion probability of duos was 1-1.400×10^-19. A total of 13 mutations were observed across 508 meiotic events in 157 families at 10 STR loci. The mutation rates for D5S818, D11S2368 and D18S51 were 0.004, while those of D6S1043, D7S1517, D11S4463, D13S325, D14S1434, D20S482 and D20S85 were 0.002. In conclusion, the 81 genetic loci, including Category C and newly added STRs, exhibit good or moderate polymorphism and are suitable for individual identification, paternity testing, and kinship identification. Given the linkage disequilibrium between the D5S2500 and D5S2800, if simultaneous on the capillary electrophoresis platform, it is recommended to use only the test results from the D5S2500 locus for statistical analysis. This data generated provide allele frequency and mutation rate for a large number of STRs, along with the clarified core sequences, thus offering an important data foundation for DNA evidence evaluation.

Key words: forensic genetics, short tandem repeat, genetic polymorphism, Northern Han

贺航, 张金佩, 张楚楚, 姜成涛, 税薇薇, 郝世诚, 来宜雯, 缪磊, 王秋娟, 郭小森, 袁丽. 中国北方汉族人群81个常染色体STR基因座多态性研究及突变调查[J]. 遗传, 2026, 48(5): 483-505.

Hang He, Jinpei Zhang, Chuchu Zhang, Chengtao Jiang, Weiwei Shui, Shicheng Hao, Yiwen Lai, Lei Miao, Qiujuan Wang, Xiaoseng Guo, Li Yuan. Genetic polymorphism and mutation analysis of 81 autosomal STR loci in the Northern Han Chinese population[J]. Hereditas(Beijing), 2026, 48(5): 483-505.

图/表 10

表1

表2

附图1

表3

81个常染色体STR基因座信息"

基因座	GRCh38染色体位置	重复结构	9948分型	基因座分类
D1S1627	Chr1:106421092~106421130	[ATT]_a	11,13	C
D1S1656	Chr1:230769616~230769683	[CCTA]_a[TCTA]_b	14,17	B
D1S1677	Chr1:163590026~163590085	[TTCC]_a	13,14	C
D1S2142	Chr1:212260251~212260318	[GGAT]_a[AGAT]_b	14,17	-
D1S549	Chr1:219470400~219470427	[CTAT]_a	14,15	-
D1GATA113	Chr1:7382831~7382874	[GATA]_a	7,12	C
TPOX	Chr2:1489653~1489684	[AATG]_a	8,9	A
D2S1338	Chr2:218014859~218014950	[GGAA]_a[GGCA]_b	23	A
D2S1360	Chr2:17310718~17310801	[AGAT]_a[AGAC]_b[AGAT]_c	22,25	-
D2S1772	Chr2:66824006~66824108	[CTAT]_a[GTATCTAT]_b[CTAT]_cCTGTCTATCTGTCTAT	21,29	-
D2S1776	Chr2:168788893~168788936	[AGAT]_a	10,12	C
D2S441	Chr2:68011947~68011994	[TCTA]_a	11,12	B
D3S1358	Chr3:45540739~45540802	[TCTA]_a[TCTG]_b[TCTA]_c	15,17	A
D3S1545	Chr3:161955366~161955393	[TATC]_a	12,14	-
D3S1744	Chr3:147374752~147374828	[ATAG]_aATG[ATAG]_bAT[ATAG]_c	18	C
D3S2459	Chr3:102456546~102456593	[TATC]_a	12	-
D3S3045	Chr3:107271167~107271224	[AGAT]_aAT[AGAT]_b	12,14	B
D3S3053	Chr3:172033175~172033210	[GATA]_a	9,12	-
D3S4529	Chr3:85803483~85803534	[AGAT]_aAAAT[AGAT]_b	12	C
FGA	Chr4:154587736~154587823	[GGAA]_aGGAG[AAAG]_bAGAAAAAA[GAAA]_c	24,26	A
D4S2364	Chr4:92596222~92596257	[ATTC]_aATCCATTC	9,10	-
D4S2366	Chr4:6483114~6483161	[GATA]_a[GATT]_b[GATA]_c	9,14	C
D4S2408	Chr4:31302798~31302833	[ATCT]_a	10	C
CSF1PO	Chr5:150076324~150076375	[ATCT]_a	10,11	A
D5S1505	Chr5:119766041~119766134	[TATC]_a[TATT]_b[TATC]_c[TATT]_d[TATC]_e	24.2, 25.2	-
D5S2500	Chr5:59401444~59401487	[CTAT]_a	11,15	C
D5S2800	Chr5:59403132~59403199	[GGTA]_a[GACA]_b[GATA]_c[GATT]_d	14,17	C
D5S818	Chr5:123775556~123775599	[ATCT]_a	11,13	A
D6S1017	Chr6:41709531~41709570	[GGAT]_a	8	C
D6S1043	Chr6:91740225~91740272	[ATCT]_a	12	A
D6S474	Chr6:112557951~112558018	[AGAT]_a[GATA]_b[GGTA]_c[GACA]_d	17	C
D6S477	Chr6:6140394~6140465	[TCTA]_aTA[TCTA]₂TATCTA[TCTG]_b[TCTA]_c	11,16	B
D7S1517	Chr7:123857645~123857732	[CTTT]_aGTTT[CTTT]_b[GTTT]_c[CTTT]_d	20,22	C
D7S3048	Chr7:21227082~21227174	[TATC]_aN₁₃[TATC]_b[TACC]_c [CACC]_d	23	C
D7S820	Chr7:84160226~84160277	[TATC]_a	11	A
D8S1115	Chr8:42681448~42681471	[TAA]_a	14,16	-
D8S1132	Chr8:106316692~106316774	[TCTA]_aTCA[TCTA]_b	20,24	B
D8S1179	Chr8:124894865~124894916	[TCTA]_a[TCTG]_b[TCTA]_c	12,13	A
LPL	Chr8:19957989~19958032	[TTTA]_a	10,12	-
D9S1118	Chr9:31925370~31925420	[TATC]_a	8,12.3	-
D9S1122	Chr9:77073826~77073873	[TAGA]_a	12,15	C
D9S925	Chr9:18289137~18289192	[CTAT]_a[CTAC]_b[CTAT]_c	15,16	C
D10S1248	Chr10:129294244~129294295	[GGAA]_a	12,15	B
D10S1435	Chr10:2201138~2201181	[TATC]_a	12,13	B
D10S2325	Chr10:12751052~12751126	[ATAAG]_a	8,14	-
TH01	Chr11:2171088~2171115	[AATG]_a	6,9.3	A
D11S2368	Chr11:19259601~19259684	[TATC]_a[TGTC]_b[TATC]_c	21	C
D11S4463	Chr11:131002511~131002566	[TATC]_aTATGTATC	12,14	C
vWA	Chr12:5983977~5984044	[TAGA]_a[CAGA]_bTAGA	17	A
D12S1064	Chr12:90429573~90429628	[TCTT]_a[TCTA]_b[TCTG]_c[TCTA]_d	18,20	-
D12S391	Chr12:12297020~12297095	[AGAT]_a[AGAC]_b[AGAT]_c	18,24	A
D13S305	Chr13:36451854~36451918	[CTTT]_a	17,20	-
D13S317	Chr13:82148025~82148068	[TATC]_a	11	A
D13S325	Chr13:42599304~42599382	[TCTA]_aTCA[TCTA]_b	19,20	C
D14S1434	Chr14:94842054~94842105	[CTGT]_a[CTAT]_b	13,14	C
D14S608	Chr14:28380295~28380330	[GATA]_a	12	C
Penta E	Chr15:96831015~96831039	[TCTTT]_a	11	A
D15S659	Chr15:46081911~46081966	[TATC]_a	16,18	B
D16S3391	Chr16:52282054~52282101	[TCTA]_a	10,13	-
D16S539	Chr16:86352702~86352745	[GATA]_a	11	A
D17S1290	Chr17:58254109~58254192	[AGAT]_aN₂₈[ATAG]_b	14,15	C
D17S1301	Chr17:74684855 ~74684902	[AGAT]_a	11,12	C
D17S974	Chr17:10615439~10615474	[ATAG]_a	10,11	C
D18S1364	Chr18:65732998~65733057	[TAGA]_aTACA[TAGA]_b	13,14	C
D18S51	Chr18:63281667~63281738	[AGAA]_a	15,18	A
D18S535	Chr18:40568879~40568930	[GATA]_a	13,15	C
D19S253	Chr19:15617484~15617531	[ATCT]_a	11,12	B
D19S400	Chr19:41021664~41021707	[TCTA]_a	12,13	-
D19S433	Chr19:29926235~29926298	[CCTT]_aCCTA[CCTT]_bCTTT[CCTT]_c	13,14	A
D20S1082	Chr20:55249399~55249440	[ATA]_a	11,15	C
D20S161	Chr20:16641475~16641550	[ATAG]_a[GTAG]_b[CTAG]_c[ATAG]_d	17,18	-
D20S470	Chr20:17391907~17391946	[AGGA]_a	6,13	C
D20S482	Chr20:4525692~4525747	[AGAT]_a	13,14	C
D20S85	Chr20:39423111~39423170	[TTTC]_a	13,17	-
Penta D	Chr21:43636205~43636269	[AAAGA]_a	8,12	A
D21S11	Chr21:19181973~19182099	[TCTA]_a[TCTG]_b[TCTA]_cTA[TCTA]_dTCA [TCTA]_eTCCATA[TCTA]_f	29,30	A
D21S1270	Chr21:30334488~30334556	[ATAG]_aATG[ATAG]_bATG[ATAG]_c	13.3,15	C
D21S1442	Chr21:27446264~27446342	[GATA]_a[GACA]_b[GATA]_c	20.3, 21.3	-
D22GATA198B05	Chr22:17169807~17169882	[CTAT]_a[CTCT]_b[ATCT]_c[ACCT]_d	18,21	C
D22S1045	Chr22:37140287~37140337	[ATT]_aACT[ATT]_b	16,18	B
D22S684	Chr22:34199631~34199728	[TATC]_a[TGTC]_b[TATC]_c[CATC]_dATCTATTTAT [TATC]_e	23,27	-

表3

表4

北方汉族人群81个常染色体STR基因座的等位基因频率"

