遗传 ›› 2013, Vol. 35 ›› Issue (12): 1360-1367.doi: 10.3724/SP.J.1005.2013.01360

• 综述 • 上一篇    下一篇

组学技术评价转基因农作物的非预期效应

赵艳, 李燕燕   

  1. 浙江工商大学食品与生物工程学院, 杭州310018
  • 收稿日期:2013-06-11 修回日期:2013-09-20 出版日期:2013-12-20 发布日期:2013-11-20
  • 通讯作者: 赵艳, 博士, 教授, 研究方向:植物生化与分子生物学。Tel: 0571-88071024-7579 E-mail:yanzhao9918@163.com
  • 作者简介:赵艳, 博士, 教授, 研究方向:植物生化与分子生物学。Tel: 0571-88071024-7579 E-mail: yanzhao9918@163.com
  • 基金资助:

    国家自然科学基金项目(编号:30871511)和农业部转基因新品种培育重大专项项目(编号:2011ZX08010-003)资助

Unintended effects assessment of genetically modified crops using omics techniques

ZHAO Yan, LI Yan-Yan   

  1. College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China
  • Received:2013-06-11 Revised:2013-09-20 Online:2013-12-20 Published:2013-11-20

摘要:

安全性评价是转基因农作物商品化应用的必要环节。组学技术能在转录物、蛋白质、代谢物水平上对转基因农作物进行无偏倚的安全性评价。文章综述了近10年来应用转录组学、蛋白质组学和代谢物组学技术评价转基因农作物非预期效应的研究进展, 结果表明在转基因农作物非预期变异中, 环境因素(种植地点和季节)和基因型差异比转基因本身的影响更大。

关键词: 转基因农作物, 非预期效应, 转录组学, 蛋白质组学, 代谢组学

Abstract:

Safety assessment is the essential process for commercial application of genetically modified (GM) crops. Omics techniques can be used to evaluate the safety of GM crops unbiasedly at different biological levels, such as transcripts, proteins and metabolites. In the present review, the researches on unintended effects assessment of GM crops using transcriptomic, proteomic and metablomic techniques in recent ten years have been summarized. The facts show that the environmental factors (growing area and season) and genotype difference play greater roles than gene insertion does for most unintended variations in GM crops.

Key words: genetically modified crops, unintended effects, transcriptomics, proteomics, metabolomics