海南省鼻咽癌三个高发家系报告

遗传 ›› 1998, Vol. 20 ›› Issue (6): 19-21.

海南省鼻咽癌三个高发家系报告

符生苗; 王海枫; 肖翰; 林少民; 黄奕江; 雷颖 FU Sheng-maio;WANG Hai-feng;XIAO Han;LIN Xao-ming;HUANG Yi-jing;LEI Ying

海南省人民医院遗传室, 海口 570311 Genet Laboratory,The Peoples Hospital of Hainan Province,Haikou 570311

收稿日期:1900-01-01 出版日期:1998-12-10 发布日期:1998-12-10

Report Three Families with High Incidence of Nasopharyngeal Carcinoma in Hainan Province

Received:1900-01-01 Online:1998-12-10 Published:1998-12-10

摘要/Abstract

摘要： 本文调查了鼻咽癌聚集的10个家系。在3个高发家族中,家系1两代11人中有4
人患鼻咽癌;家系2同代6人中有3人患鼻咽癌;家系3同胞5人中有3人患鼻咽癌。我们从肿瘤流行病学、病理类型及其血缘关系作了分析,认为鼻咽癌具有垂直和水平的家族发生
倾向,支持鼻咽癌有遗传倾向的看法。
Abstract:We studied the genealogy with nasopharyngeal carcinoma(NPC)and found 25 patients (18 males,7 females)with NPC in 10 families,aged from 13 to 60.The bron of the same parents were 12 patients,accounting for 48% among these patients.Both male and female patients were found in five families;the patients in four families were all male;there were all female patients in the only one family;At the sametime,21 patients with NPC were the first kinsfolk in 8 families,accounting for 84%.Besides,we looked into 3 families with high incidence;there were 4 out of 11 family members suffering from NPC in the first genealogy in 2 generations;3 of 6 brons of the same parents were ill with NPC in the third genealogy.Based on the studies of cancer epidemiology,pathology and genealogy,our results suggested that the family incidence of NPC had vertical and horizontal thndency,and that genetic factors played a decisive role in NPC incidence.

关键词: 鼻咽癌, 家系分析, Nasopharyngeal carcinoma, Genealogy analysis, 遗传
Key words, 端粒重复顺序, 遗传定位, RM-PCR), 水稻(Oryza sativa L.), 端粒重复相关序列(TASs)

Key words: Telomeric repeat associated sequences, RM-PCR, Genetic mapping, Rice (Oryza sativa L.), Telomeric repeat

符生苗，王海枫，肖翰，林少民，黄奕江，雷颖. 海南省鼻咽癌三个高发家系报告[J]. 遗传, 1998, 20(6): 19-21.

FU Sheng-maio, WANG Hai-feng, XIAO Han, LIN Xao-ming, HUANG Yi-jing, LEI Ying. Report Three Families with High Incidence of Nasopharyngeal Carcinoma in Hainan Province [J]. HEREDITAS, 1998, 20(6): 19-21.

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