等位基因	D1S1627	D1S1656	D1S1677	D1S2142	D1S549	D1GATA113	TPOX
7						0.4813	0.0038
8						0.0050	0.5063
9		0.0013					0.1300
10	0.0500	0.0038	0.0025				0.0213
11		0.0650	0.0013		0.0650	0.1563	0.3050
12	0.0913	0.0438	0.0288	0.3388	0.1688	0.3200	0.0325
13	0.5438	0.1075	0.0988	0.1138	0.0875	0.0375	0.0013
14	0.2963	0.0613	0.4725	0.0425	0.2800
14.3		0.0013
15	0.0163	0.2875	0.3250	0.2188	0.3225
15.3		0.0025
16	0.0025	0.2500	0.0638	0.1775	0.0688
16.3		0.0025
17		0.0838	0.0075	0.0963	0.0075
17.3		0.0563
18		0.0088		0.0125
18.3		0.0225
19		0.0013
19.3		0.0013
等位基因	D2S1338	D2S1360	D2S1772	D2S1776	D2S441	D3S1358	D3S1545
7				0.0013			0.0888
8				0.0025	0.0013
9				0.1450
9.1					0.0225
10				0.0775	0.2400		0.0250
11				0.3125	0.3438		0.2313
11.3					0.0338
12				0.3475	0.1938	0.0013	0.3463
12.1				0.0013
12.3					0.0013
13				0.0775	0.0313	0.0050	0.2225
13.2					0.0013
14				0.0325	0.1250	0.0550	0.0788
15				0.0025	0.0050	0.3675	0.0075
16	0.0100				0.0013	0.3125
17	0.0688		0.0125			0.1850
18	0.1350		0.0125			0.0663
19	0.1638	0.0125	0.0225			0.0075
20	0.1325	0.0113	0.0675
21	0.0313	0.1750	0.1063
22	0.0450	0.6075	0.0813
23	0.2075	0.0900	0.0125
24	0.1250	0.0325	0.2650
25	0.0638	0.0213	0.0688
26	0.0138	0.0175	0.0588
27	0.0013	0.0138	0.1625
28	0.0025	0.0088	0.1100
29		0.0063	0.0188
30		0.0038	0.0013
等位基因	D3S1744	D3S2459	D3S3045	D3S3053	D3S4529	D4S2364	D4S2366
7				0.0025		0.0238
8		0.0325		0.0013		0.2000
9			0.3363	0.4013		0.4200	0.3200
10		0.0075	0.0225	0.0825		0.3538	0.0375
11		0.1863	0.0300	0.3150		0.0025	0.3725
12		0.3163	0.1475	0.1800			0.1263
13	0.0263	0.1750	0.1963	0.0163	0.1963		0.0750
14	0.0875	0.1738	0.1950	0.0013	0.2175		0.0650
15	0.1000	0.0925	0.0650		0.3913		0.0038
16	0.1075	0.0150	0.0063		0.1538
17	0.3213		0.0013		0.0400
18	0.1888	0.0013			0.0013
19	0.1200
20	0.0388
21	0.0075
22	0.0025
等位基因	D4S2408	FGA	CSF1PO	D5S1505	D5S2500	D5S2800	D5S818
7			0.0013				0.0163
8	0.2338		0.0013				0.0025
9	0.3063		0.0463		0.0063		0.0838
10	0.2763		0.1963		0.0125		0.1650
11	0.1513		0.2650		0.2700		0.3088
12	0.0263		0.3588		0.1575		0.2688
13	0.0038		0.1063		0.0425		0.1450
14	0.0025		0.0225	0.0038	0.0688	0.4288	0.0088
15			0.0013		0.3300		0.0013
16			0.0013		0.0913
16.2		0.0013
17		0.0013			0.0200	0.2575
18		0.0200			0.0013	0.2225
19		0.0500				0.0025
20		0.0238				0.0713
20.2				0.0088
21		0.1000
21.2		0.0025		0.0400
22		0.1663
22.2		0.0088		0.0800
23		0.2138				0.0175
23.2		0.0150		0.1488
24		0.2088
24.2		0.0138		0.2688
25		0.1088
25.2		0.0025		0.2250
26		0.0463
26.2				0.1475
27		0.0150
27.2				0.0563
28		0.0013
28.2				0.0200
29		0.0013
29.2				0.0013
等位基因	D6S1017	D6S1043	D6S474	D6S477	D7S1517	D7S3048	D7S820
8	0.2150	0.0013					0.1138
9	0.0013	0.0013					0.0550
9.1							0.0013
10	0.4275	0.0250		0.0088			0.1625
10.1							0.0013
11	0.0313	0.0913	0.0025	0.0063			0.3388
11.2				0.0013
12	0.2650	0.1500		0.0650			0.2700
13	0.0513	0.1400	0.0013	0.1988			0.0513
14	0.0063	0.1250	0.3588	0.2063			0.0063
15	0.0025	0.0138	0.3675	0.2963	0.0013
16		0.0025	0.1188	0.1675	0.0050	0.0013
17		0.0338	0.1225	0.0413	0.0050	0.0100
18		0.1738	0.0250	0.0075	0.0113	0.1050
19		0.1713	0.0038	0.0013	0.0738	0.1000
20		0.0613			0.1275	0.1338
20.1						0.0013
20.3		0.0038
21		0.0063			0.1363	0.1263
22					0.1438	0.0825
23					0.1438	0.1788
23.3						0.0013
24					0.1088	0.1613
25					0.1738	0.0800
26					0.0400	0.0163
26.1					0.0013
27					0.0163	0.0025
28					0.0125
等位基因	D8S1115	D8S1132	D8S1179	LPL	D9S1118	D9S1122	D9S925
7				0.0050
8	0.2113		0.0013	0.0013	0.1700	0.0025
9	0.0025		0.0025	0.0088	0.0250	0.0038
10	0.0050		0.1075	0.7313	0.0025	0.0513
11	0.0013		0.0800	0.0863	0.0100	0.1650
11.3					0.1650
12	0.0025		0.1288	0.1638	0.0025	0.3350
12.3					0.1663
13	0.0300		0.2275	0.0025		0.3475	0.0113
13.3					0.0313
14	0.0388		0.1813			0.0788	0.1613
14.3					0.2338
15	0.4588		0.1513	0.0013		0.0163	0.2100
15.3					0.1688		0.0025
16	0.1775	0.0138	0.0825				0.2863
16.3					0.0250		0.0213
17	0.0538	0.1000	0.0263				0.2138
17.3							0.0050
18	0.0150	0.1763	0.0088				0.0838
19	0.0038	0.2013	0.0025				0.0050
20		0.1563
21		0.1500
22		0.1150
23		0.0625
24		0.0175
25		0.0063
26		0.0013
等位基因	D10S1248	D10S1435	D10S2325	TH01	D11S2368	D11S4463	vWA
6			0.0250	0.0888
7		0.0013	0.2888	0.3000
7.2						0.0013
8		0.0413	0.0313	0.0638		0.0013
9		0.0025	0.0688	0.4825		0.0063
9.3				0.0438
10		0.0313	0.0950	0.0213
10.3		0.0013
11		0.1525	0.1375			0.0025
11.3		0.0013
12	0.0750	0.3563	0.1413			0.0513
13	0.4188	0.2575	0.0950			0.2438
14	0.2088	0.1325	0.0463			0.3275	0.2375
15	0.1938	0.0188	0.0263		0.0025	0.2538	0.0300
16	0.0888	0.0025	0.0088		0.0263	0.0900	0.2100
16.3		0.0013
17	0.0138		0.0050		0.1463	0.0188	0.2475
18	0.0013		0.0063		0.1150	0.0038	0.1700
18.2			0.0013
19			0.0013		0.1763		0.0875
20			0.0063		0.1863		0.0163
20.4			0.0013
21			0.0038		0.2100		0.0013
22			0.0025		0.0800
23			0.0013		0.0413
24			0.0013		0.0150
25			0.0025		0.0013
26			0.0038
等位基因	D12S1064	D12S391	D13S305	D13S317	D13S325	D14S1434	D14S608
6							0.0525
7							0.2163
8				0.2500			0.0188
9				0.1375		0.0013	0.1050
10				0.1463		0.0813	0.2175
11				0.2563		0.1438	0.2338
11.2			0.0013
12			0.0038	0.1688		0.0275	0.1125
13	0.0250		0.0038	0.0300		0.2675	0.0363
14	0.0563		0.0275	0.0113	0.0013	0.4463	0.0075
14.2			0.0013
15	0.0450	0.0113	0.0450			0.0288
15.2			0.0013
16	0.1063	0.0038	0.0813			0.0038
16.2			0.0013
17	0.2700	0.0750	0.1688		0.0063
18	0.3538	0.2013	0.2338		0.0388
18.2		0.0013
18.3		0.0013	0.0013
19	0.1088	0.2413	0.2263		0.2700
20	0.0300	0.1875	0.1338		0.2850
21	0.0038	0.1225	0.0550		0.2063
22	0.0013	0.0800	0.0113		0.1138
23		0.0500	0.0038		0.0513
24		0.0150			0.0163
25		0.0100			0.0088
26					0.0013
27.3					0.0013
等位基因	Penta E	D15S659	D16S3391	D16S539	D17S1290	D17S1301	D17S974
5	0.0513			0.0025
6				0.0013			0.0013
7	0.0050					0.0063	0.0263
8	0.0025			0.0063		0.0038	0.1550
9	0.0013	0.0013	0.0225	0.2325	0.0488	0.0250	0.2125
10	0.0313	0.0038	0.1913	0.1388	0.0513	0.0363	0.3925
11	0.1450	0.0200	0.0625	0.2200	0.0163	0.1688	0.1825
11.3						0.0013
12	0.1025	0.1525	0.1725	0.2425	0.0063	0.4650	0.0263
13	0.0513	0.2463	0.3088	0.1263	0.0075	0.2300	0.0038
14	0.1050	0.1200	0.1863	0.0288	0.2513	0.0550
15	0.0863	0.0438	0.0538	0.0013	0.2650	0.0088
16	0.0800	0.1288	0.0025		0.1725
17	0.0975	0.1875			0.1075
18	0.0750	0.0838			0.0450
18.4	0.0013
19	0.0588	0.0100			0.0213
19.4	0.0013
20	0.0463	0.0025			0.0063
21	0.0250				0.0013
22	0.0225
23	0.0063
24	0.0038
25	0.0013
等位基因	D18S1364	D18S51	D18S535	D19S253	D19S400	D19S433	D20S1082
6			0.0013		0.0013
7				0.1463
8				0.0325	0.1475
9			0.1588	0.0063	0.0575		0.0025
10			0.0500	0.0175	0.0563	0.0013	0.0025
11		0.0050	0.0300	0.1475	0.3363	0.0050	0.3938
12	0.0388	0.0350	0.1113	0.3463	0.1863	0.0413	0.0275
12.2						0.0050
13	0.1813	0.1738	0.2513	0.2200	0.0700	0.3050	0.0075
13.2						0.0475
14	0.2013	0.2263	0.2825	0.0725	0.0775	0.2513	0.0338
14.2						0.1138
15	0.1888	0.1850	0.1088	0.0113	0.0550	0.0638	0.3850
15.2						0.1200
16	0.1750	0.1188	0.0063		0.0125	0.0113	0.1363
16.2						0.0300
17	0.0475	0.0900					0.0113
17.2						0.0050
18	0.0875	0.0425
19	0.0563	0.0363
20	0.0200	0.0350
21	0.0038	0.0275
22		0.0150
23		0.0063
24		0.0013
26		0.0013
27		0.0013
等位基因	D20S161	D20S470	D20S482	D20S85	D21S11	D21S1270	D21S1442
6		0.0025
7				0.0050
8		0.0013
9		0.0288	0.0013
10		0.1350	0.0263	0.3625		0.0013
10.3						0.0025
11		0.0313	0.0050	0.0138		0.3013
11.3						0.0013
12		0.0413	0.0513	0.0775		0.0638
13		0.1275	0.2713	0.1138		0.0525
13.3						0.0813
14		0.1600	0.3950	0.1638		0.0838
14.3						0.0375
15	0.0675	0.1538	0.1875	0.1588		0.2525
15.3						0.0138
16	0.2138	0.1525	0.0600	0.0913		0.0988
16.3	0.0013					0.0025	0.0013
17	0.3700	0.1138	0.0025	0.0138		0.0075
17.3							0.0063
18	0.1363	0.0350
18.3							0.0225
19	0.1263	0.0163
19.3							0.0713
20	0.0775	0.0013
20.3							0.1300
21	0.0063
21.3							0.2913
22	0.0013
22.3							0.2775
23.2							0.0025
23.3							0.1088
24.3							0.0538
25.3							0.0213
26.3							0.0138
27					0.0013
28					0.0438
28.2					0.0063
29					0.2613
30					0.2988
30.2					0.0150
30.3					0.0013
31					0.1013
31.2					0.0700
32					0.0288
32.1					0.0025
32.2					0.1163
33					0.0025
33.2					0.0425
34.2					0.0088
等位基因	Penta D	D22GATA198B05	D22S1045	D22S684
6	0.0038
7	0.0088
8	0.0538
9	0.3150
10	0.1025
11	0.1613		0.2475
12	0.1775		0.0063
13	0.1350		0.0063
14	0.0413	0.0063	0.0113
15	0.0013	0.0263	0.2688
16		0.0563	0.2550
17		0.1488	0.1863
18		0.0750	0.0175	0.0050
19		0.0900	0.0013	0.0263
20		0.1088		0.2900
21		0.3038		0.2688
22		0.1500		0.1750
23		0.0263		0.1250
24		0.0088		0.0850
25				0.0225
26				0.0025

表4

附表1

北方汉族人群81个常染色体STR基因座的基因型频率"

