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HEREDITAS ›› 2010, Vol. 32 ›› Issue (2): 135-140.doi: 10.3724/SP.J.1005.2010.00135

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Progresses on autosomal recessive nonsyndromic mental retardation related genes

SHI Zhang-Yan, ZHANG Fu-Chang, GAO Xiao-Cai   

  1. College of Life Science, Institute of Population and Health, Northwest University, Xi'an 710069, China
  • Received:2009-06-09 Revised:2009-09-06 Online:2010-02-20 Published:2010-01-15
  • Contact: fuchang zhang E-mail:zhfch@nwu.edu.cn

Abstract:

Some autosomal genes are associated with development and function of nervous system. Mutations of these genes can lead to nonsyndromic mental retardation. This paper reviews recent progresses on autosomal recessive nonsyndromic mental retardation related genes, including localization, expression, biological function and pathogenesis after mutations. The prospect in this field is also discussed.

Key words: nonsyndromic mental retardation, gene, autosomal