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前噬菌体的研究进展

陈学梅,魏云林,季秀玲   

  1. 昆明理工大学
  • 收稿日期:2020-11-27 修回日期:2021-01-12 出版日期:2021-01-14 发布日期:2021-01-14
  • 通讯作者: 季秀玲
  • 基金资助:
    国家自然科学基金项目

Research Progress of Prophages

mei xuechen1, ling xiuji1   

  • Received:2020-11-27 Revised:2021-01-12 Online:2021-01-14 Published:2021-01-14
  • Contact: ling xiuji

摘要: 噬菌体一直被认为是细菌的天敌。然而随着基因组学和分子生物学等技术的快速发展,发现宿主噬菌体与宿主之间存在微妙而复杂的关系。噬菌体能够整合到宿主基因组上,参与调节宿主的毒力及生物膜形成等。对前噬菌体的研究,有利于提高对噬菌体的认知,为改造宿主和噬菌体提供基础理论参考。本文对前噬菌体的分布、分类及功能进行了简要的概述。

关键词: 前噬菌体, 生物膜, 毒力, 溶原性

Abstract: Bacteriophages have always been regarded as the natural enemies of bacteria.With the rapidly development of genomics and molecular biology, it is found that there is a subtle and complex relationship between bacteriophages and host. Bacteriophages can be integrated into the host genome and participate in the regulation of host virulence and biofilm formation. The study of prophages is helpful to improve the cognition of bacteriophage and provide basic theoretical reference for the transformation of host and bacteriophage. In this paper, the distribution, classification and function of prophages were briefly summarized.

Key words: Prophage, Biofilm, Virulence factors, Lysogeny