基因型		基因型		基因型		基因型
D1S1627		D1S1656		D1S1677		D1S2142
G	F	G	F	G	F	G	F
10,12	0.0025	9,13	0.0025	10,14	0.0050	12,12	0.1175
10,13	0.0725	10,11	0.0025	11,14	0.0025	12,13	0.0675
10,14	0.0250	10,16	0.0025	12,12	0.0025	12,14	0.0350
12,12	0.0025	10,17.3	0.0025	12,13	0.0100	12,15	0.1400
12,13	0.1250	11,11	0.0100	12,14	0.0250	12,16	0.1125
12,14	0.0425	11,12	0.0025	12,15	0.0125	12,17	0.0750
12,15	0.0075	11,13	0.0150	12,16	0.0025	12,18	0.0125
13,13	0.2675	11,14	0.0025	12,17	0.0025	13,13	0.0125
13,14	0.3450	11,15	0.0200	13,13	0.0150	13,14	0.0150
13,15	0.0100	11,16	0.0525	13,14	0.0725	13,15	0.0625
14,14	0.0800	11,17	0.0125	13,15	0.0675	13,16	0.0400
14,15	0.0150	11,17.3	0.0025	13,16	0.0175	13,17	0.0175
14,16	0.0050	12,12	0.0050	14,14	0.2450	14,15	0.0100
D1S549		12,13	0.0100	14,15	0.2975	14,16	0.0175
G	F	12,14	0.0025	14,16	0.0450	14,17	0.0075
11,11	0.0050	12,15	0.0375	14,17	0.0075	15,15	0.0425
11,12	0.0175	12,16	0.0150	15,15	0.1100	15,16	0.0875
11,13	0.0150	12,17	0.0075	15,16	0.0500	15,17	0.0450
11,14	0.0350	12,18	0.0025	15,17	0.0025	15,18	0.0075
11,15	0.0450	13,13	0.0050	16,16	0.0050	16,16	0.0250
11,16	0.0075	13,14	0.0100	16,17	0.0025	16,17	0.0425
12,12	0.0400	13,15	0.0725	D1GATA113		16,18	0.0050
12,13	0.0325	13,16	0.0425	G	F	17,17	0.0025
12,14	0.0750	13,17	0.0225	7,7	0.2350	TPOX
12,15	0.1100	13,17.3	0.0200	7,11	0.1675	G	F
12,16	0.0225	13,18	0.0025	7,12	0.2850	7,8	0.0025
13,13	0.0025	13,18.3	0.0050	7,13	0.0400	7,11	0.0050
13,14	0.0650	13,19	0.0025	8,11	0.0025	8,8	0.2500
13,15	0.0425	14,14	0.0050	8,12	0.0075	8,9	0.1475
13,16	0.0150	14,15	0.0450	11,11	0.0200	8,10	0.0225
14,14	0.0600	14,16	0.0375	11,12	0.0975	8,11	0.3000
14,15	0.2250	14,17	0.0100	11,13	0.0050	8,12	0.0400
14,16	0.0375	14,17.3	0.0050	12,12	0.1100	9,9	0.0175
14,17	0.0025	14.3,16	0.0025	12,13	0.0300	9,10	0.0050
15,15	0.0900	15,15	0.0900	D2S1772		9,11	0.0600
15,16	0.0375	15,15.3	0.0025	G	F	9,12	0.0125
15,17	0.0050	15,16	0.1350	17,24	0.0100	10,11	0.0150
16,16	0.0050	15,16.3	0.0025	17,25	0.0025	11,11	0.1075
16,17	0.0075	15,17	0.0375	17,26	0.0025	11,12	0.0125
D2S1338		15,17.3	0.0275	17,27	0.0025	11,13	0.0025
G	F	15,18	0.0050	17,28	0.0050	D2S1776
16,17	0.0025	15,18.3	0.0100	17,29	0.0025	G	F
16,19	0.0050	15.3,16	0.0025	18,18	0.0025	7,12	0.0025
16,23	0.0050	16,16	0.0575	18,24	0.0050	8,11	0.0025
16,24	0.0050	16,17	0.0400	18,25	0.0025	8,12.1	0.0025
16,25	0.0025	16,17.3	0.0225	18,26	0.0050	9,9	0.0275
17,17	0.0025	16,18	0.0075	18,27	0.0050	9,10	0.0200
17,18	0.0150	16,18.3	0.0225	18,28	0.0025	9,11	0.0850
17,19	0.0250	16,19.3	0.0025	19,20	0.0050	9,12	0.1025
17,20	0.0200	16.3,17.3	0.0025	19,21	0.0075	9,13	0.0200
17,21	0.0025	17,17	0.0100	19,22	0.0025	9,14	0.0075
17,22	0.0025	17,17.3	0.0125	19,24	0.0050	10,10	0.0050
17,23	0.0350	17,18.3	0.0050	19,25	0.0025	10,11	0.0425
17,24	0.0150	17.3,17.3	0.0075	19,26	0.0025	10,12	0.0625
17,25	0.0100	17.3,18.3	0.0025	19,27	0.0100	10,13	0.0175
17,26	0.0050	D2S1360		19,28	0.0075	10,14	0.0025
18,18	0.0150	G	F	19,29	0.0025	11,11	0.1175
18,19	0.0450	19,21	0.0025	20,21	0.0100	11,12	0.1900
18,20	0.0375	19,22	0.0100	20,22	0.0125	11,13	0.0400
18,21	0.0100	19,23	0.0050	20,24	0.0575	11,14	0.0275
18,22	0.0100	19,24	0.0025	20,25	0.0050	11,15	0.0025
18,23	0.0600	19,28	0.0025	20,27	0.0250	12,12	0.1225
18,24	0.0525	19,30	0.0025	20,28	0.0150	12,13	0.0625
18,25	0.0075	20,21	0.0025	20,29	0.0050	12,14	0.0275
18,26	0.0025	20,22	0.0150	21,21	0.0150	12,15	0.0025
19,19	0.0275	20,23	0.0050	21,22	0.0150	13,13	0.0075
19,20	0.0425	21,21	0.0125	21,23	0.0025	D2S441
19,21	0.0075	21,22	0.2450	21,24	0.0450	G	F
19,22	0.0175	21,23	0.0325	21,25	0.0100	8,11	0.0025
19,23	0.0775	21,24	0.0125	21,26	0.0225	9.1,10	0.0225
19,24	0.0300	21,25	0.0050	21,27	0.0425	9.1,11	0.0150
19,25	0.0200	21,26	0.0175	21,28	0.0175	9.1,11.3	0.0025
19,26	0.0025	21,27	0.0050	21,29	0.0075	9.1,12	0.0025
20,20	0.0250	21,30	0.0025	21,30	0.0025	9.1,14	0.0025
20,21	0.0025	22,22	0.3550	22,22	0.0075	10,10	0.0600
20,22	0.0125	22,23	0.1125	22,23	0.0025	10,11	0.1625
20,23	0.0425	22,24	0.0300	22,24	0.0500	10,11.3	0.0150
20,24	0.0250	22,25	0.0350	22,25	0.0100	10,12	0.0900
20,25	0.0200	22,26	0.0125	22,26	0.0125	10,13	0.0175
20,26	0.0075	22,27	0.0150	22,27	0.0275	10,14	0.0500
20,27	0.0025	22,28	0.0150	22,28	0.0125	10,15	0.0025
20,28	0.0025	22,29	0.0125	22,29	0.0025	11,11	0.1250
21,21	0.0025	22,30	0.0025	23,24	0.0050	11,11.3	0.0175
21,22	0.0075	23,23	0.0050	23,25	0.0100	11,12	0.1350
21,23	0.0200	23,24	0.0075	23,27	0.0025	11,12.3	0.0025
21,24	0.0025	23,26	0.0025	23,28	0.0025	11,13	0.0125
21,25	0.0050	23,27	0.0050	24,24	0.0725	11,14	0.0850
22,23	0.0175	24,24	0.0025	24,25	0.0250	11,15	0.0025
22,24	0.0150	24,25	0.0025	24,26	0.0225	11,16	0.0025
22,25	0.0075	24,26	0.0025	24,27	0.0900	11.3,12	0.0175
23,23	0.0325	24,27	0.0025	24,28	0.0650	11.3,14	0.0150
23,24	0.0575	D3S1545		24,29	0.0050	12,12	0.0325
23,25	0.0275	G	F	25,25	0.0075	12,13	0.0175
23,26	0.0050	7,7	0.0025	25,26	0.0025	12,13.2	0.0025
23,28	0.0025	7,10	0.0075	25,27	0.0275	12,14	0.0550
24,24	0.0125	7,11	0.0475	25,28	0.0225	12,15	0.0025
24,25	0.0225	7,12	0.0675	25,29	0.0025	13,13	0.0025
25,26	0.0050	7,13	0.0350	26,26	0.0050	13,14	0.0075
D3S1358		7,14	0.0150	26,27	0.0200	13,15	0.0025
G	F	10,10	0.0025	26,28	0.0150	14,14	0.0175
12,17	0.0025	10,11	0.0075	26,29	0.0025	D3S3045
13,15	0.0050	10,12	0.0175	27,27	0.0250	G	F
13,16	0.0025	10,13	0.0050	27,28	0.0150	9,9	0.1025
13,18	0.0025	10,14	0.0075	27,29	0.0075	9,10	0.0150
14,14	0.0050	11,11	0.0575	28,28	0.0200	9,11	0.0150
14,15	0.0325	11,12	0.1400	D3S1744		9,12	0.1150
14,16	0.0350	11,13	0.1175	G	F	9,13	0.1450
14,17	0.0225	11,14	0.0275	13,16	0.0075	9,14	0.1225
14,18	0.0100	11,15	0.0075	13,17	0.0200	9,15	0.0500
15,15	0.1300	12,12	0.1300	13,18	0.0100	9,16	0.0050
15,16	0.2225	12,13	0.1525	13,19	0.0075	10,11	0.0050
15,17	0.1475	12,14	0.0525	13,20	0.0075	10,12	0.0025
15,18	0.0600	12,15	0.0025	14,14	0.0025	10,13	0.0100
15,19	0.0075	13,13	0.0500	14,15	0.0150	10,14	0.0125
16,16	0.1050	13,14	0.0300	14,16	0.0225	11,12	0.0075
16,17	0.1100	13,15	0.0050	14,17	0.0600	11,13	0.0075
16,18	0.0425	14,14	0.0125	14,18	0.0400	11,14	0.0150
16,19	0.0025	D3S4529		14,19	0.0225	11,15	0.0100
17,17	0.0375	G	F	14,20	0.0050	12,12	0.0275
17,18	0.0100	13,13	0.0300	14,21	0.0050	12,13	0.0425
17,19	0.0025	13,14	0.1100	15,15	0.0175	12,14	0.0550
18,18	0.0025	13,15	0.1575	15,16	0.0225	12,15	0.0150
18,19	0.0025	13,16	0.0525	15,17	0.0700	12,16	0.0025
D3S3053		13,17	0.0125	15,18	0.0375	13,13	0.0375
G	F	14,14	0.0450	15,19	0.0050	13,14	0.0875
7,11	0.0050	14,15	0.1500	15,20	0.0100	13,15	0.0225
8,9	0.0025	14,16	0.0650	15,21	0.0025	13,16	0.0025
9,9	0.1650	14,17	0.0200	15,22	0.0025	14,14	0.0350
9,10	0.0725	15,15	0.1575	16,16	0.0125	14,15	0.0225
9,11	0.2350	15,16	0.1325	16,17	0.0550	14,16	0.0025
9,12	0.1450	15,17	0.0250	16,18	0.0400	14,17	0.0025
9,13	0.0175	15,18	0.0025	16,19	0.0375	15,15	0.0050
10,10	0.0025	16,16	0.0175	16,20	0.0025	D3S2459
10,11	0.0625	16,17	0.0225	16,22	0.0025	G	F
10,12	0.0250	D4S2366		17,17	0.1025	13,13	0.0325
11,11	0.1025	G	F	17,18	0.1175	13,14	0.0725
11,12	0.1100	9,9	0.0800	17,19	0.0850	13,15	0.0325
11,13	0.0100	9,10	0.0375	17,20	0.0250	13,16	0.0050
11,14	0.0025	9,11	0.2600	17,21	0.0050	14,14	0.0300
12,12	0.0400	9,12	0.0925	18,18	0.0375	14,15	0.0325
13,13	0.0025	9,13	0.0475	18,19	0.0350	14,16	0.0075
D4S2364		9,14	0.0425	18,20	0.0200	14,18	0.0025
G	F	10,11	0.0200	18,21	0.0025	15,15	0.0025
7,8	0.0075	10,12	0.0100	19,19	0.0225	FGG
7,9	0.0225	10,13	0.0050	19,20	0.0025	G	F
7,10	0.0175	10,14	0.0025	20,20	0.0025	16.2,22	0.0025
8,8	0.0450	11,11	0.1400	D4S2408		17,26	0.0025
8,9	0.1800	11,12	0.0875	G	F	18,21	0.0025
8,10	0.1225	11,13	0.0475	8,8	0.0600	18,22	0.0100
9,9	0.1450	11,14	0.0500	8,9	0.1325	18,23	0.0050
9,10	0.3475	12,12	0.0075	8,10	0.1175	18,24	0.0050
10,10	0.1075	12,13	0.0275	8,11	0.0825	18,25	0.0125
10,11	0.0050	12,14	0.0150	8,12	0.0150	18,26	0.0050
CSF1PO		12,15	0.0050	9,9	0.0950	19,19	0.0025
G	F	13,13	0.0050	9,10	0.1850	19,20	0.0025
7,11	0.0025	13,14	0.0100	9,11	0.0875	19,21	0.0050
8,12	0.0025	13,15	0.0025	9,12	0.0150	19,22	0.0250
9,9	0.0050	14,14	0.0050	9,13	0.0025	19,23	0.0275
9,10	0.0250	D5S1505		10,10	0.0775	19,23.2	0.0025
9,11	0.0175	G	F	10,11	0.0750	19,24	0.0175
9,12	0.0325	14,23.2	0.0025	10,12	0.0150	19,24.2	0.0075
9,13	0.0075	14,24.2	0.0025	10,13	0.0050	19,25	0.0050
10,10	0.0525	14,25.2	0.0025	11,11	0.0250	19,26	0.0025
10,11	0.0800	20.2,23.2	0.0050	11,12	0.0075	20,21	0.0075
10,12	0.1300	20.2,24.2	0.0025	14,14	0.0025	20,22	0.0100
10,13	0.0475	20.2,25.2	0.0050	D5S2500		20,23	0.0150
10,14	0.0050	20.2,26.2	0.0025	G	F	20,23.2	0.0025
11,11	0.0775	20.2,27.2	0.0025	9,12	0.0025	20,24.2	0.0025
11,12	0.2150	21.2,21.2	0.0025	9,14	0.0025	20,25	0.0025
11,13	0.0500	21.2,22.2	0.0075	9,15	0.0075	20,27	0.0050
11,14	0.0075	21.2,23.2	0.0075	10,11	0.0075	21,21	0.0100
11,15	0.0025	21.2,24.2	0.0200	10,12	0.0025	21,21.2	0.0025
12,12	0.1250	21.2,25.2	0.0175	10,14	0.0025	21,22	0.0300
12,13	0.0675	21.2,26.2	0.0175	10,15	0.0100	21,22.2	0.0050
12,14	0.0175	21.2,27.2	0.0050	10,16	0.0025	21,23	0.0425
12,16	0.0025	22.2,23.2	0.0300	11,11	0.0625	21,24	0.0300
13,13	0.0150	22.2,24.2	0.0450	11,12	0.0900	21,24.2	0.0075
13,14	0.0100	22.2,25.2	0.0350	11,13	0.0100	21,25	0.0325
14,14	0.0025	22.2,26.2	0.0175	11,14	0.0225	21,26	0.0075
D5S818		22.2,27.2	0.0175	11,15	0.2100	21,27	0.0025
G	F	22.2,28.2	0.0075	11,16	0.0700	21,28	0.0025
7,9	0.0025	23.2,23.2	0.0200	11,17	0.0050	21,29	0.0025
7,10	0.0075	23.2,24.2	0.0850	12,12	0.0300	21.2,24	0.0025
