蛋白质修饰组学在肉品质研究中的应用

doi:10.16288/j.yczz.14-417

遗传 ›› 2015, Vol. 37 ›› Issue (4): 327-335.doi: 10.16288/j.yczz.14-417

蛋白质修饰组学在肉品质研究中的应用

蒲强,罗嘉,沈林園,李学伟,张顺华,朱砺

四川农业大学动物科技学院,成都 611130

收稿日期:2014-11-30 出版日期:2015-04-20 发布日期:2015-02-13
通讯作者: 张顺华,博士,硕士生导师,研究方向：猪的遗传育种。E-mail：363445986@qq.com;朱砺,教授,博士生导师,研究方向：猪的遗传育种。E-mail：zhuli7508@163.com E-mail:461662559@qq.com;1028400278@qq.com
作者简介:蒲强,硕士研究生,专业方向：猪的遗传育种。E-mail: 461662559@qq.com;罗嘉,硕士研究生,专业方向：猪的遗传育种。E-mail:1028400278@qq.com
基金资助:
四川省科技支撑计划项目(编号：2013NZ0041),国家科技支撑计划项目(编号：2013BAD20B07),和教育部长江学者和创新团队发展计划(编号：IRT13083)资助

Application of modification-specific proteomics in the meat-quality study

Qiang Pu,Jia Luo,Linyuan Shen,Xuewei Li,Shunhua Zhang,Li Zhu

College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China

Received:2014-11-30 Online:2015-04-20 Published:2015-02-13

摘要/Abstract

摘要： 蛋白质翻译后修饰(Post-translational modifications, PTMs)在生命体中具有十分重要的作用。生命有机体中常见的PTMs有磷酸化、酰化、糖基化、泛素化、乙酰化、氧化和甲基化等。文章主要介绍了蛋白质组学在肉制品科学方面的应用、PTMs的主要内容以及分析蛋白修饰特性常见技术的发展,总结了PTMs对肌肉生理特性的影响和蛋白质组学方法在肉质蛋白质修饰研究中的重要性及前景,讨论了利用蛋白质修饰组学技术研究肌肉熟化过程中品质特性变化的特点。

关键词: 蛋白质组学, 肌肉, 翻译后修饰, 肉质

Abstract: Post-translational modifications (PTMs) play an important role in life science. The most widely studied protein modifications in biological science include protein phosphorylation, acylation, glycosylation, ubiquitination, acetylation, oxidation, methylation and so on. This review outlines current achievements in the study of protein modifications in muscle food using proteomic approaches. First we describe the general knowledge of protein modifications and then the development of proteomic approaches for the characterization of such modifications. Second, we describe the effects of protein modifications on muscle foods and devote our main attention to the application of proteomic approaches for the analysis of these modifications. We conclude that proteomics analysis is powerful for the study of protein modifications and analysis of meat quality characteristics in the process of food production.

Key words: proteomics, muscle, post-translational modifications (PTMs), meat quality

蒲强,罗嘉,沈林園,李学伟,张顺华,朱砺. 蛋白质修饰组学在肉品质研究中的应用[J]. 遗传, 2015, 37(4): 327-335.

Qiang Pu,Jia Luo,Linyuan Shen,Xuewei Li,Shunhua Zhang,Li Zhu. Application of modification-specific proteomics in the meat-quality study[J]. HEREDITAS(Beijing), 2015, 37(4): 327-335.

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蛋白质修饰组学在肉品质研究中的应用

Application of modification-specific proteomics in the meat-quality study

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