遗传 ›› 2023, Vol. 45 ›› Issue (9): 754-764.doi: 10.16288/j.yczz.23-165

• 综述 • 上一篇    下一篇

植物开花调控中蛋白质相分离机制在从头驯化中的应用价值

田璐妍1,2(), 黄小珍1()   

  1. 1.中国科学院遗传与发育生物学研究所,植物基因组学国家重点实验室,北京 100101
    2.中国科学院大学,北京 100049
  • 收稿日期:2023-06-12 修回日期:2023-07-15 出版日期:2023-09-20 发布日期:2023-08-01
  • 通讯作者: 黄小珍 E-mail:lytian@genetics.ac.cn;xzhuang@genetics.ac.cn
  • 作者简介:田璐妍,硕士研究生,专业方向:遗传学。E-mail: lytian@genetics.ac.cn
  • 基金资助:
    国家重点研发计划项目(2018YFA0900603);三亚崖州湾科技城管理局2021年度科技计划项目(SKJC-2021-02-002);中国科学院青年创新促进会项目(2022094)

Application value of protein phase separation mechanism of flowering regulation in de novo domestication

Luyan Tian1,2(), Xiaozhen Huang1()   

  1. 1. State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China
    2. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2023-06-12 Revised:2023-07-15 Online:2023-09-20 Published:2023-08-01
  • Contact: Xiaozhen Huang E-mail:lytian@genetics.ac.cn;xzhuang@genetics.ac.cn
  • Supported by:
    Supported by National Key R&D Program of China(2018YFA0900603);2021 Research Program of Sanya Yazhou Bay Science and Technology City(SKJC-2021-02-002);Youth Innovation Promotion Association of the Chinese Academy of Sciences(2022094)

摘要:

全球气候变化和人口快速增长严重威胁世界粮食安全,现有作物难以满足人类未来的粮食需求,亟需高产优质且环境适应性强的作物品种。利用野生种质资源进行快速从头驯化,获得可应用于育种的新种质是应对粮食安全问题的新策略。开花时间性状是决定作物种植区域和最终产量的重要因素,在作物驯化中常常受到选择。目前在从头驯化中,通常直接利用控制作物开花的主效基因来改造开花性状,基因数量非常有限且功能较为单一。植物成花转变受到环境和内源性信号的复杂调控,本文提出利用调控开花基因表达的重要蛋白质的可逆行为变化——蛋白质相分离定向改造蛋白功能,从而精准控制开花相关基因的表达,可能为从头驯化中开花性状的分子设计提供新的选择。

关键词: 成花转变, 开花时间, 蛋白质相分离, 从头驯化

Abstract:

Global climate change and population growth pose a serious threat to world food security. The current crops varieties will be insufficient to meet food needs in the future, and there is an urgent need for high yielding and quality crops varieties with strong environmental adaptability. The rapid de novo domestication of wild species to create new germplasm that can be applied to crop breeding is a new strategy for ensuring food security. The flowering time is an important factor in determining the crop planting area and yield, and is a trait that is often selected in crop domestication. At present, the modification of flowering traits by de novo domestication is usually achieved by direct editing of the major genes that control flowering in crop, which are very limited in number and relatively homogeneous in function. Floral transition is regulated by the complex network of environmental and endogenous signals. Here, we propose a new strategy that using genome editing to precisely modify protein function by changing protein phase separation capacity of important proteins that regulate expression of flowering genes, which may provide new options for the design of flowering traits in de novo domestication.

Key words: floral transition, flowering time, protein phase separation, de novo domestication