7,11	0.0075	23.2,25.2	0.0500	12,13	0.0225	22,22	0.0325
7,12	0.0150	23.2,26.2	0.0425	12,14	0.0200	22,22.2	0.0025
8,11	0.0025	23.2,27.2	0.0300	12,15	0.0950	22,23	0.0525
8,13	0.0025	23.2,28.2	0.0050	12,16	0.0175	22,24	0.0775
9,9	0.0050	24.2,24.2	0.0650	12,17	0.0050	22,25	0.0350
9,10	0.0400	24.2,25.2	0.1225	13,14	0.0050	22,25.2	0.0025
9,11	0.0400	24.2,26.2	0.1000	13,15	0.0350	22,26	0.0150
9,12	0.0450	24.2,27.2	0.0150	13,16	0.0075	22,27	0.0050
9,13	0.0250	24.2,28.2	0.0125	13,17	0.0050	22.2,23	0.0075
9,14	0.0050	24.2,29.2	0.0025	14,14	0.0075	22.2,26	0.0025
10,10	0.0225	25.2,25.2	0.0500	14,15	0.0500	23,23	0.0400
10,11	0.1000	25.2,26.2	0.0775	14,16	0.0150	23,23.2	0.0125
10,12	0.0925	25.2,27.2	0.0300	14,17	0.0050	23,24	0.0950
10,13	0.0425	25.2,28.2	0.0100	15,15	0.0950	23,24.2	0.0050
10,14	0.0025	26.2,26.2	0.0125	15,16	0.0450	23,25	0.0450
11,11	0.1125	26.2,27.2	0.0100	15,17	0.0150	23,26	0.0275
11,12	0.1575	26.2,28.2	0.0025	15,18	0.0025	23,27	0.0125
11,13	0.0825	27.2,28.2	0.0025	16,16	0.0100	23.2,24	0.0050
11,14	0.0025	D5S2800		16,17	0.0050	23.2,25	0.0050
12,12	0.0750	G	F	D6S1043		23.2,26	0.0025
12,13	0.0700	14,14	0.1650	G	F	24,24	0.0500
12,14	0.0050	14,17	0.2400	8,14	0.0025	24,24.2	0.0050
12,15	0.0025	14,18	0.2050	9,18	0.0025	24,25	0.0600
13,13	0.0325	14,19	0.0025	10,12	0.0100	24,25.2	0.0025
13,14	0.0025	14,20	0.0700	10,13	0.0025	24,26	0.0175
D6S1017		14,23	0.0100	10,14	0.0125	25,25	0.0050
G	F	17,17	0.0675	10,18	0.0100	25,26	0.0050
8,8	0.0500	17,18	0.1075	10,19	0.0050	25,27	0.0050
8,10	0.1800	17,20	0.0200	10,20	0.0075	26,26	0.0025
8,11	0.0125	17,23	0.0125	10,21	0.0025	D6S474
8,12	0.1150	18,18	0.0425	11,11	0.0025	G	F
8,13	0.0150	18,20	0.0375	11,12	0.0275	11,11	0.0025
8,14	0.0050	18,23	0.0100	11,13	0.0275	13,17	0.0025
8,15	0.0025	19,23	0.0025	11,14	0.0225	14,14	0.1350
9,10	0.0025	20,20	0.0075	11,15	0.0100	14,15	0.2775
10,10	0.1725	D6S477		11,17	0.0075	14,16	0.0775
10,11	0.0275	G	F	11,18	0.0275	14,17	0.0750
10,12	0.2450	11,13	0.0025	11,19	0.0425	14,18	0.0175
10,13	0.0475	11,14	0.0025	11,20	0.0100	15,15	0.1150
10,14	0.0050	11,15	0.0025	11,21	0.0025	15,16	0.0875
10,15	0.0025	11,16	0.0050	12,12	0.0175	15,17	0.1200
11,12	0.0175	11.2,15	0.0025	12,13	0.0400	15,18	0.0175
11,13	0.0025	12,13	0.0225	12,14	0.0625	15,19	0.0025
11,14	0.0025	12,14	0.0375	12,17	0.0075	16,16	0.0200
12,12	0.0575	12,15	0.0400	12,18	0.0525	16,17	0.0200
12,13	0.0375	12,16	0.0225	12,19	0.0575	16,18	0.0100
D7S1517		12,17	0.0050	12,20	0.0075	16,19	0.0025
G	F	13,13	0.0300	13,13	0.0100	17,17	0.0100
15,20	0.0025	13,14	0.0950	13,14	0.0400	17,18	0.0050
16,20	0.0025	13,15	0.1100	13,17	0.0100	17,19	0.0025
16,23	0.0025	13,16	0.0775	13,18	0.0575	D8S1115
16,24	0.0050	13,17	0.0225	13,19	0.0550	G	F
17,19	0.0025	13,18	0.0025	13,20	0.0200	8,8	0.0525
17,20	0.0025	14,14	0.0425	13,20.3	0.0025	8,11	0.0025
17,24	0.0025	14,15	0.1025	13,21	0.0050	8,12	0.0025
17,27	0.0025	14,16	0.0675	14,14	0.0100	8,13	0.0100
18,19	0.0025	14,17	0.0125	14,15	0.0075	8,14	0.0100
18,20	0.0050	14,18	0.0100	14,17	0.0025	8,15	0.1900
18,21	0.0025	15,15	0.1025	14,18	0.0500	8,16	0.0875
18,23	0.0050	15,16	0.0925	14,19	0.0175	8,17	0.0075
18,25	0.0025	15,17	0.0275	14,20	0.0125	8,18	0.0075
18,26	0.0025	15,18	0.0025	15,19	0.0075	9,15	0.0025
18,28	0.0025	16,16	0.0275	15,20	0.0025	9,16	0.0025
19,19	0.0075	16,17	0.0100	16,17	0.0025	10,14	0.0025
19,20	0.0125	16,19	0.0025	16,20	0.0025	10,15	0.0075
19,21	0.0300	17,17	0.0025	17,18	0.0100	12,15	0.0025
19,22	0.0150	D7S3048		17,19	0.0225	13,15	0.0375
19,23	0.0150	G	F	17,20	0.0050	13,16	0.0100
19,24	0.0175	16,18	0.0025	18,18	0.0200	13,17	0.0025
19,25	0.0300	17,19	0.0025	18,19	0.0675	14,15	0.0400
19,26	0.0050	17,20	0.0050	18,20	0.0250	14,16	0.0100
19,27	0.0025	17,21	0.0025	18,20.3	0.0050	14,17	0.0100
20,20	0.0100	17,22	0.0025	19,19	0.0250	14,18	0.0050
20,21	0.0275	17,23	0.0050	19,20	0.0150	15,15	0.2175
20,22	0.0475	17,24	0.0025	19,21	0.0025	15,16	0.1425
20,23	0.0400	18,18	0.0125	20,20	0.0075	15,17	0.0450
20,24	0.0225	18,19	0.0200	D7S820		15,18	0.0150
20,25	0.0600	18,20	0.0225	G	F	16,16	0.0300
20,26	0.0075	18,21	0.0200	8,8	0.0075	16,17	0.0325
20,27	0.0050	18,22	0.0250	8,9	0.0175	16,18	0.0025
21,21	0.0125	18,23	0.0425	8,10	0.0500	16,19	0.0075
21,22	0.0450	18,24	0.0400	8,11	0.0800	17,17	0.0050
21,23	0.0525	18,25	0.0100	8,12	0.0575	LPL
21,24	0.0150	18,26	0.0025	8,13	0.0050	G	F
21,25	0.0550	19,19	0.0050	8,14	0.0025	7,10	0.0025
21,26	0.0125	19,20	0.0225	9,9	0.0025	7,12	0.0075
21,27	0.0025	19,21	0.0200	9,10	0.0200	8,11	0.0025
21,28	0.0050	19,22	0.0150	9,11	0.0425	9,10	0.0075
22,22	0.0275	19,23	0.0550	9,12	0.0200	9,11	0.0050
22,23	0.0450	19,24	0.0325	9,13	0.0025	9,12	0.0050
22,24	0.0300	19,25	0.0175	9,14	0.0025	10,10	0.5350
22,25	0.0400	19,26	0.0050	9.1,12	0.0025	10,11	0.1250
22,26	0.0050	20,20	0.0125	10,10	0.0275	10,12	0.2525
22,26.1	0.0025	20,20.1	0.0025	10,11	0.1025	10,13	0.0050
22,28	0.0025	20,21	0.0400	10,12	0.0850	11,11	0.0075
23,23	0.0175	20,22	0.0200	10,13	0.0125	11,12	0.0225
23,24	0.0225	20,23	0.0425	10.1,12	0.0025	11,15	0.0025
23,25	0.0425	20,24	0.0575	11,11	0.1125	12,12	0.0200
23,26	0.0150	20,25	0.0250	11,12	0.1800	D8S1132
23,27	0.0050	20,26	0.0025	11,13	0.0450	G	F
23,28	0.0075	20,27	0.0025	11,14	0.0025	16,17	0.0050
24,24	0.0200	21,21	0.0200	12,12	0.0850	16,18	0.0100
24,25	0.0375	21,22	0.0300	12,13	0.0225	16,19	0.0075
24,26	0.0150	21,23	0.0425	13,13	0.0050	16,22	0.0025
24,27	0.0075	21,24	0.0425	13,14	0.0050	16,23	0.0025
24,28	0.0025	21,25	0.0100	D8S1179		17,17	0.0100
25,25	0.0250	21,26	0.0050	G	F	17,18	0.0325
25,26	0.0175	22,22	0.0050	8,15	0.0025	17,19	0.0450
25,27	0.0075	22,23	0.0175	9,10	0.0025	17,20	0.0300
25,28	0.0050	22,24	0.0225	9,15	0.0025	17,21	0.0325
D9S1118		22,25	0.0200	10,10	0.0100	17,22	0.0200
G	F	22,26	0.0025	10,11	0.0275	17,23	0.0100
11.3,11.3	0.0250	23,23	0.0325	10,12	0.0400	17,24	0.0050
11.3,12.3	0.0600	23,24	0.0525	10,13	0.0550	18,18	0.0300
11.3,13.3	0.0175	23,25	0.0325	10,14	0.0325	18,19	0.0700
11.3,14.3	0.0650	23,27	0.0025	10,15	0.0250	18,20	0.0525
11.3,15.3	0.0600	23.3,26	0.0025	10,16	0.0125	18,21	0.0600
11.3,16.3	0.0100	24,24	0.0150	11,11	0.0100	18,22	0.0400
12,14.3	0.0025	24,25	0.0350	11,12	0.0275	18,23	0.0225
12,16.3	0.0025	24,26	0.0075	11,13	0.0300	18,24	0.0025
12.3,12.3	0.0325	25,25	0.0025	11,14	0.0225	18,26	0.0025
12.3,13.3	0.0100	25,26	0.0050	11,15	0.0225	19,19	0.0325
12.3,14.3	0.0800	D9S1122		11,16	0.0075	19,20	0.0475
12.3,15.3	0.0425	G	F	11,17	0.0025	19,21	0.0650
12.3,16.3	0.0175	8,12	0.0025	12,12	0.0125	19,22	0.0550
13.3,14.3	0.0100	8,13	0.0025	12,13	0.0600	19,23	0.0400
13.3,15.3	0.0075	9,10	0.0025	12,14	0.0400	19,24	0.0050
14.3,14.3	0.0675	9,13	0.0050	12,15	0.0500	19,25	0.0025
14.3,15.3	0.0750	10,10	0.0025	12,16	0.0125	20,20	0.0275
14.3,16.3	0.0075	10,11	0.0050	12,17	0.0025	20,21	0.0575
15.3,15.3	0.0350	10,12	0.0350	13,13	0.0450	20,22	0.0375
15.3,16.3	0.0050	10,13	0.0500	13,14	0.0875	20,23	0.0200
D9S925		10,14	0.0025	13,15	0.0750	20,24	0.0075
G	F	10,15	0.0025	13,16	0.0425	20,25	0.0050
13,14	0.0050	11,11	0.0325	13,17	0.0150	21,21	0.0125
13,16	0.0075	11,12	0.1050	14,14	0.0450	21,22	0.0375
13,17	0.0075	11,13	0.1150	14,15	0.0550	21,23	0.0125
13,18	0.0025	11,14	0.0350	14,16	0.0275	21,24	0.0075
14,14	0.0225	11,15	0.0050	14,17	0.0050	21,25	0.0025
14,15	0.0775	12,12	0.1100	14,18	0.0025	22,22	0.0100
14,15.3	0.0025	12,13	0.2600	15,15	0.0175	22,23	0.0125
14,16	0.0950	12,14	0.0400	15,16	0.0250	22,24	0.0050
14,16.3	0.0050	12,15	0.0075	15,17	0.0100	23,23	0.0025
14,17	0.0625	13,13	0.0975	16,16	0.0100	24,25	0.0025
14,17.3	0.0025	13,14	0.0600	16,17	0.0075	TH01
14,18	0.0275	13,15	0.0075	16,18	0.0050	G	F
15,15	0.0550	14,14	0.0075	16,19	0.0050	6,6	0.0125
15,15.3	0.0025	14,15	0.0050	17,17	0.0025	6,7	0.0450
15,16	0.0825	15,15	0.0025	17,18	0.0050	6,8	0.0075
15,16.3	0.0100	D10S1248		18,18	0.0025	6,9	0.0900
15,17	0.1100	G	F	D10S1435		6,9.3	0.0100
15,18	0.0225	12,12	0.0075	G	F	7,7	0.1000
15,19	0.0050	12,13	0.0550	7,12	0.0025	7,8	0.0475
16,16	0.0950	12,14	0.0225	8,11	0.0225	7,9	0.2825
16,16.3	0.0175	12,15	0.0450	8,12	0.0350	7,9.3	0.0200
16,17	0.1200	12,16	0.0125	8,13	0.0150	7,10	0.0050
16,17.3	0.0050	13,13	0.2000	8,14	0.0025	8,9	0.0575
16,18	0.0500	13,14	0.1600	8,15	0.0025	8,9.3	0.0100
16,19	0.0050	13,15	0.1425	8,16	0.0050	8,10	0.0050
16.3,17	0.0075	13,16	0.0675	9,12	0.0025	9,9	0.2350
16.3,18	0.0025	13,17	0.0100	9,13	0.0025	9,9.3	0.0375
17,17	0.0400	13,18	0.0025	10,11	0.0125	9,10	0.0275
17,17.3	0.0025	14,14	0.0575	10,12	0.0250	9.3,9.3	0.0050
17,18	0.0375	14,15	0.0725	10,13	0.0200	10,10	0.0025
18,18	0.0125	14,16	0.0400	10,14	0.0050	vWG
D10S2325		14,17	0.0075	10.3,11	0.0025	G	F
G	F	15,15	0.0325	11,11	0.0200	14,14	0.0425
6,7	0.0150	15,16	0.0525	11,12	0.0875	14,15	0.0175
6,9	0.0025	15,17	0.0100	11,13	0.0750	14,16	0.0950
6,10	0.0075	16,16	0.0025	11,14	0.0575	14,17	0.1425
6,12	0.0050	D11S2368		11,15	0.0075	14,18	0.0800
6,13	0.0075	G	F	11.3,13	0.0025	14,19	0.0425
6,14	0.0025	15,18	0.0025	12,12	0.1175	14,20	0.0100
6,15	0.0025	15,23	0.0025	12,13	0.2075	14,21	0.0025
6,17	0.0025	16,17	0.0050	12,14	0.0975	15,15	0.0025
6,18	0.0025	16,18	0.0075	12,15	0.0200	15,16	0.0175
6,23	0.0025	16,19	0.0050	13,13	0.0725	15,17	0.0050
7,7	0.0900	16,20	0.0100	13,14	0.0400	15,18	0.0100
7,8	0.0150	16,21	0.0100	13,15	0.0050	15,19	0.0050
7,9	0.0375	16,22	0.0075	13,16.3	0.0025	16,16	0.0325
7,10	0.0575	16,23	0.0050	14,14	0.0300	16,17	0.1150
7,11	0.0900	16,24	0.0025	14,15	0.0025	16,18	0.0825
7,12	0.0775	17,17	0.0125	D11S4463		16,19	0.0400
7,13	0.0450	17,18	0.0225	G	F	16,20	0.0050
