遗传 ›› 2012, Vol. 34 ›› Issue (4): 389-400.doi: 10.3724/SP.J.1005.2012.00389
赵翔, 韩宝达, 李立新
收稿日期:2011-10-18
修回日期:2011-11-24
出版日期:2012-04-20
发布日期:2012-04-25
通讯作者:
李立新
E-mail:lixinli1@gmail.com
基金资助:国家自然科学基金项目(编号：30840002, 30970223), 黑龙江省留学归国人员科学基金项目(编号：LC08C03), 中央高校基本科研业务费专项资金(编号：DL09DA02) , 东北林业大学引进人才科研启动金(编号：015-602042), 中国博士后科学基金特别资助(编号： 200902365)和黑龙江省留学人员科技活动项目择优资助(编号：2009-HLJLixinLi)
ZHAO Xiang, HAN Bao-Da, LI Li-Xin
Received:2011-10-18
Revised:2011-11-24
Online:2012-04-20
Published:2012-04-25
摘要： 大多数细胞内都包含靶向不同细胞器的各种运输囊泡, 其运输机制在进化上是高度保守的。Sec1/Munc- 18(SM)蛋白在膜泡运输中起着重要的调控作用,它能够与SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor)蛋白结合, 共同在细胞内各个膜融合发生部位发挥重要作用。SM蛋白和SNARE复合体中的Syntaxin蛋白结合, 调节SNARE复合体的装配, 并与SNARE协同作用促进整个膜融合过程。文章对SM蛋白在结构和功能分析方面的最新研究进展进行了概述。
赵翔，韩宝达，李立新. SM蛋白在膜泡运输中的功能[J]. 遗传, 2012, 34(4): 389-400.
ZHAO Xiang, HAN Bao-Da, LI Li-Xin. Function of SM protein in vesicle transport[J]. HEREDITAS, 2012, 34(4): 389-400.
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| [1] | 鲍永美，刘永惠，许冬清，黄骥，王州飞，王建飞，张红生. 水稻Qb-SNARE蛋白OsNPSN11多克隆抗体制备、鉴定与应用[J]. 遗传, 2010, 32(9): 961-965. |
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