7,14	0.0275	17,19	0.0700	7.2,15	0.0025	17,17	0.0625
7,15	0.0100	17,20	0.0525	8,12	0.0025	17,18	0.0625
7,16	0.0025	17,21	0.0625	9,13	0.0025	17,19	0.0350
7,17	0.0025	17,22	0.0325	9,14	0.0025	17,20	0.0100
7,18	0.0075	17,23	0.0175	9,15	0.0075	18,18	0.0350
7,20	0.0025	17,24	0.0050	11,13	0.0025	18,19	0.0300
7,21	0.0050	18,18	0.0150	11,14	0.0025	18,20	0.0050
7,22	0.0025	18,19	0.0350	12,12	0.0100	19,19	0.0100
8,9	0.0050	18,20	0.0350	12,13	0.0300	19,20	0.0025
8,10	0.0050	18,21	0.0625	12,14	0.0300	D12S1064
8,11	0.0100	18,22	0.0200	12,15	0.0150	G	F
8,12	0.0075	18,23	0.0100	12,16	0.0050	13,13	0.0025
8,13	0.0075	18,24	0.0050	13,13	0.0575	13,14	0.0025
8,14	0.0075	19,19	0.0400	13,14	0.1550	13,15	0.0025
8,16	0.0025	19,20	0.0750	13,15	0.1325	13,17	0.0175
8,20	0.0025	19,21	0.0625	13,16	0.0375	13,18	0.0200
9,10	0.0225	19,22	0.0125	13,17	0.0100	13,19	0.0025
9,11	0.0175	19,23	0.0050	13,18	0.0025	14,15	0.0025
9,12	0.0200	19,24	0.0075	14,14	0.1050	14,16	0.0075
9,13	0.0075	20,20	0.0375	14,15	0.1750	14,17	0.0300
9,14	0.0075	20,21	0.0900	14,16	0.0550	14,18	0.0450
9,15	0.0050	20,22	0.0175	14,17	0.0225	14,19	0.0150
9,16	0.0050	20,23	0.0100	14,18	0.0025	14,20	0.0075
9,17	0.0025	20,24	0.0050	15,15	0.0525	14,21	0.0025
9,25	0.0025	20,25	0.0025	15,16	0.0675	15,16	0.0125
9,26	0.0025	21,21	0.0325	15,18	0.0025	15,17	0.0325
10,10	0.0075	21,22	0.0425	16,16	0.0050	15,18	0.0300
10,11	0.0325	21,23	0.0200	16,17	0.0050	15,19	0.0050
10,12	0.0200	21,24	0.0050	D12S391		15,20	0.0050
10,13	0.0075	22,22	0.0075	G	F	16,16	0.0100
10,14	0.0075	22,23	0.0125	15,17	0.0050	16,17	0.0600
10,15	0.0100	D13S305		15,18	0.0025	16,18	0.0800
10,16	0.0025	G	F	15,19	0.0025	16,19	0.0300
10,19	0.0025	11.2,13	0.0025	15,20	0.0050	16,20	0.0025
11,11	0.0175	12,17	0.0025	15,21	0.0050	17,17	0.0675
11,12	0.0350	12,18	0.0025	15,22	0.0025	17,18	0.1825
11,13	0.0200	12,20	0.0025	16,19	0.0025	17,19	0.0625
11,14	0.0150	13,18	0.0025	16,20	0.0025	17,20	0.0175
11,15	0.0100	13,20	0.0025	16,25	0.0025	17,22	0.0025
11,16	0.0025	14,14	0.0025	17,17	0.0075	18,18	0.1300
11,17	0.0025	14,16	0.0025	17,18	0.0475	18,19	0.0625
11,22	0.0025	14,17	0.0075	17,19	0.0350	18,20	0.0225
11,24	0.0025	14,18	0.0175	17,20	0.0250	18,21	0.0050
12,12	0.0225	14,19	0.0150	17,21	0.0100	19,19	0.0175
12,13	0.0425	14,20	0.0075	17,22	0.0075	19,20	0.0050
12,14	0.0100	14.2,20	0.0025	17,23	0.0050	D13S325
12,15	0.0075	15,15	0.0025	18,18	0.0400	G	F
12,16	0.0025	15,16	0.0100	18,18.3	0.0025	14,19	0.0025
12,18.2	0.0025	15,17	0.0200	18,19	0.0925	17,19	0.0050
12,20.4	0.0025	15,18	0.0275	18,20	0.0675	17,21	0.0025
12,25	0.0025	15,19	0.0150	18,21	0.0475	17,22	0.0050
12,26	0.0025	15,20	0.0075	18,22	0.0300	18,18	0.0025
13,13	0.0125	15,21	0.0050	18,23	0.0275	18,19	0.0100
13,14	0.0150	15.2,19	0.0025	18,24	0.0050	18,20	0.0275
13,15	0.0075	16,16	0.0075	18.2,19	0.0025	18,21	0.0200
13,20	0.0025	16,17	0.0300	19,19	0.0725	18,22	0.0050
13,26	0.0025	16,18	0.0325	19,20	0.0925	18,23	0.0050
18,20	0.0025	16,19	0.0425	19,21	0.0400	18,24	0.0050
20,21	0.0025	16,20	0.0150	19,22	0.0350	19,19	0.0800
D13S317		16,21	0.0100	19,23	0.0225	19,20	0.1500
G	F	16,22	0.0050	19,24	0.0075	19,21	0.1025
8,8	0.0475	16.2,22	0.0025	19,25	0.0050	19,22	0.0700
8,9	0.0675	17,17	0.0350	20,20	0.0375	19,23	0.0200
8,10	0.0825	17,18	0.0725	20,21	0.0550	19,24	0.0075
8,11	0.1500	17,19	0.0775	20,22	0.0225	19,25	0.0100
8,12	0.0850	17,20	0.0400	20,23	0.0150	19,27.3	0.0025
8,13	0.0150	17,21	0.0150	20,24	0.0075	20,20	0.0750
8,14	0.0050	17,23	0.0025	20,25	0.0075	20,21	0.1450
9,9	0.0350	18,18	0.0450	21,21	0.0125	20,22	0.0625
9,10	0.0325	18,18.3	0.0025	21,22	0.0350	20,23	0.0250
9,11	0.0400	18,19	0.1150	21,23	0.0225	20,24	0.0075
9,12	0.0575	18,20	0.0650	21,24	0.0025	20,25	0.0025
9,13	0.0075	18,21	0.0250	21,25	0.0025	21,21	0.0300
10,10	0.0275	18,22	0.0150	22,22	0.0075	21,22	0.0500
10,11	0.0575	19,19	0.0525	22,23	0.0025	21,23	0.0250
10,12	0.0500	19,20	0.0625	22,24	0.0075	21,24	0.0050
10,13	0.0075	19,21	0.0150	22,25	0.0025	21,26	0.0025
10,14	0.0075	19,23	0.0025	23,23	0.0025	22,22	0.0075
11,11	0.0725	20,20	0.0125	PentGE		22,23	0.0125
11,12	0.0925	20,21	0.0350	G	F	22,24	0.0050
11,13	0.0200	20,23	0.0025	5,5	0.0025	22,25	0.0025
11,14	0.0075	21,21	0.0025	5,7	0.0025	23,23	0.0075
12,12	0.0225	D14S608		5,10	0.0100	24,25	0.0025
12,13	0.0075	G	F	5,11	0.0125	D15S659
13,14	0.0025	6,7	0.0250	5,12	0.0025	G	F
D14S1434		6,8	0.0025	5,13	0.0125	9,14	0.0025
G	F	6,9	0.0075	5,14	0.0175	10,13	0.0025
9,14	0.0025	6,10	0.0225	5,15	0.0050	10,16	0.0025
10,10	0.0100	6,11	0.0275	5,16	0.0075	10,19	0.0025
10,11	0.0225	6,12	0.0100	5,17	0.0100	11,12	0.0050
10,12	0.0025	6,13	0.0100	5,18	0.0100	11,15	0.0025
10,13	0.0425	7,7	0.0625	5,21	0.0050	11,16	0.0175
10,14	0.0725	7,8	0.0075	5,23	0.0025	11,17	0.0075
10,15	0.0025	7,9	0.0475	7,11	0.0050	11,18	0.0075
11,11	0.0175	7,10	0.0875	7,18	0.0025	12,12	0.0175
11,12	0.0025	7,11	0.0800	8,11	0.0025	12,13	0.0925
11,13	0.0725	7,12	0.0450	8,16	0.0025	12,14	0.0250
11,14	0.1450	7,13	0.0100	9,12	0.0025	12,15	0.0125
11,15	0.0075	7,14	0.0050	10,10	0.0075	12,16	0.0375
11,16	0.0025	8,9	0.0075	10,11	0.0025	12,17	0.0625
12,13	0.0150	8,10	0.0050	10,12	0.0050	12,18	0.0300
12,14	0.0300	8,11	0.0075	10,14	0.0050	12,19	0.0050
12,15	0.0050	8,12	0.0050	10,15	0.0075	13,13	0.0625
13,13	0.0700	8,13	0.0025	10,16	0.0050	13,14	0.0475
13,14	0.2375	9,9	0.0100	10,17	0.0025	13,15	0.0250
13,15	0.0250	9,10	0.0525	10,18	0.0025	13,16	0.0575
13,16	0.0025	9,11	0.0525	10,19	0.0050	13,17	0.0975
14,14	0.1925	9,12	0.0125	10,20	0.0025	13,18	0.0400
14,15	0.0175	9,13	0.0100	11,11	0.0225	13,19	0.0050
14,16	0.0025	10,10	0.0425	11,12	0.0325	14,14	0.0150
D16S3391		10,11	0.1125	11,13	0.0175	14,15	0.0125
G	F	10,12	0.0550	11,14	0.0225	14,16	0.0350
9,10	0.0100	10,13	0.0125	11,15	0.0250	14,17	0.0475
9,12	0.0100	10,14	0.0025	11,16	0.0200	14,18	0.0375
9,13	0.0075	11,11	0.0525	11,17	0.0375	14,20	0.0025
9,14	0.0100	11,12	0.0600	11,18	0.0225	15,15	0.0050
9,15	0.0075	11,13	0.0200	11,19	0.0125	15,16	0.0125
10,10	0.0425	11,14	0.0025	11,20	0.0075	15,17	0.0075
10,11	0.0100	12,12	0.0150	11,21	0.0100	15,18	0.0050
10,12	0.0750	12,13	0.0050	11,22	0.0150	16,16	0.0175
10,13	0.1225	12,14	0.0025	12,12	0.0100	16,17	0.0425
10,14	0.0625	13,14	0.0025	12,13	0.0150	16,18	0.0125
10,15	0.0150	D16S539		12,14	0.0100	16,19	0.0050
10,16	0.0025	G	F	12,15	0.0200	17,17	0.0450
11,11	0.0125	5,10	0.0025	12,16	0.0175	17,18	0.0200
11,12	0.0100	5,12	0.0025	12,17	0.0275	18,18	0.0050
11,13	0.0425	6,11	0.0025	12,18	0.0150	18,19	0.0025
11,14	0.0350	8,9	0.0025	12,19	0.0125	18,20	0.0025
11,15	0.0025	8,11	0.0025	12,20	0.0125	D17S1301
12,12	0.0225	8,12	0.0050	12,21	0.0100	G	F
12,13	0.1125	8,13	0.0025	12,22	0.0025	7,11	0.0025
12,14	0.0750	9,9	0.0550	13,14	0.0125	7,12	0.0050
12,15	0.0175	9,10	0.0650	13,15	0.0075	7,13	0.0025
13,13	0.0875	9,11	0.1150	13,16	0.0050	7,14	0.0025
13,14	0.1175	9,12	0.1200	13,17	0.0050	8,9	0.0025
13,15	0.0375	9,13	0.0475	13,18	0.0050	8,11	0.0025
13,16	0.0025	9,14	0.0050	13,19	0.0125	8,12	0.0025
14,14	0.0275	10,10	0.0150	13,20	0.0075	9,10	0.0075
14,15	0.0175	10,11	0.0550	13,25	0.0025	9,11	0.0025
15,15	0.0050	10,12	0.0550	14,14	0.0150	9,12	0.0200
D17S974		10,13	0.0575	14,15	0.0300	9,13	0.0150
G	F	10,14	0.0125	14,16	0.0125	9,14	0.0025
6,10	0.0025	11,11	0.0475	14,17	0.0225	10,11	0.0050
7,7	0.0025	11,12	0.1075	14,18	0.0150	10,12	0.0450
7,8	0.0075	11,13	0.0400	14,19	0.0100	10,13	0.0125
7,9	0.0200	11,14	0.0225	14,20	0.0150	10,14	0.0025
7,10	0.0125	12,12	0.0650	14,21	0.0025	11,11	0.0225
7,11	0.0075	12,13	0.0500	14,22	0.0050	11,12	0.1650
8,8	0.0275	12,14	0.0125	15,15	0.0050	11,13	0.0925
8,9	0.0675	12,15	0.0025	15,16	0.0100	11,14	0.0225
8,10	0.1050	13,13	0.0250	15,17	0.0175	11.3,13	0.0025
8,11	0.0675	13,14	0.0050	15,18	0.0225	12,12	0.2175
8,12	0.0050	D17S1290		15,19	0.0050	12,13	0.2000
8,13	0.0025	G	F	15,19.4	0.0025	12,14	0.0475
9,9	0.0400	10,11	0.0025	15,20	0.0025	12,15	0.0100
9,10	0.1625	10,12	0.0050	15,21	0.0050	13,13	0.0525
9,11	0.0775	10,15	0.0300	15,23	0.0025	13,14	0.0250
9,12	0.0125	10,16	0.0225	16,16	0.0050	13,15	0.0050
9,13	0.0050	10,17	0.0225	16,17	0.0125	14,14	0.0025
10,10	0.1650	10,18	0.0075	16,18	0.0100	14,15	0.0025
10,11	0.1500	10,19	0.0050	16,19	0.0200	D18S535
10,12	0.0225	10,20	0.0025	16,20	0.0150	G	F
11,11	0.0250	11,12	0.0025	16,21	0.0050	6,13	0.0025
11,12	0.0125	11,15	0.0250	16,22	0.0050	9,9	0.0275
D18S1364		11,16	0.0400	16,24	0.0025	9,10	0.0125
G	F	11,17	0.0100	17,17	0.0100	9,11	0.0125
12,13	0.0175	11,18	0.0125	17,18	0.0100	9,12	0.0325
12,14	0.0150	11,19	0.0050	17,19	0.0150	9,13	0.0850
12,15	0.0125	11,20	0.0025	17,20	0.0025	9,14	0.1000
12,16	0.0125	11,21	0.0025	17,21	0.0075	9,15	0.0150
12,17	0.0100	12,14	0.0025	17,22	0.0050	9,16	0.0050
12,18	0.0050	12,15	0.0025	18,18	0.0075	10,10	0.0025
12,19	0.0050	12,16	0.0025	18,18.4	0.0025	10,12	0.0125
13,13	0.0375	12,17	0.0100	18,19	0.0075	10,13	0.0250
13,14	0.0750	12,18	0.0075	18,21	0.0025	10,14	0.0325
13,15	0.0875	13,16	0.0050	18,22	0.0050	10,15	0.0125
13,16	0.0650	13,18	0.0025	18,24	0.0025	11,12	0.0200
13,17	0.0050	13,19	0.0025	19,20	0.0125	11,13	0.0175
13,18	0.0200	13,20	0.0025	19,22	0.0050	11,14	0.0025
13,19	0.0100	14,14	0.0025	20,20	0.0050	11,15	0.0075
13,20	0.0050	14,15	0.0025	20,23	0.0025	12,12	0.0050
13,21	0.0025	14,16	0.0025	20,24	0.0025	12,13	0.0600
14,14	0.0400	14,17	0.0025	21,22	0.0025	12,14	0.0550
14,15	0.0775	15,15	0.0700	23,23	0.0025	12,15	0.0300
14,16	0.0625	15,16	0.1325	D18S51		12,16	0.0025
14,17	0.0225	15,17	0.0875	G	F	13,13	0.0550
14,18	0.0300	15,18	0.0600	11,13	0.0025	13,14	0.1400
14,19	0.0325	15,19	0.0150	11,14	0.0025	13,15	0.0625
14,20	0.0050	15,20	0.0050	11,15	0.0050	14,14	0.0850
14,21	0.0025	15,21	0.0025	12,13	0.0075	14,15	0.0600
15,15	0.0250	16,16	0.0675	12,14	0.0175	14,16	0.0050
15,16	0.0675	16,17	0.0900	12,15	0.0175	15,15	0.0150
15,17	0.0075	16,18	0.0525	12,16	0.0150	D19S253
15,18	0.0425	16,19	0.0300	12,17	0.0050	G	F
15,19	0.0150	16,20	0.0125	12,19	0.0050	7,7	0.0375
15,20	0.0175	16,21	0.0025	12,20	0.0025	7,8	0.0050
16,16	0.0300	16,22	0.0025	13,13	0.0200	7,9	0.0025
16,17	0.0275	17,17	0.0250	13,14	0.0750	7,11	0.0475
16,18	0.0300	17,18	0.0425	13,15	0.0800	7,12	0.0950
16,19	0.0200	17,19	0.0225	13,16	0.0425	7,13	0.0475
16,20	0.0050	17,20	0.0075	13,17	0.0275	7,14	0.0200
17,17	0.0025	18,18	0.0075	13,18	0.0200	8,8	0.0050
17,18	0.0100	18,19	0.0050	13,19	0.0175	8,11	0.0100
17,19	0.0050	18,20	0.0050	13,20	0.0075	8,12	0.0225
17,20	0.0025	18,21	0.0050	13,21	0.0125	8,13	0.0100
18,18	0.0075	19,20	0.0050	13,22	0.0075	8,14	0.0075
18,19	0.0150	D19S433		13,23	0.0050	9,12	0.0100
18,20	0.0050	G	F	13,24	0.0025	10,11	0.0150
18,21	0.0025	10,14	0.0025	14,14	0.0500	10,12	0.0100
19,19	0.0050	11,12	0.0025	14,15	0.1000	10,13	0.0075
D19S400		11,13	0.0050	14,16	0.0650	10,14	0.0025
G	F	11,15.2	0.0025	14,17	0.0250	11,11	0.0150
6,8	0.0025	12,13	0.0325	14,18	0.0150	11,12	0.1000
8,8	0.0200	12,13.2	0.0075	14,19	0.0100	11,13	0.0575
8,9	0.0125	12,14	0.0150	14,20	0.0175	11,14	0.0275
8,10	0.0200	12,14.2	0.0100	14,21	0.0125	11,15	0.0075
8,11	0.1050	12,15	0.0050	14,22	0.0075	12,12	0.1225
8,12	0.0550	12,15.2	0.0075	14,26	0.0025	12,13	0.1575
8,13	0.0200	12,16.2	0.0025	14,27	0.0025	12,14	0.0425
8,14	0.0200	12.2,13	0.0075	15,15	0.0275	12,15	0.0100
8,15	0.0175	12.2,14.2	0.0025	15,16	0.0250	13,13	0.0575
8,16	0.0025	13,13	0.1000	15,17	0.0325	13,14	0.0425
9,9	0.0100	13,13.2	0.0250	15,18	0.0100	13,15	0.0025
9,10	0.0050	13,14	0.1225	15,19	0.0200	14,15	0.0025
9,11	0.0275	13,14.2	0.0700	15,20	0.0100	D20S1082
9,12	0.0300	13,15	0.0500	15,21	0.0050	G	F
9,13	0.0075	13,15.2	0.0700	15,22	0.0075	9,15	0.0050
9,15	0.0100	13,16	0.0050	15,23	0.0025	10,11	0.0050
9,16	0.0025	13,16.2	0.0225	16,16	0.0150	11,11	0.1450
10,11	0.0400	13.2,13.2	0.0025	16,17	0.0200	11,12	0.0250
10,12	0.0225	13.2,14	0.0325	16,18	0.0075	11,13	0.0025
10,13	0.0075	13.2,14.2	0.0075	16,19	0.0075	11,14	0.0225
10,14	0.0075	13.2,15	0.0100	16,20	0.0150	11,15	0.3125
10,15	0.0075	13.2,15.2	0.0050	16,21	0.0050	11,16	0.1200
10,16	0.0025	13.2,17.2	0.0025	16,22	0.0050	11,17	0.0100
11,11	0.1250	14,14	0.0675	17,17	0.0175	12,15	0.0250
11,12	0.1075	14,14.2	0.0625	17,18	0.0125	12,16	0.0025
11,13	0.0475	14,15	0.0300	17,19	0.0050	12,17	0.0025
11,14	0.0625	14,15.2	0.0725	17,20	0.0050	13,14	0.0025
11,15	0.0250	14,16	0.0050	17,21	0.0075	13,15	0.0100
11,16	0.0075	14,16.2	0.0225	17,22	0.0025	14,14	0.0025
12,12	0.0400	14,17.2	0.0025	17,23	0.0025	14,15	0.0200
12,13	0.0225	14.2,14.2	0.0125	18,18	0.0025	14,16	0.0175
12,14	0.0325	14.2,15	0.0125	18,19	0.0050	15,15	0.1350
12,15	0.0175	14.2,15.2	0.0275	18,20	0.0050	15,16	0.1200
12,16	0.0050	14.2,16	0.0025	18,21	0.0050	15,17	0.0075
13,13	0.0050	14.2,16.2	0.0075	19,20	0.0025	16,16	0.0050
13,14	0.0150	15,15	0.0025	20,21	0.0050	16,17	0.0025
13,15	0.0075	15,15.2	0.0075	21,23	0.0025	D20S85
13,16	0.0025	15,16	0.0025	D20S470		G	F
14,14	0.0025	15,17.2	0.0050	G	F	7,7	0.0025
14,15	0.0125	15.2,15.2	0.0175	6,14	0.0025	7,11	0.0025
15,15	0.0050	15.2,16	0.0075	6,15	0.0025	7,13	0.0025
15,16	0.0025	15.2,16.2	0.0050	8,16	0.0025	10,10	0.1250
D20S482		D20S161		9,9	0.0025	10,11	0.0050
G	F	G	F	9,10	0.0100	10,12	0.0775
9,13	0.0025	15,15	0.0025	9,11	0.0025	10,13	0.0800
10,11	0.0025	15,16	0.0250	9,12	0.0025	10,14	0.1175
10,12	0.0050	15,17	0.0600	9,13	0.0050	10,15	0.1300
10,13	0.0075	15,18	0.0250	9,14	0.0050	10,16	0.0550
10,14	0.0225	15,19	0.0075	9,15	0.0075	10,17	0.0100
10,15	0.0125	15,20	0.0100	9,16	0.0125	11,12	0.0100
10,16	0.0025	15,21	0.0025	9,17	0.0075	11,13	0.0075
11,13	0.0025	16,16	0.0500	10,10	0.0200	11,14	0.0025
11,14	0.0025	16,16.3	0.0025	10,11	0.0175	12,12	0.0050
11,16	0.0025	16,17	0.1475	10,12	0.0125	12,13	0.0125
12,13	0.0275	16,18	0.0675	10,13	0.0150	12,14	0.0225
12,14	0.0375	16,19	0.0450	10,14	0.0375	12,15	0.0150
12,15	0.0225	16,20	0.0400	10,15	0.0375	12,16	0.0050
12,16	0.0100	17,17	0.1350	10,16	0.0450	12,17	0.0025
13,13	0.0825	17,18	0.1025	10,17	0.0325	13,13	0.0075
13,14	0.2175	17,19	0.1025	10,18	0.0150	13,14	0.0450
13,15	0.0875	17,20	0.0500	10,19	0.0075	13,15	0.0350
13,16	0.0325	17,21	0.0075	11,13	0.0050	13,16	0.0275
14,14	0.1575	18,18	0.0125	11,14	0.0075	13,17	0.0025
14,15	0.1475	18,19	0.0275	11,15	0.0100	14,14	0.0150
14,16	0.0450	18,20	0.0225	11,16	0.0150	14,15	0.0675
14,17	0.0025	18,21	0.0025	11,17	0.0050	14,16	0.0350
15,15	0.0425	19,19	0.0225	12,12	0.0025	14,17	0.0075
15,16	0.0175	19,20	0.0225	12,13	0.0050	15,15	0.0200
15,17	0.0025	19,22	0.0025	12,14	0.0225	15,16	0.0275
16,16	0.0050	20,20	0.0050	12,15	0.0125	15,17	0.0025
PentGD		D21S11		12,16	0.0100	16,16	0.0150
G	F	G	F	12,17	0.0125	16,17	0.0025
6,11	0.0025	27,30	0.0025	13,13	0.0250	D21S1442
6,12	0.0025	28,28.2	0.0025	13,14	0.0475	G	F
6,13	0.0025	28,29	0.0300	13,15	0.0450	16.3,22.3	0.0025
7,9	0.0050	28,30	0.0250	13,16	0.0475	17.3,19.3	0.0025
7,12	0.0050	28,30.2	0.0025	13,17	0.0250	17.3,21.3	0.0050
7,13	0.0025	28,31	0.0050	13,18	0.0050	17.3,22.3	0.0025
7,14	0.0050	28,31.2	0.0050	13,19	0.0050	17.3,23.3	0.0025
8,8	0.0050	28,32	0.0050	14,14	0.0150	18.3,19.3	0.0025
8,9	0.0300	28,32.2	0.0050	14,15	0.0575	18.3,20.3	0.0025
8,10	0.0175	28,33.2	0.0050	14,16	0.0475	18.3,21.3	0.0150
8,11	0.0150	28,34.2	0.0025	14,17	0.0450	18.3,22.3	0.0175
8,12	0.0150	28.2,29	0.0075	14,18	0.0075	18.3,23.3	0.0050
8,13	0.0175	28.2,33.2	0.0025	14,19	0.0075	18.3,26.3	0.0025
8,14	0.0025	29,29	0.0625	14,20	0.0025	19.3,19.3	0.0150
9,9	0.1075	29,30	0.1575	15,15	0.0200	19.3,20.3	0.0200
9,10	0.0600	29,30.2	0.0025	15,16	0.0475	19.3,21.3	0.0375
9,11	0.1025	29,31	0.0525	15,17	0.0225	19.3,22.3	0.0300
9,12	0.1100	29,31.2	0.0425	15,18	0.0250	19.3,23.3	0.0125
9,13	0.0875	29,32	0.0175	16,16	0.0175	19.3,24.3	0.0050
9,14	0.0200	29,32.1	0.0025	16,17	0.0375	19.3,26.3	0.0025
10,10	0.0075	29,32.2	0.0550	16,18	0.0025	20.3,20.3	0.0200
10,11	0.0350	29,33.2	0.0250	16,19	0.0025	20.3,21.3	0.0700
10,12	0.0300	29,34.2	0.0050	17,17	0.0150	20.3,22.3	0.0725
10,13	0.0325	30,30	0.0750	17,18	0.0050	20.3,23.3	0.0325
10,14	0.0150	30,30.2	0.0150	17,19	0.0050	20.3,24.3	0.0175
11,11	0.0200	30,30.3	0.0025	18,18	0.0025	20.3,25.3	0.0050
11,12	0.0850	30,31	0.0625	18,19	0.0050	21.3,21.3	0.0750
11,13	0.0275	30,31.2	0.0650	D21S1270		21.3,22.3	0.1750
11,14	0.0125	30,32	0.0125	G	F	21.3,23.3	0.0575
11,15	0.0025	30,32.2	0.0700	9,10	0.0025	21.3,24.3	0.0450
12,12	0.0275	30,33	0.0050	9.3,12	0.0025	21.3,25.3	0.0150
12,13	0.0375	30,33.2	0.0200	9.3,12.3	0.0025	21.3,26.3	0.0125
12,14	0.0150	30,34.2	0.0100	10,10	0.0825	22.3,22.3	0.0750
13,13	0.0250	30.2,31	0.0050	10,11	0.0350	22.3,23.3	0.0650
13,14	0.0125	30.2,31.2	0.0025	10,12	0.0350	22.3,24.3	0.0200
D22GATA198B05		30.2,32	0.0025	10,12.3	0.0525	22.3,25.3	0.0125
G	F	31,31	0.0100	10,13	0.0600	22.3,26.3	0.0075
14,19	0.0025	31,31.2	0.0100	10,13.3	0.0175	23.2,23.2	0.0025
14,20	0.0025	31,32	0.0100	10,14	0.1550	23.3,23.3	0.0100
14,21	0.0025	31,32.1	0.0025	10,14.3	0.0025	23.3,24.3	0.0125
14,22	0.0050	31,32.2	0.0250	10,15	0.0775	23.3,25.3	0.0075
15,15	0.0025	31,33.2	0.0100	10.3,12.3	0.0025	23.3,26.3	0.0025
15,16	0.0050	31.2,31.2	0.0025	11,11	0.0100	24.3,24.3	0.0025
15,17	0.0050	31.2,32.2	0.0075	11,12	0.0025	24.3,25.3	0.0025
15,18	0.0075	31.2,33.2	0.0025	11,12.3	0.0075	D22S684
15,19	0.0075	32,32.2	0.0075	11,13	0.0150	G	F
15,20	0.0025	32,33.2	0.0025	11,13.3	0.0075	18,20	0.0050
15,21	0.0100	32.2,32.2	0.0275	11,14	0.0225	18,21	0.0025
15,22	0.0050	32.2,33.2	0.0075	11,15	0.0175	18,22	0.0025
15,23	0.0050	33.2,33.2	0.0050	12,12	0.0025	19,20	0.0125
16,17	0.0300	D22S1045		12,12.3	0.0075	19,21	0.0150
16,18	0.0050	G	F	12,13	0.0075	19,22	0.0100
16,19	0.0075	11,11	0.0675	12,13.3	0.0025	19,23	0.0050
16,20	0.0150	11,14	0.0025	12,14	0.0275	19,24	0.0050
16,21	0.0350	11,15	0.1325	12,15	0.0125	19,25	0.0050
16,22	0.0150	11,16	0.1275	12,15.3	0.0025	20,20	0.0900
17,17	0.0250	11,17	0.0850	12.3,12.3	0.0125	20,21	0.1525
17,18	0.0225	11,18	0.0100	12.3,13.3	0.0100	20,22	0.1025
17,19	0.0275	11,19	0.0025	12.3,14	0.0425	20,23	0.0675
17,20	0.0250	12,15	0.0050	12.3,14.3	0.0025	20,24	0.0450
17,21	0.0950	12,16	0.0050	12.3,15	0.0100	20,25	0.0150
17,22	0.0400	12,17	0.0025	13,13	0.0050	21,21	0.0700
17,24	0.0025	13,15	0.0025	13,13.3	0.0050	21,22	0.0975
18,18	0.0075	13,16	0.0075	13,14	0.0425	21,23	0.0725
18,19	0.0100	13,17	0.0025	13,14.3	0.0100	21,24	0.0475
18,20	0.0200	14,15	0.0050	13,15	0.0150	21,25	0.0075
18,21	0.0425	14,16	0.0125	13,16	0.0025	21,26	0.0025
18,22	0.0250	14,17	0.0025	13.3,13.3	0.0100	22,22	0.0275
18,23	0.0025	15,15	0.0675	13.3,15	0.0075	22,23	0.0400
19,19	0.0050	15,16	0.1375	13.3,16	0.0050	22,24	0.0325
19,20	0.0100	15,17	0.1050	14,14	0.0800	22,25	0.0075
19,21	0.0650	15,18	0.0150	14,14.3	0.0075	22,26	0.0025
19,22	0.0300	16,16	0.0625	14,15	0.0400	23,23	0.0150
19,23	0.0075	16,17	0.0925	14,15.3	0.0025	23,24	0.0300
19,24	0.0025	16,18	0.0025	14,16	0.0050	23,25	0.0050
20,20	0.0175	17,17	0.0375	14.3,14.3	0.0025	24,24	0.0025
20,21	0.0650	17,18	0.0075	15,15	0.0075	24,25	0.0050
20,22	0.0250			15,16	0.0025
20,23	0.0125
20,24	0.0050
21,21	0.0850
21,22	0.1025
21,23	0.0125
21,24	0.0075
22,22	0.0225
22,23	0.0075
23,23	0.0025

附表1

表5

北方汉族81个常染色体STR基因座的群体遗传学参数"

基因座	DP	Ho	He	PIC	PE_Tri	PE_Duo	P值
PentaE	0.9845	0.9075	0.9166	0.9092	0.8108	0.7069	0.1488
D20S470*	0.9693	0.8800	0.8762	0.8620	0.7548	0.5938	0.4873
D7S1517^*	0.9684	0.8800	0.8753	0.8609	0.7548	0.5910	0.4979
D7S3048^*	0.9681	0.8950	0.8747	0.8602	0.7852	0.5888	0.6681
D2S1338	0.9660	0.8825	0.8677	0.8523	0.7598	0.5747	0.8549
D2S1772^#	0.9638	0.8450	0.8604	0.8455	0.6850	0.5661	0.1562
D6S1043	0.9638	0.9075	0.8698	0.8544	0.8108	0.5777	0.0202
FGA	0.9608	0.8575	0.8560	0.8389	0.7097	0.5508	0.1139
D10S2325^#	0.9608	0.8500	0.8514	0.8358	0.6949	0.5492	0.4513
D18S51	0.9600	0.8675	0.8566	0.8397	0.7296	0.5523	0.9327
D8S1132	0.9597	0.8750	0.8549	0.8365	0.7447	0.5405	0.9234
D8S1179	0.9574	0.8450	0.8515	0.8328	0.6850	0.5346	0.0331
D18S1364^*	0.9545	0.8525	0.8465	0.8265	0.6998	0.5232	0.4700
D11S2368^*	0.9541	0.8550	0.8476	0.8277	0.7047	0.5246	0.2475
D12S391	0.9524	0.8200	0.8372	0.8159	0.6367	0.5053	0.5033
D15S659	0.9521	0.8325	0.8416	0.8211	0.6607	0.5134	0.0375
D22GATA198B05^*	0.9517	0.8325	0.8339	0.8147	0.6607	0.5075	0.5822
D13S305^#	0.9506	0.8400	0.8363	0.8149	0.6753	0.5043	0.2808
D9S1118^#	0.9491	0.8100	0.8318	0.8083	0.6177	0.4885	0.7884
D1S1656	0.9478	0.8100	0.8236	0.8021	0.6177	0.4884	0.3853
D14S608^*	0.9447	0.8175	0.8242	0.7996	0.6319	0.4758	0.8855
D3S1744^*	0.9436	0.8025	0.8163	0.7936	0.6037	0.4706	0.1460
D19S433	0.9419	0.7975	0.8084	0.7833	0.5944	0.4562	0.7554
D5S1505^#	0.9417	0.8500	0.8226	0.7986	0.6949	0.4760	0.6386
D19S400^#	0.9416	0.7925	0.8109	0.7884	0.5852	0.4645	0.7867
D17S1290^*	0.9416	0.8275	0.8185	0.7941	0.6510	0.4714	0.3540
D21S11	0.9394	0.8175	0.8099	0.7854	0.6319	0.4604	0.6344
D21S1270^*	0.9390	0.7875	0.8147	0.7914	0.5761	0.4704	0.0004
PentaD	0.9369	0.8075	0.8109	0.7857	0.6130	0.4550	0.4933
D18S535^*	0.9325	0.8100	0.8052	0.7772	0.6177	0.4406	0.2018
D21S1442^#	0.9316	0.8000	0.8013	0.7740	0.5990	0.4405	0.7376
D16S539	0.9296	0.7925	0.8037	0.7731	0.5852	0.4293	0.3747
D6S477	0.9295	0.7950	0.7970	0.7663	0.5898	0.4224	0.8677
D3S2459^#	0.9281	0.8025	0.7956	0.7655	0.6037	0.4214	0.9232
D13S317	0.9277	0.7950	0.8030	0.7727	0.5898	0.4290	0.1085
D9S925^*	0.9275	0.7750	0.7956	0.7639	0.5535	0.4175	0.6850
D16S3391^#	0.9266	0.8025	0.7973	0.7674	0.6037	0.4244	0.1816
vWA	0.9257	0.8150	0.8015	0.7705	0.6272	0.4261	0.6481
D20S85^#	0.9255	0.8100	0.7899	0.7632	0.6177	0.4230	0.0097
D22S684^#	0.9241	0.7950	0.7900	0.7580	0.5898	0.4114	0.9957
D19S253	0.9222	0.7625	0.7828	0.7518	0.5314	0.4050	0.2000
D1S2142^#	0.9217	0.8000	0.7827	0.7508	0.5990	0.4016	0.8700
D3S3045	0.9194	0.7925	0.7839	0.7521	0.5852	0.4035	0.8430
D12S1064^#	0.9191	0.7725	0.7731	0.7414	0.5490	0.3955	0.874
D20S161^#	0.9183	0.7725	0.7733	0.7419	0.5490	0.3914	0.7669
D13S325^*	0.9181	0.7975	0.7869	0.7539	0.5944	0.4066	0.3532
D5S818	0.9170	0.7525	0.7778	0.7426	0.5141	0.3882	0.6507
D5S2500^*	0.9114	0.7950	0.7789	0.7465	0.5898	0.3995	0.3345
D7S820	0.9113	0.7600	0.7683	0.7325	0.5270	0.3779	0.3173
D2S441	0.9112	0.7625	0.7694	0.7337	0.5314	0.3791	0.8017
D3S1545^#	0.9072	0.7450	0.7633	0.7257	0.5013	0.3674	0.4730
D22S1045	0.9053	0.7650	0.7672	0.7261	0.5358	0.3617	0.9014
D10S1435	0.9052	0.7600	0.7639	0.7281	0.5270	0.3731	0.0553
D1S549^#	0.9037	0.7975	0.7734	0.7385	0.5944	0.3860	0.1260
D2S1776^*	0.9026	0.7200	0.7484	0.7083	0.4599	0.3495	0.4932
D11S4463^*	0.8988	0.7700	0.7587	0.7184	0.5446	0.3580	0.1860
D4S2408^*	0.8943	0.7400	0.7526	0.7081	0.4928	0.3399	0.3222
CSF1PO	0.8940	0.7225	0.7496	0.7085	0.4639	0.3461	0.3617
D17S974^*	0.8932	0.7400	0.7430	0.7030	0.4928	0.3385	0.6784
D10S1248	0.8895	0.7000	0.7308	0.6910	0.4283	0.3266	0.2661
D3S4529^*	0.8863	0.7500	0.7368	0.6938	0.5098	0.3256	0.5285
D20S482^*	0.8829	0.7125	0.7292	0.6855	0.4479	0.3220	0.7439
D3S1358	0.8788	0.7200	0.7265	0.6792	0.4599	0.3137	0.6601
D4S2366^*	0.8782	0.7625	0.7326	0.6897	0.5314	0.3293	0.3245
D8S1115^#	0.8778	0.6950	0.7087	0.6698	0.4206	0.3075	0.2069
D9S1122^*	0.8750	0.7475	0.7316	0.6861	0.5055	0.3226	0.1190
D17S1301^*	0.8672	0.7050	0.6982	0.6561	0.4360	0.2923	0.4876
D14S1434^*	0.8652	0.7100	0.7013	0.6560	0.4439	0.2917	0.8846
D3S3053^#	0.8621	0.6875	0.7012	0.6473	0.4092	0.2793	0.3570
D6S474^*	0.8562	0.7175	0.7074	0.6556	0.4558	0.2899	0.0211
D6S1017^*	0.8536	0.7200	0.6980	0.6459	0.4599	0.2780	0.7957
D5S2800^*	0.8481	0.7175	0.6958	0.6426	0.4558	0.2731	0.1637
TH01	0.8362	0.6450	0.6637	0.6116	0.3484	0.2532	0.1719
D20S1082^*	0.8315	0.7125	0.6769	0.6175	0.4479	0.2579	0.2566
D1S1677^*	0.8235	0.6225	0.6572	0.5995	0.3188	0.2427	0.2610
D1GATA113^*	0.8109	0.6350	0.6410	0.5754	0.3350	0.2178	0.3605
TPOX	0.8076	0.6250	0.6331	0.5717	0.3220	0.2171	0.7349
D4S2364^#	0.7963	0.7025	0.6587	0.5892	0.4321	0.2260	0.1735
D2S1360^#	0.7961	0.6250	0.5905	0.5587	0.3220	0.2055	0.2010
D1S1627^*	0.7793	0.6500	0.6062	0.5450	0.3552	0.1982	0.0425
LPL^#	0.6332	0.4375	0.4314	0.3938	0.1384	0.0955	0.0304

表5

表6

表7

表8

参考文献 34

[1]	Hammond HA, Jin L, Zhong Y, Caskey CT, Chakraborty R. Evaluation of 13 short tandem repeat loci for use in personal identification applications. Am J Hum Genet, 1994, 55(1): 175-189. pmid: 7912887
[2]	Edwards A, Hammond HA, Jin L, Caskey CT, Chakraborty R. Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups. Genomics, 1992, 12(2): 241-253. pmid: 1740333
[3]	Zhang SH, Niu Y, Bian YN, Dong RX, Liu XL, Bao Y, Jin C, Zheng HC, Li CT. Sequence investigation of 34 forensic autosomal STRs with massively parallel sequencing. Sci Rep, 2018, 8(1): 6810. pmid: 29717145
[4]	Gouy A, Zieger M. STRAF 2: new features and improvements of the STR population data analysis software. Forensic Sci Int Genet, 2025, 76: 103207. pmid: 39662282
[5]	Excoffier L, Lischer HEL. Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour, 2010, 10(3): 564-567. pmid: 21565059
[6]	Lincoln PJ. DNA recommendations--further report of the DNA commission of the ISFH regarding the use of short tandem repeat systems. Forensic Sci Int, 1997, 87(3): 181-184. pmid: 9248037
[7]	Wang HD, Kang B, Su N, He M, Zhang B, Guo YX, Zhu BF, Liao SX, Zeng ZS. Evaluation of the genetic parameters and mutation analysis of 22 STR loci in the central Chinese Han population. Int J Legal Med, 2017, 131(1): 103-105. pmid: 27225389
[8]	Filoglu G, Bulbul O, Rayimoglu G, Yediay FE, Zorlu T, Ongoren S, Altuncul H. Evaluation of reliability on STR typing at leukemic patients used for forensic purposes. Mol Biol Rep, 2014, 41(6): 3961-3972. pmid: 24562624
[9]	黄玥蕾, 谢波, 陈海英, 唐金晶. 江西赣州地区汉族人群19个STR基因座遗传多态性. 中国法医学杂志, 2015, 30(3): 293-294.
[10]	Schmid D, Anslinger K, Rolf B. Allele frequencies of the ACTBP2 (=SE33), D18S51, D8S1132, D12S391, D2S1360, D3S1744, D5S2500, D7S1517, D10S2325 and D21S2055 loci in a German population sample. Forensic Sci Int, 2005, 151(2-3): 303-305. pmid: 15939167
[11]	Ozeki M, Tamaki K. Allele frequencies of 37 short tandem repeat loci in a Japanese population. Leg Med (Tokyo), 2013, 15(6): 342-346. pmid: 24112991
[12]	Červenák Z, Mikula M, Červenák F, Choma A, Masnicová S. Population and forensic analysis of 9 non-CODIS markers in Slovak population. Leg Med (Tokyo), 2021, 53: 101953. pmid: 34411796
[13]	张勇, 丁梅, 王保捷, 庞灏, 刘清利, 孙志刚. 中国汉族、维吾尔族、哈萨克族D3S1744、D18S849基因座的遗传多态性. 中国法医学杂志, 2004, 19(1): 46-47.
[14]	Chung U, Shin KJ, Park MJ, Kim NY, Yang WI, Cho SH, Lee HY. Population data of nine miniSTR loci in Koreans. Forensic Sci Int, 2007, 168(2-3): e51-e53. pmid: 17346912
[15]	Liu QL, Huang KK, Wu YD, Zhao H, Li CT, Lu DJ. Genetic polymorphism of 13 non-CODIS STR loci in three national populations from China. Electrophoresis, 2014, 35(23): 3395-3401. pmid: 25100665
[16]	Wiegand P, Klintschar M. Population genetic data, comparison of the repeat structure and mutation events of two short STRs. Int J Legal Med, 2002, 116(5): 258-261. pmid: 12376833
[17]	Kitayama T, Kiesler KM, Fukagawa T, Watahiki H, Mita Y, Fujii K, Sekiguchi K, Vallone PM, Mizuno N. Massively parallel sequencing data of 31 autosomal STR loci obtained using the Precision ID GlobalFiler NGS STR Panel v2 for 82 Japanese population samples. Leg Med (Tokyo), 2022, 58: 102082. pmid: 35584562
[18]	Iyavoo S, Afolabi O, Boggi B, Bernotaite A, Haizel T. Population genetics data for 22 autosomal STR loci in European, South Asian and African populations using SureID^® 23comp Human DNA Identification Kit. Forensic Sci Int, 2019, 301: 174-181. pmid: 31167154
[19]	Abrahams Z, D'Amato ME, Davison S, Benjeddou M. Allele frequencies of six non-CODIS miniSTR loci (D1S1627, D3S4529, D5S2500, D6S1017, D8S1115 and D9S2157) in three South African populations. Forensic Sci Int Genet, 2011, 5(4): 354-355. pmid: 20457088
[20]	Jin HJ, Kim KC, Yoon CE, Kim W. Forensic and population genetic analyses of eighteen non-CODIS miniSTR loci in the Korean population. J Forensic Leg Med, 2013, 20(8): 1093-1097. pmid: 24237828
[21]	Shi YF, Li XZ, Ju D, Li Y, Zhang XL, Zhang Y. Genetic polymorphisms of short tandem repeat loci D13S305, D13S631 and D13S 634 in the Han population of Tianjin, China. Exp Ther Med, 2015, 10(2): 773-777. pmid: 26622392
[22]	Wu J, Li YB, Hou YP, Zhang J, Yan J, Liao M, Lin JD, He Y. Polymorphisms of seven short tandem repeat loci: D1S2142, D1S3733, D2S1774, D3S2459, D21S1409, D21S1437 and D21S2055 of Chinese Han population in Chengdu. Chin J Med Genet, 2006, 23(2): 230-233.
	吴谨, 李英碧, 侯一平, 张霁, 颜静, 廖淼, 林金东, 何艳. 成都汉族群体七个短串联重复序列基因座的遗传多态性和法医学应用研究. 中华医学遗传学杂志, 2006, 23(2): 230-233.
[23]	He P, Nata M, Kanetake J, Ji G, Yan W, Li X, Sagisaka K. Polymorphism of short tandem repeat (STR) loci PLA2, D3S2459, D8S 315 (kw38), CYP19, D3S1359, FGA, and D8S1132 in the Japanese and Chinese populations. Tohoku J Exp Med, 1997, 183(4): 251-262. pmid: 9549825
[24]	Ohtaki H, Yamamoto T, Yoshimoto T, Uchihi R, Ooshima C, Katsumata Y, Tokunaga K. A powerful, novel, multiplex typing system for six short tandem repeat loci and the allele frequency distributions in two Japanese regional populations. Electrophoresis, 2002, 23(19): 3332-3340. pmid: 12373760
[25]	龙兵, 张德明, 王晶, 陈国第. 中国汉族、回族和泰国人群D12S1064、GATA158G03遗传多态性. 中国法医学杂志, 2009, 24(5): 328-329.
[26]	Wang W, Okazaki K, Kishida T, Fukuda M, Tamaki Y. Subtyping of D20S85 STR alleles by single-strand conformation polymorphism (SSCP) analysis. Forensic Sci Int, 1997, 86(3): 187-192. pmid: 9180028
[27]	Lu HL, Zhang W. Study on genetic polymorphisms of STR locus D20S 85 in five Chinese populations and forensic application. Chin J Forensic Med, 2002, 17(5): 259-262.
	陆惠玲, 张炜. 中国5个群体D20S85基因座的遗传多态性. 中国法医学杂志, 2002, 17(5): 259-262.
[28]	Miao L, Kang KL, Zhang C, Liu S, Jiao RL, Yuan L, Wang L. Sequence features of forensic core short tandem repeat loci. Hereditas(Beijing), 2025, 47(11): 1214-1230.
	缪磊, 康克莱, 张驰, 刘爽, 焦瑞莲, 袁丽, 王乐. 法庭科学核心STR基因座的序列特征. 遗传, 2025, 47(11): 1214-1230.
[29]	Gill P, Urquhart A, Millican E, Oldroyd N, Watson S, Sparkes R, Kimpton CP. A new method of STR interpretation using inferential logic—development of a criminal intelligence database. Int J Legal Med, 1996, 109(1): 14-22. pmid: 8876317
[30]	Zhang XF, Liu LL, Xie RF, Wang GY, Shi Y, Gu T, Hu LP, Nie SJ. Population data and mutation rates of 20 autosomal STR loci in a Chinese Han population from Yunnan Province, Southwest China. Int J Legal Med, 2018, 132(4): 1083-1085. pmid: 28887705
[31]	黄健, 吴华, 汤美云, 蔡金洪. vWA和D12S391基因座在亲缘关系个体中的连锁分析. 中国法医学杂志, 2015, 30(2): 180-181.
[32]	Liu QL, Chen YF, Huang XL, Liu KY, Zhao H, Lu DJ. Population data and mutation rates of 19 STR loci in seven provinces from China based on Goldeneye™ DNA ID System 20A. Int J Legal Med, 2017, 131(3): 653-656. pmid: 27623972
[33]	Zhang BL, Li Z, Li K, Chen P, Chen F. Forensic parameters and mutation analysis of 23 short tandem repeat (PowerPlex® Fusion System) loci in Fujian Han Chinese population. Leg Med (Tokyo), 2019, 37: 33-36. pmid: 30612022
[34]	Su LJ, Wang YX, Shan X, Qiu Y, Xi SH, Hu RP. Observation and analysis of gene mutations in 306 parentage testing cases. Genomics and Applied Biology, 2019, 38(8): 3511-3514.
	苏丽娟, 王忆霄, 单鑫, 邱阳, 席世涵, 扈瑞平. 306例亲子鉴定案件基因突变的观察与分析. 基因组学与应用生物学, 2019, 38(8): 3511-3514.

编辑推荐

Metrics

www.chinagene.cn
备案号：京ICP备09063187号-4
总访问:,今日访问:,当前在线:

基因座信息	GB/T 41009-2021中收录	GB/T 44393-2024中收录	本研究确认结果
物理坐标	Chr18:40568863~40568929	Chr18:40568863~40568929	Chr18:40568879~40568930
重复区序列	AGATAGACAGATAGATGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGAT	AGATAGACAGATAGATGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGAT	GATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATA
重复结构	[AGAT]_aAGAC[AGAT]_bGAT[AGAT]_c	[GATA]_a	[GATA]_a

试剂盒	CDP	CPE_Tri	CPE_Duo	平均DP值
GSTAR^TM25 (试剂1)	1-7.40×10^-28	1-3.96×10^-10	1-9.93×10^-7	0.9237
GSTAR^TM31FS(试剂2)	1-6.54×10^-37	1-8.71×10^-14	1-1.15×10^-5	0.9334
GSTAR^TM29HS(试剂3)	1-7.20×10^-27	1-8.01×10^-9	1-8.01×10^-9	0.8681
试剂1、2联用	1-4.84×10^-64	1-3.45×10^-23	1-8.94×10^-15	0.9290
试剂1、3联用	1-5.33×10^-54	1-3.17×10^-18	1-1.14×10^-11	0.8959
试剂2、3联用(不统计D5S2800基因座)	1-3.10×10^-62	1-1.28×10^-22	1-1.42×10^-13	0.9033
试剂1、2、3联用(不统计D5S2800基因座)	1-2.29×10^-89	1-5.07×10^-31	1-1.40×10^-19	0.9092

基因座	子女分型	母亲分型	父亲分型	突变步数	突变来源	突变率	置信区间
D11S2368	18，21	18	17，20	+1	父亲	0.004	[5.0×10^-4,1.44×10^-2]
D11S2368	19，21	19，21	18	+1	父亲	0.004	[5.0×10^-4,1.44×10^-2]
D13S325	21，22	20，22	19，20	+1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D7S1517	24，28	23，24	17，27	+1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D11S4463	12，16	12，14	14，17	-1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D20S482	9，15	9，13	12，14	+1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D14S1434	12，13	13	13	-1	不明	0.002	[1.0×10^-4,1.15×10^-2]
D20S85	15，18	13，15	10，17	+1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D6S1043	14，19	11，14	12，18	+1	父亲	0.002	[1.0×10^-4,1.15×10^-2]
D18S51	13，14	13，18	13，15	-1	父亲	0.004	[5.0×10^-4,1.44×10^-2]
D18S51	13，14	13，18	13，15	-1	父亲	0.004	[5.0×10^-4,1.44×10^-2]
D5S818	11，14	11，13	12，13	+1	父亲	0.004	[5.0×10^-4,1.44×10^-2]
D5S818	12，14	12，13	11，12	+1	母亲	0.004	[5.0×10^-4,1.44×10^-2]

基因座	对比人群	P值
D2S1360	日本东京大和族人群^[11]	<0.001
D3S1744	日本东京大和族人群^[11]	0.003
D3S3053	内蒙古蒙古族人群^[15]	0.783
	伊犁维吾尔族人群^[15]	0.010
	塔城哈萨克族人群^[15]	0.012
D3S1545	德国高加索诸民族人群^[16]	<0.001
D5S2800	欧洲欧裔多民族人群^[18]	<0.001
	南亚地区多民族人群^[18]	<0.001
	非洲地区多民族人群^[18]	<0.001
D8S1115	韩国首尔朝鲜族人群^[20]	<0.001
D13S305	天津汉族人群^[21]	<0.001

中国北方汉族人群81个常染色体STR基因座多态性研究及突变调查

Genetic polymorphism and mutation analysis of 81 autosomal STR loci in the Northern Han Chinese population

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 10

参考文献 34

相关文章 15

编辑推荐

Metrics

基因座	GB/T 41009-2021中重复结构	GB/T 44393-2024中重复结构	GB/T 44322-2024中9948的重复区序列	本研究中9948分型
D3S4529	[GATA]_aAATA[GATA]_b	[AGAT]_aAAAT[AGAT]_b	[AGAT]₄AAAT[AGAT]₇	12
D11S4463	[TATC]_a	[TATC]_aTATGTATC	[TATC]₁₀TATGTATC	12
D11S4463	[TATC]_a	[TATC]_aTATGTATC	TGTC[TATC]₁₁TATGTATC	14
D14S608	[GATA]_aN₁₂[GATA]_bGACA[GATA]_c	[GATA]_a	[GATA]₁₂	12
D17S974	[ATAG]_aATG[ATAG]_b	[ATAG]_a	[ATAG]₁₀	10
D17S974	[ATAG]_aATG[ATAG]_b	[ATAG]_a	[ATAG]₁₁	11
D17S1290	[AGAT]_aN₂₈[ATAG]_b	−	−	14
D17S1290	[AGAT]_aN₂₈[ATAG]_b	−	−	15
D21S1270	[ATAG]_aATG[ATAG]_bATG[ATAG]_c	[ATAG]_aATG[ATAG]_bATG[ATAG]_c	[ATAG]₃ATG[ATAG]ATG[ATAG] ATG[ATAG]₈	13.3
D21S1270	[ATAG]_aATG[ATAG]_bATG[ATAG]_c	[ATAG]_aATG[ATAG]_bATG[ATAG]_c	[ATAG]₃ATG[ATAG]ATG[ATAG]₁₁	15

[1]	缪磊, 张驰, 康克莱, 白雪, 郭柯利, 袁丽, 王乐. 41个法庭科学Y-STR基因座的序列多态性特征分析与应用[J]. 遗传, 2026, 48(4): 355-376.
[2]	缪磊, 康克莱, 张驰, 刘爽, 焦瑞莲, 袁丽, 王乐. 法庭科学核心STR基因座的序列特征[J]. 遗传, 2025, 47(11): 1214-1230.
[3]	朱信, 金鑫, 刘俊, 杨澜, 邹丽馨, 李彩霞, 黄江, 江丽. 基于Y-SNP和Y-STR揭示汉族人群父系遗传关系[J]. 遗传, 2024, 46(2): 149-167.
[4]	李鑫, 范虹, 赵兴春, 范晓诺, 姚若侠. 基于全局最小残差法快速分析混合STR图谱[J]. 遗传, 2023, 45(10): 933-944.
[5]	孔永强, 刘金凯, 顾佳琪, 徐景怡, 郑雨诺, 魏以梁, 伍少远. 南-北方汉族人、韩国人和日本人遗传划分机器学习模型优化方案[J]. 遗传, 2022, 44(11): 1028-1043.
[6]	郭晓媛, 孙昌春, 薛思瑶, 赵慧, 江丽, 李彩霞. 49AISNP：东亚北方三个族群遗传来源推断[J]. 遗传, 2021, 43(9): 880-889.
[7]	李茜, 王浩宇, 曹悦岩, 朱强, 舒潘寅, 侯婷芸, 王雨婷, 张霁. 微单倍型遗传标记的法医基因组学研究[J]. 遗传, 2021, 43(10): 962-971.
[8]	刘志勇, 乌日嘎, 李燃, 王蔷薇, 孙宏钰. 法医遗传学研究和鉴定中的伦理问题[J]. 遗传, 2021, 43(10): 994-1002.
[9]	刘杨, 孙昌春, 马咪, 王玲, 赵雯婷, 马泉, 季安全, 刘京, 李彩霞. 74-plex SNPs复合检测体系在中国人群中的族群推断研究[J]. 遗传, 2020, 42(3): 296-308.
[10]	江丽,孙启凡,马泉,赵雯婷,刘京,赵蕾,季安全,李彩霞. 27-plex SNP种族推断方法的优化及验证[J]. 遗传, 2017, 39(2): 166-173.
[11]	阮修艳, 王伟妮, 杨雅冉, 谢兵兵, 陈婧, 刘雅诚, 严江伟. 北京汉族群体39个短串联重复序列基因座多态性及其遗传关系[J]. 遗传, 2015, 37(7): 683-691.
[12]	畅荣妮袁广之谭建强赖青鸟马军杨益金舒伟侯伟袁志刚. 广西一脊髓小脑共济失调3型家系SCA3/MJD基因突变和多态性的分析[J]. 遗传, 2013, 35(11): 1300-1306.
[13]	李佳薏，姚永芳，周亮，徐怀亮. 藏酋猴Mhc-DPB1基因exon 2的多态性[J]. 遗传, 2012, 34(11): 1417-1426.
[14]	石美森，百茹峰，傅博. 山西汉族17个Y-STR基因座遗传多态性及遗传关系[J]. 遗传, 2011, 33(3): 228-238.
[15]	陈仁金，杨章平，毛永江，陈莹，常玲玲，冀德君，吴海涛，李云龙，李锐. 中国荷斯坦牛IL8基因遗传多态性与泌乳性状以及体细胞评分的关联[J]. 遗传, 2010, 32(12): 1256-1262.